Theses/Dissertations from 2018
Glucose Transporters in Hepatic Fasting Metabolism: Implications for Cardiometabolic Disease, Allyson Leigh Mayer
Defining Neuronal Identity Using MicroRNA-Mediated Reprogramming, Matthew James Mccoy
Tumors Interrupt IRF8-Mediated Dendritic Cell Development to Overcome Immune Surveillance, Melissa Ann Meyer
Targeting the Microenvironment: Approaches for Reducing Breast Cancer Metastases and Chemotherapy-induced Bone Loss, Bhavna Murali
Sex Differences in Uropathogenic Escherichia coli Urinary Tract Infection, Patrick David Olson
Ushering CUP Pilus Assembly: Dissecting the Mechanics of a Bacterial Nanomachine, Natalie Saranga Omattage
Regulation of Local Translation in Neuronal Processes of Specific Cell Types, Rebecca Ouwenga
Methods to Record Transcription Factor Binding and Enhancer Activity throughout Cellular Differentiation, Zongtai Qi
Characterization of the CELF6 RNA Binding Protein: Effects on Mouse Vocal Behavior and Biochemical Function, Michael A. Rieger
Innate Lymphoid Cells: Transcriptional Profiles and Cytokine Developmental Requirements, Michelle Lauren Robinette
Bone-Induced Expression of Tumoral Integrin β3 Enables Targeted Nanotherapy of Breast Cancer Metastases, Michael H. Ross
Deciphering mechanisms governing the development of the rod epigenome, Philip Andrew Ruzycki
Local Translation in Peripheral Astrocyte Processes, Kristina Sakers
Forward and Reverse Genetic Approaches to Understanding Myelination, Nicholas Enrique Sanchez
Breath biomarkers and an expanded role for isoprenoids in Plasmodium falciparum, Chad Louis Schaber
Regulation of Epithelial Proliferation and Migration by Apical-Basal Polarity Proteins, Gregory Vincent Schimizzi
Smooth as SILK: Translating Discoveries to New Therapies in Amyotrophic Lateral Sclerosis, Wade Self
Protein Structure-Guided Approaches to Identify Functional Mutations in Cancer, Sohini Sengupta
Tau monomer encodes Strains, Apurwa Sharma
Novel Approaches to Studying the Effects of Cis-Regulatory Variants in the Central Nervous System, Susan Shen
Understanding Stroke in the Connected Human Brain, Joshua Sarfaty Siegel
Roles of ESCRT machinery in endosomal repair and recycling, Michal Leszek Skowyra
Circadian Regulation of Temozolomide Sensitivity in Glioblastoma, Emily A. Slat
The Role of NFκB in the Pathogenesis of Myeloproliferative Neoplasms, Steven C. Snyder
Characterizing the Role of the T Cell Receptor Repertoire in T Cell Development and Function, Benjamin David Solomon
Adenoviral Delivery of CRISPR/Cas9 for Gene Editing-based Gene Therapy of Hemophilia B, Calvin Stephens
The Costs of a Big Brain: How Region Scaling and Energetic Costs Influence Brain Size Evolution in Weakly Electric African Fishes (Mormyridae), Kimberley Varunee Sukhum
Development and Function of Retinal Ganglion Cell Circuits, Nai-Wen Tien
Astrocytes Regulate Daily Rhythms in the Suprachiasmatic Nucleus (SCN) and Behavior, Chak Foon Tso
Molecular Mediators of Acute and Chronic Itch in Mouse and Human Sensory Neurons, Manouela Valtcheva
Kinetic Modeling of RNA Folding and Allostery, Robb Welty
Functions of the Novel Molecule LysMD3 in Mice and Flies, Christine Chieko Yokoyama
A Recombinant Virus and Reporter Mouse System to Study Chronic Chikungunya Virus Pathogenesis, Alissa Roxanne Young
Discovering Rare Hematopoietic Clones Harboring Leukemia-Associated Mutations Using Error-Corrected Sequencing, Andrew Lee Young
Transcriptional Signatures of Host Susceptibility in Urinary Tract Infections, Lu Yu
The Role of Mesenchymal Stromal Cells and Classical Dendritic Cells in the Maintenance and Regulation of the Bone Marrow Niche, Jingzhu Zhang
Theses/Dissertations from 2017
Brain Enriched microRNAs Open the Neurogenic Potential of Adult Human Fibroblasts, Daniel Gene Abernathy
Understanding the Relationship Between Hosts and their Microbiome, Boahemaa Adu-Oppong
Knowledge Driven Approaches and Machine Learning Improve the Identification of Clinically Relevant Somatic Mutations in Cancer Genomics, Benjamin John Ainscough
Mechanism of Gene Regulation by Coding PolyA Tracks, Laura Lea Arthur
Mitochondrial damage accumulation in oocytes – a potential link between maternal obesity and increased cardiometabolic disease risk in offspring., Anna Louise Boudoures
The Role of RNA Interference in the Control of Leishmania RNA virus 1 Infection, Erin Acino Brettmann
Mitochondrial Dynamics Controls T Cell Fate Through Metabolic Programming, Michael Buck
Quantitative profiling of cooperative transcription factors pairing on hundreds of sequences in parallel, Yiming Chang
Regulation of Early Zebrafish Embryogenesis by Calcium Signaling and Dachsous1b Cadherin, Jiakun Chen
Exploring Host-Virus Interactions in Caenorhabditis Nematodes, Kevin Chen
Regulation of gene expression by RNA binding proteins and microRNAs, Kyle Cottrell
Characterization of ZIP genes responsible for zinc homeostasis in C. elegans, Nicholas Dietrich
Hepatic Ketogenesis as a Novel Regulator of Liver Metabolism and Injury, Baris Can Ercal
Characterization and Function of Islet Antigen Presenting Cells during NOD Diabetes, Stephen Thomas Ferris
Regulation of the Pro-Tumorigenic Senescence-Associated Secretory Phenotype, Kevin Flanagan
Roles of Peroxisomes and Peroxisome-Derived Products in Controlling Plant Growth and Stress Responses, Elizabeth May Frick
Recent Positive Selection of the Epidermal Differentiation Complex in Mammals, Primates, and Humans, Zane Alexander Goodwin
Flaviviruses: Innate Immune Restriction and Host Adaptation, Matthew Joseph Gorman
Genetic and genomic dissections of myelinating glial cell development, Breanne Leigh Harty
The RpL13a snoRNA U33 Forms Novel snoRNPs During Lipotoxicity, Miquia Sherree Henderson
The Regulation of Extracellular Amyloid-β Levels by Ionotropic Glutamatergic Transmission in an Alzheimer’s Disease Mouse Model, Jane Cecelia Hettinger
Sequence Determinants of the Individual and Collective Behaviour of Intrinsically Disordered Proteins, Alexander S. Holehouse
Analysis of Argonaute-Small RNA-Transcription Factor Circuits Controlling Leaf Development, John Steen Hoyer
Epigenetic Regulation of Lymphocyte Development and Transformation, Yue Huang
Specificity Determination by paralogous winged helix-turn-helix transcription factors, Adam Joyce
Mechanisms of G Protein Regulation by RGS Proteins and Small Molecule Inhibitors, Stanley Michinobu Kanai
Factors that Contribute to de novo Protein Misfolding and Prion Formation in Saccharomyces cerevisiae, Kathryn Morgan Keefer
The Effect of Dietary Fat on Obesity, Gene Expression, and DNA Methylation in Two Generations of Mice, Madeline Rose Keleher
Motion processing in the mouse retina, Tahnbee Kim
Structural, Biophysical, and Functional Studies of TREM2 In Neurodegenerative Disease, Daniel L. Kober
Targeting the Response to Arginine Starvation in ASS1-Deficient Sarcomas, Jeff Kremer
Expansion of Microbial Virology by Impetus of the Reduction of Viral Dark Matter, Siddharth Ravindran Krishnamurthy
Glucose Metabolism in Plasma Cell Populations in the Bone Marrow and Spleen, Wing Yu Lam
Functional Brain Organization in Space and Time, Timothy Laumann
Epigenome Dynamics in Vertebrate Development and Regeneration, Hyung Joo Lee
Nuclear export factor 3 regulates the localization of small nucleolar RNAs, Melissa Wanling Li
The Role of Bhlhe40 in Autoimmune Neuroinflammation and Mycobacterial Infection, Chih-Chung Lin
Metabolic Modulation of Bacterial Resistance to Alpha-Defensins, Christine Tzy-Yuh Luo
Discovery and Characterization of Rv0004 as a Novel and Essential Part of the Mycobacterial DNA Replication Machinery, Katherine Mann
The Role of VIP SCN Neurons in Circadian Physiology and Behavior, Cristina Mazuski
Designing Epigenome Editing Tools to Understand the Functional Role of DNA Methylation Changes in Cancer, James Mcdonald
Beta-Diversity Patterns and Community Assembly across Latitudes, Emma Moran
The Development and Characterization of New Models of Recurrent Urinary Tract Infection, Valerie Phoebe O'brien
Novel Insights into Yersiniabactin Biosynthesis in Uropathogenic Escherichia coli, Shannon Ileen Ohlemacher
The Role of Histidine Rich Protein II in Cerebral Malaria, Priya Pal
DNA Replication Challenges: Telomeres and R loops, Shankar Parajuli
Mechanisms and Regulation of Resection in DNA Damage Response, Sharad C. Paudyal
Identification and Characterization of an Interferon Stimulated Gene That Restricts Alphavirus Infection and Pathogenesis, Subhajit Poddar
Metabolic regulation of CD8 T cell functions in the tumor microenvironment, Jing Qiu
Antiviral Nucleoside Inhibitors of Leishmania RNA Virus 1: Discovery and Mechanism, John Isaac Robinson
Identification of Novel Variants Associated with Alzheimer’s Disease Using Quantitative Traits, Yuetiva Karenina Robles
A Generalized Biophysical Model of Transcription Factor Binding Specificity and Its Application on High-Throughput SELEX Data, Shuxiang Ruan
Determining the Molecular Mechanisms of Huntington’s Disease through Multi-Scale Modeling, Kiersten Ruff
Biophysical studies of the intracellular domains of the EGFR family of Receptor Tyrosine Kinases, Kwabena A N Sarpong
Modeling Complex Patterns of Differential DNA Methylation That Associate with Expression Change, Christopher E. Schlosberg
Understanding the paradox of genetic diversity in uropathogenic E. coli: the uncommon evolution of a common pathogen, Henry Louis Schreiber
The Effects of the Gut Microbiota on the Host Chromatin Landscape, Nicholas Semenkovich
Bridging the translational gap between rodent and human pain research, Tayler Diane Sheahan
Investigation of the Contribution of Type 1 Pili in Enterotoxigenic Escherichia Coli (ETEC) Pathogen-Host Interactions, Alaullah Sheikh