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Theses/Dissertations from 2026

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Structural Insights into Host-Pathogen Interactions of Coronaviruses and Alphaviruses, Lucas Adams

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Role of Mesencephalic Reticular Formation Perineuronal Nets in Nociception, Migraine and Alcohol Withdrawal-induced Hyperalgesia, Jhoan Aguilar

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Inside 'n Out: ETV2 Specification of Hemangiogenic Lineages from FLK1+ Mesoderm, Dereck Antonio Shakeel Alleyne

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Valuation in Time: Mesolimbic Dopamine tracks Decision Strategy, Commitment and Persistence, Apoorva Arora

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Function, Regulation and Plasticity of Reactive Microglial States in Brain Development and Disease, Kia Marie Barclay

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Genetic Mechanisms of Urinary Tract Infection Pathogenesis by Escherichia coli, Jesus Bazan Villicana

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More than one way to keep an ILC in Line: Circadian and Epigenetic regulation of group 3 ILCs homeostasis, Bishan Bhattarai

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Impacts of Anthropogenic Landscape Change on Plant-Associated Microbes, Mahal Bugay

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Unraveling the Role of the C-Terminal Intrinsically Disordered Linker in the Bacterial Cell Division Protein FtsZ, Jessica Louise Bullock

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Dissecting the Roles of Microglial Proteostasis and Innate Immune Signaling in Neurodegeneration, Zhangying Cai

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Piloting a Scalable Workflow to Identify Drivers of Mammalian Aging Using C. Elegans, Ariella Lucia Coler-Reilly Colasanti

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From Bench to Bedside: Unraveling the Role of SARM1 in Chronic Human Neurodegenerative Disease, Caitlin Dingwall

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The Function and Regulation of LAIR1 and LAIR2 in Inflammation and Staphylococcus aureus Infection, Hannah Dorando

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Development of Cell-Free DNA and Immune Cell Liquid Biopsies to Stratify Risk of Disease Progression and Treatment Toxicity, Noah Earland

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Retinal Circuits for Pupil Control: Neural Mechanisms, Visual Functions, and Capacity for Plasticity, Michael John Fitzpatrick

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Elucidating the Coordinated Role of Histone Modifications on the Establishment and Regulation of a Neuronal-specific Methylome, Nicole Hamagami

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Investigating the Intra-host Relationships of the Microbiota at Multiple Sites, Ariel Jose Hernandez-Leyva

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Combined Flt3L and CD40 Agonism Restores Dendritic Cell Driven T Cell Immunity in Mouse Models and Patients With Pancreatic Cancer, Graham Hogg

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Investigating the Regulatory Functions of Long Noncoding RNAs in Retinal Development, Jade Hostetler

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Ribosomal Stress in the Pathogenesis and Treatment of T-cell Acute Lymphoblastic Leukemia, Kimberly Bridget Johansson

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The Role of Autophagy in Intestinal Infection in Mice and C. elegans, Gowri Kalugotla

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Mass Spectrometry Profiling and High-Throughput Sequencing of HDACi-Induced Histone Modification Changes, Rashmi Karki

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A ‘Don’t Eat Too Much’ Signal in Phagocytes via the SIRP⍺-SHP2 Axis Tunes Efferocytosis of Apoptotic Cells, Shannon Kelley

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Reprogramming of Myeloid Cells for Anti-Tumor Immunity, Darya Khantakova

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Targeting the DNMT3B-ABAT Axis in Osteoarthritis Using RNA-peptide Nanoparticles Reveals GABAB Signaling as a Critical Mediator of Articular Chondrocyte Homeostasis, Amir Kucharski

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Learning Sequence Constraints Governing Conformational Ensembles and Function in Intrinsically Disordered Proteins, Jeffrey Lotthammer

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Development and Applications of Optical Imaging Approaches for the Tumor Microenvironment, Megan Suzanne Michie

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Macroevolutionary Innovation and the Genomic Basis of Convergent Adaptation in Anolis Lizards, Aryeh Hershel Miller

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Supporting the next generation: bHLH TF complexes regulating maize anther development, Lily Elizabeth O'Connor

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Molecular Mechanism of WDFY4-Mediated Cross-Presentation by Type 1 Conventional Dendritic Cells, Ray Andrew Ohara

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Molecular Circuits in Dendritic Cell Development, Feiya Ou

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Contextual Coding in the Prefrontal Cortex, Jeong Jun Park

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Spontaneous Blood Oxygen Level Dependent Signals in Glioblastoma-bearing and Aging Brains, Ki Yun Park

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Convergent RNA Pathophysiology in Amyotrophic Lateral Sclerosis, Hunter Lee Patterson

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Synaptic enrichment and diagnostic potential of circular RNA in Alzheimer’s Disease, Bridget Mattie Phillips

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Uncovering Hidden Features of Copyback Viral Genomes, Sarah Pye

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Understanding p53 Regulation on Transposable Elements in Cancer, Xuan Qu

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Astrocyte Circadian Regulation in Neurodegeneration: In Vivo BMAL1 Occupancy Mapping Using MACS-Calling Cards, India Reiss

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Development of a Quantitative Top-Down Proteomics Platform for Arginylated Proteoform Analysis, Richard Myer Searfoss

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Multiplex Functional Assessment of Variant Effect in the Retinal Transcription Factor CRX, James Lewis Shepherdson

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MTHFD2 is a selective metabolic vulnerability in AML, Judith Obiageli Sokei

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Personalized Neoantigen Vaccine-Based Therapies for B-Cell Lymphoma: A Proof-of-Concept Study in Syngeneic Mouse Models of A20 Lymphoma, Yuang Song

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BPTF-Dependent Regulation of Vaccine-Induced B Cell Responses, Alexandria Sturtz

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Beyond Attachment: Endolysosomal Determinants of New World Arenavirus Entry and Fusion, Cassandra E. Thompson

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Bacterial Colonization of Medical Devices in the Urogenital Tract, Morgan Rose Wilt Timm

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Genetic and Observational Insights into Metabolic Alterations in Alzheimer’s Disease, Ciyang Wang

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Unraveling Metabolic Determinants of Isoniazid Susceptibility in Mycobacterium tuberculosis, Erin Rilu Wang

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Energetic Heterogeneity in Retinal Ganglion Cells: Role of Neuronal Activity and Implications for Resilience, Zelun Wang

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Understanding the Biological Functions of Dual-Localized Mitochondrial Phosphatase PPTC7, Lianjie Wei

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Characterization of Ebola Virus VP24-Host Protein Interactions, Junjie Zhao

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Dietary Manipulations of the Undernourished Infant Microbiome, Cyrus Zhou

Theses/Dissertations from 2025

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Montane β-diversity: Biodiversity through Space and Time in Earth’s Most Biodiverse Regions, Ethan Ray Abercrombie

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Mitochondrial Calcium Uniporter Regulates ITAM-Dependent Platelet Activation, Jehiel Abigail Ajanel Gomez

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Exploring DDR2’s role in CAF extracellular matrix production and tumor progression, Favour Ayomide Akinjiyan

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Defining B cell responses to emerging viral pathogens, Wafaa Al Soussi

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Defining B cell responses to emerging viral pathogens, Wafaa Al Soussi

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A Subset of Senescent Myofibroblasts Orchestrates Immunosuppression in Pancreatic Cancer., Jad Belle

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Exploring the Structure, Dynamics, and Pharmacology of Opioid Receptors, Sarah Maria Bernhard

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Single-Cell Analysis of Clonal and Transcriptional Dynamics During Direct Reprogramming, Brent Biddy

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Structure and function of type 1 pilus assembly machinery in uropathogenic Escherichia coli, Ryan Bitter

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Biomarker and age at onset endophenotypes offer new insights into the genetic etiology of Alzheimer’s Disease, Joseph Bradley

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A Mechanistic Exploration of How Neighborhood Crime Exposure Relates to Neonatal Brain Function, Early Externalizing Behaviors, and Callous-Unemotional Traits, Rebecca Brady

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Targeting Cyst(e)ine Dependence and Redox Metabolism in Genetically Distinct Sarcomas, Caitlyn Brook Brashears

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Parapinopsin: a Photoswitchable Inhibitory GPCR for Two-photon Optogenetics, Bobbie J. Brown

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Circuit-specific vulnerability in a mouse model of Alzheimer's Disease, Samuel Brunwasser

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Effects of ANGPTL3 Deficiency on the Regulation of Hepatic Lipoprotein Production and Lipid Metabolism, Kendall Helene Burks

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Targeting Nonsense-Mediated RNA Decay in Splicing Factor Mutant Myeloid Malignancies, Claudia Cabrera

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Dissecting Macrophage Metabolism in Metabolic Liver Disease, Mandy Mei-Ying Chan

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Disrupting NRF2-Driven Cancer Biology through One-Carbon Metabolism Inhibition, Julius Chembo

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A Role for the Actin Cytoskeleton and Plastin-3 in Osteoblast Mineralization and Mechanosensation, Samantha Meagan Chin

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A Role for the Actin Cytoskeleton and Plastin-3 in Osteoblast Mineralization and Mechanosensation, Samantha Meagan Chin

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Diverse Cell Types Establish a Pathogenic Immune Environment in Peripheral Neuropathy, Julie Choi

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Understanding the role of E1OGDH1 in Root System Architecture and Nitrogen Response in Maize, Michelle Sungkyung Cho

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BCLAF1 is a Novel Regulator of Hematopoietic Stem Cells, Stephanie Crowley

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Induced CD8a Identifies Enhanced Human NK cell IL-15-induced Proliferation and Metabolism and Modulates NK cell Activation, Celia Cubitt

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Functional and Structural Connectivity as Predictors of Long-term Motor Development in Very Preterm Children with and without Brain Injury, Peppar Elizabeth Pei-pei Cyr

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Tank to Bedside: How insights from zebrafish inform our understanding of human melanoma drug resistance, Sophia Noah DeGeorgia

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Mutant-Specific Analysis of Tumor Cell Heterogeneity in Glioblastoma, Patrick DeSouza

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Understanding Strain-level Dynamics in Gut Commensal-Pathogen-Host Interactions, Anna Louise DeVeaux

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APOBEC3A Promotes the Metastatic Progression of High-grade Serous Ovarian Carcinoma by Altering Epithelial-mesenchymal Trajectories, Jessica Merritt Devenport

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Emergence and Evolution of Antibiotic Resistance in the Built Environment, Luke Diorio-Toth

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Sex, Stress and Hormones : The Role of Modifiable Risk Factors in the Kinetics of Alzheimer’s Disease, Hannah Marie Edwards

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The Role of the cGAS-STING Sensing Pathway in HIV-1 and SARS-CoV-2 Infections, Jenna Eve Eschbach

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Understanding host-pathogen interactions using the Caenorhabditis elegans – Orsay virus experimental model, Chika Fujii

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Characterizing PIEZO1 Mechanotransduction in Articular Chondrocytes, Jaquelin Marlen Garcia Castorena

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Roles of CpsA and SLAMF1 in the innate immune response to Mycobacterium tuberculosis, Steven Grigsby

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Biophysical insights into emerging virus-host interactions, Paige Danielle Hall

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Parsing Heterogeneity in Depression, Kayla Hannon

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JARID2-mediated Reprogramming of Human Hematopoietic Progenitors for Stem Cell Transplantation, Wentao Han

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Computational and mathematical modeling of microbial community and host responses to microbiota-directed complementary foods administered to children with acute malnutrition., Steven J. Hartman

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DNA-damaging chemotherapy reshapes the immune landscape of the heart, Ruijun He

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Barriers and Breakthroughs in the Evolution of Aggregative Multicellularity, Israt Jahan

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Barriers and Breakthroughs in the Evolution of Aggregative Multicellularity, Israt Jahan

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Novel Therapeutics for Alzheimer's Disease, Nimansha Jain

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Lysosomes as Gatekeepers: How LIC1-Mediated Trafficking Regulates Angiogenesis and Vascular Morphogenesis, Dymonn Johnson

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Multiclass Liquid Biopsy Assessment of Neurofibromatosis Type 1 Associated Nerve Sheath Tumors, Paul Andrew Jones

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Defining the Roles of cDCs in Antigen Presentation: from Tumor to mRNA Vaccines, Suin Jo

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Functional Diversification of Rice AGO1 Proteins, Rachel Elie Jouni

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Mechanisms of Protective Humoral Immunity and Pathogenesis in Alphavirus Infection, Natasha Monir Kafai

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Examing the Role of Complement Signaling in Viral Neuroinflammatory Responses, Marlene Kanmogne