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Theses/Dissertations from 2015

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The Collagen Receptor Discoidin Domain Receptor 2 is Critical for Breast Cancer Metastasis, Callie Corsa

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Ketone Body Metabolism Preserves Hepatic Function during Adaptation to Birth and in Overnutrition, David Graham Cotter

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Contributions of the Endoplasmic Reticulum Stress Response to Glioblastoma Cell Viability, David Yaw Amoah Dadey

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Host Immune Signals Regulate Blood-Brain Barrier Function During Central Nervous System Infection and Autoimmunity, Brian Daniels

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Defining the Roles of Outer Membrane Proteins and Host Cathelicidins in Uropathogenic Escherichia coli Infection, Elizabeth Sarah Danka

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The Role of Tmem178 in Regulation of Osteo-Immune Activation and Inflammatory Bone Loss, Corinne Elaine Decker

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High-throughput 2-hydroxyglutarate Assays for Biological Screening in IDH Mutant Cells, Adnan Elhammali

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Complex Genome Regulation Characterized by Atypical Signatures in DNA Methylation, GiNell Elliott

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Functional Identification and Characterization of cis-Regulatory Elements, Christopher Michael Fiore

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Mechanisms of Cell-Autonomous Immunity to Toxoplasma gondii, Elizabeth Mae Selleck Fiore

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A Novel Cholesterol-Independent Mode of Binding Promotes Cytolysin-Mediated Translocation and Pore Formation by Streptolysin O, Cara Mozola Forsberg

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The Diversity, Ecology, and Clinical Implications of Antibiotic Resistance Genes in Uncultured Soil Microbial Communities, Kevin J. Forsberg

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Role of the Flagellum Throughout the Leishmania Life Cycle, Tiffanie Janae Fowlkes

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Characterizing and Modeling Antibiotic Resistance Dynamics in Diverse Microbial Communities, Molly Krisann Gibson

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Programming the Myocardium: the Notch-Wnt Axis, Benjamin S. Gillers

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Assessing Vascular Inflammation with Bioluminescence Imaging, Reece Joseph Goiffon

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Dissemination, Suppression, and Evolution of Antibiotic Resistance in Human Pathogens, Patrick Rolland Gonzales

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Variation and Plasticity of DNA Methylation in Genome Regulation, Junchen Gu

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Evolutionary Developmental Leaf Morphology of the Plant Family Araceae, Claudia Liliana Henriquez

Gene Expression and Enhancer Discovery in the Neural Crest, Charles Higdon

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Melittin-Derived Peptides for siRNA Delivery: Mechanisms of Efficient Cytoplasmic Release, Kirk Kohwa Hou

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The Attentional Control of Reading: Insights from Behavior, Imaging and Development, Sarah Ihnen

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Molecular and Epigenetic Regulation of Stem Cell Radiosensitivity, Keith Michael Jacobs

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The Roles of MIST1 and RAB26 in Zymogenic (Chief) Cell Differentiation and Subcellular Organization, Ramon Jin

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The Role of Myc and AP-1 Transcription Factors in the Development and Function of the Dendritic Cell Lineage, Wumesh K.C.

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The Identification of Alkaloid Pathway Genes from Non-Model Plant Species in the Amaryllidaceae, Matthew B. Kilgore

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Investigating Auxin Signaling Through AUXIN RESPONSE FACTOR Interactions and Stability, David Korasick

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Guanine Nucleotide Synthesis and The Enteric Nervous System, Jonathan Ian Lake

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Neural Basis of Functional Connectivity MRI, Jingfeng Li

The Role of BMP Signaling in Embryonic Limb Development and Postnatal Bone Formation, Joohyun Lim

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Atypical Cadherin Dachsous Regulates The Cytoskeleton And Gastrulation Movements During Zebrafish Development, Nanbing Li

Cell-Size Control in Chlamydomonas reinhardtii, Dianyi Liu

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BNIP3 Phosphorylation is a Switch that Regulates Autophagy and Cell Death, Katherine Liu

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Essential Roles of Stat3 in Zebrafish Development, Yinzi Liu

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The Intrinsic Apoptotic Cascade in Hematopoiesis and Susceptibility to Therapy-Related Leukemia, Elise Peterson Lu

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How Gains and Losses Influence the Brain and Behavior: Relations to Age, Risk for Depression, and Individual Differences, Katherine R. Luking

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Spatial and Epigenetic Regulation of T-Cell Receptor Beta Gene Assembly, Kinjal Majumder

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The Role of Reversible Palmitoylation in Regulating Diverse Biological Processes, Mohammad H. Maktabi

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Molecular Mechanisms of Plasmodium Red Blood Cell Invasion, Brian Michael Malpede

Mechanisms for Colonic Mucosal Wound Repair, Nicholas Andrew Manieri

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Dissection of Affective Catecholamine Circuits Using Traditional and Wireless Optogenetics, Jordan Gary McCall

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Molecular and Computational Methods for Cellular State Control, Drew Groves Michael

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Endogenous Protection in Subarachnoid Hemorrhage, Eric Milner

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Transcriptional Regulation of the Endoplasmic Reticulum in Dedicated Secretory Cells, Benjamin David Moore

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Spinal k-Opioid Receptor Activation Attenuates Itch by Inhibiting Gastrin-releasing Peptide Receptor Function, Admire Munanairi

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Behavioral and fMRI-based Characterization of Cognitive Processes Supporting Learning and Retrieval of Memory for Words in Young Adults, Binyam Nardos

Molecular Basis of the Biogenesis and Function of the Enterococcus faecalis Endocarditis- and Biofilm-Assiciated Pilus, Hailyn Nielsen

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Characterizing Regulatory T Cell Differentiation to Bacterial Antigens in the Gut, Katherine Nutsch

HIV Neurodegeneration in the HAART Era, Mario Ortega

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The Effects of HPA Axis Genetic Variation and Early Life Stress on Cortisol Levels in Preschool Age Children and on Amygdala and Hippocampus Volumes, Reactivity, and Connectivity at School Age, David Pagliaccio

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Molecular Characterization of a Novel, Highly Protective Combination Monoclonal Antibody Therapy against Chikungunya Virus, Pankaj Pal

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Adaptive Mechanisms of Niche Remodeling in Streptococcus pyogenes, Elyse Paluscio

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Neural Mechanisms of Working Memory Cortical Networks, Charalampos Papadimitriou

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Distribution and Dissemination of Antibiotic Resistance Genes between Microbiota in Antibiotic-Naïve and Resource-Poor Settings, Erica Courtney Pehrsson

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Functional Consequences of CD4+ T Cell Receptor Ligation in the Immune Response to Listeria monocytogenes, Stephen Phillip Persaud

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β-Lactamase Gene Exchange within the Enterobacteriaceae, Mitchell William Pesesky

Differential Encoding of Spatial Information among Retinal ON Cone Bipolar Cells, Robert Joseph Purgert

Characterizing Rare Genetic and Epigenetic Variation in Complex Phenotypes, Enrique Ivan Ramos

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DNA Damage Responses Regulate Macrophage Function During Innate Immune Responses, Abigail Rodriguez Morales

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Viral and Innate Immune Factors Controlling Disease Susceptibility During Chikungunya Virus Infection, Anjali Rohatgi

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Senescent Fibroblasts Drive Tumorigenesis Through the Establishment of an Immunosuppressive Microenvironment, Megan Kiel Ruhland

Habitat Size Mediates the Effects of Environmental Factors on Species Richness, Matthew Scott Schuler

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Understanding Escherichia coli Urinary Tract Infection: A Niche Perspective, Drew Joel Schwartz

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Escherichia coli Iron Acquisition Paradigms and Host Responses in the Human Urinary Milieu, Robin Reid Shields-Cutler

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Functional Characterization of Putative Rab Geranylgeranyltransferase Subunits in Arabidopsis thaliana, Wan Shi

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Dissecting Intracellular Signaling and Affective Behavior Using Optically Active GPCRs, Edward Ryszard Siuda

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Identifying the Functions of ILC3 in Intestinal Immunity, Christina Song

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Mitochondrial Dynamism and Mitochondrial Quality Control in the Heart, Moshi Song

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Impaired Gut Microbial Community Development in Undernourished Children, Sathish Subramanian

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Flap Endonuclease 1 Promotes Telomere Replication and Stability by Distinct Mechanisms on the Leading and Lagging Strands, Daniel Cole Teasley

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Excessive Complement Activation Due to Genetic Haploinsufficiency of Regulators in Multiple Human Diseases, Michael Triebwasser

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Transmission Dynamics of Antibiotic Resistance Genes Between Human-associated and Environmental Microbial Communities, Pablo Tsukayama

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Mechanisms Underlying Memory Deficits Following West Nile Virus Neuroinvasive Disease, Michael John Vasek

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A Gnotobiotic Mouse Model for Studying the Effect of Human Gut Community Ecology on a Pathobiont, Bacteroides fragilis, Vitas Wagner

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BTB-ZF Regulators of Long-Term Antibody Responses, Yinan Wang

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Mechanisms of High Zinc Tolerance, Sensing, and Homeostasis in C. elegans, Kurt Warnhoff

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Single-chain RANKL Provides Insights into RANK Receptor Oligomerization and a Novel Approach to Osteoclast Inhibition, Julia Therese Warren

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Molecular Mechanisms of Axon Growth and Regeneration, Dana Watt

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The U1A/U2B"/SNF Family of RNA Binding Proteins: Evolution of RNA Binding Specificity and Contributions of Heterotropic Linkage to snRNP Protein Partitioning, Sandra Gisela Williams

Retinoids and Mitochondrial Effects on Enteric Nervous System Development, Structure, and Function, Elizabeth Copeland Wright-Jin

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Factors Contributing to Yeast Prion Generation and Propagation, Siyao Xing

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The Mechanism and Regulation of Mammalian Photoreceptor Dark Adaptation, Yunlu Xue

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Genetic and Cellular Studies of The Podocyte in Focal Segmental Glomerulosclerosis, Haiyang Yu

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Human Immunodeficiency Virus Type 1 Envelope Protein Interaction with Host Cell Coreceptor C-X-C Chemokine Receptor Type 4, Jie Zhang

Theses/Dissertations from 2014

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Novel Role of CHK2 in the Intrinsic and Extrinsic Apoptosis Pathway, Anurag Agarwal

The Role of GRA7, a Component in the ROP18 Protein Complex, in Toxoplasma gondii, Aditi Alaganan

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Contribution of the Microenvironment in Bone Resident Cancer: the Role of Thrombospondin-1 in Bone and Risk Loci Contributing to Multiple Myeloma, Sarah R. Amend

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Genetic and Epigenetic Determinants of Transcription in the Divergent Eukaryote Leishmania major, Britta Anderson

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Failsafe Mechanisms Coordinate Cell Division and the Initiation of DNA Replication in Bacteria, Heidi Ann Arjes

Genetic Architecture of Left Ventricular Hypertrophy, Ruteja A. Barve

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Modulating Amyloid Beta Clearance by Altering Cellular and Whole Brain Apolipoprotein E Metabolism, Jacob Martin Basak

Defining the Peripheral and Thymic Niche of Regulatory T Cells, Jhoanne Lynne Bautista

PUMA and BIM Are Required for Oncogene Inactivation-Induced Apoptosis and Anoikis, Gregory Bean

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Dynamic Responses at the Barrier Epithelium, Katherine Beebe

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Axonal Damage in Repetitive Concussive Traumatic Brain Injury: Characterization and Contributing Factors, Rachel Bennett

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Oxygen Polarography in the Awake Macaque: Bridging BOLD fMRI and Electrophysiology, William Joseph Bentley

The Role of Oxysterol-Membrane Effects on Cholesterol Activity and Homeostasis, Agata Agnieszka Bielska

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Strategies for Computational Protein Design with Application to the Development of a Biomolecular Tool-kit for Single Molecule Protein Sequencing, Benjamin Borgo

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Transcriptional Analysis of Reciprocal Tumor-Microenvironment Interactions in Glioblastoma, Michael Brooks

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Genomic Analysis of Human Spinal Deformity and Characterization of a Zebrafish Disease Model, Jillian Gwen Buchan