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Theses/Dissertations from 2017

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Regulation of the Pro-Tumorigenic Senescence-Associated Secretory Phenotype, Kevin Flanagan

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Roles of Peroxisomes and Peroxisome-Derived Products in Controlling Plant Growth and Stress Responses, Elizabeth May Frick

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Recent Positive Selection of the Epidermal Differentiation Complex in Mammals, Primates, and Humans, Zane Alexander Goodwin

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Flaviviruses: Innate Immune Restriction and Host Adaptation, Matthew Joseph Gorman

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Genetic and genomic dissections of myelinating glial cell development, Breanne Leigh Harty

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The RpL13a snoRNA U33 Forms Novel snoRNPs During Lipotoxicity, Miquia Sherree Henderson

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The Regulation of Extracellular Amyloid-β Levels by Ionotropic Glutamatergic Transmission in an Alzheimer’s Disease Mouse Model, Jane Cecelia Hettinger

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Sequence Determinants of the Individual and Collective Behaviour of Intrinsically Disordered Proteins, Alexander S. Holehouse

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Analysis of Argonaute-Small RNA-Transcription Factor Circuits Controlling Leaf Development, John Steen Hoyer

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Epigenetic Regulation of Lymphocyte Development and Transformation, Yue Huang

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Structure, function, and antibody-mediated inhibition of Plasmodium CelTOS, a protein that enables cell traversal by malaria parasites, John Jimah

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Specificity Determination by paralogous winged helix-turn-helix transcription factors, Adam Joyce

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Mechanisms of G Protein Regulation by RGS Proteins and Small Molecule Inhibitors, Stanley Michinobu Kanai

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Factors that Contribute to de novo Protein Misfolding and Prion Formation in Saccharomyces cerevisiae, Kathryn Morgan Keefer

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The Effect of Dietary Fat on Obesity, Gene Expression, and DNA Methylation in Two Generations of Mice, Madeline Rose Keleher

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Motion processing in the mouse retina, Tahnbee Kim

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Structural, Biophysical, and Functional Studies of TREM2 In Neurodegenerative Disease, Daniel L. Kober

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Targeting the Response to Arginine Starvation in ASS1-Deficient Sarcomas, Jeff Kremer

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Expansion of Microbial Virology by Impetus of the Reduction of Viral Dark Matter, Siddharth Ravindran Krishnamurthy

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Glucose Metabolism in Plasma Cell Populations in the Bone Marrow and Spleen, Wing Yu Lam

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Functional Brain Organization in Space and Time, Timothy Laumann

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Epigenome Dynamics in Vertebrate Development and Regeneration, Hyung Joo Lee

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Nuclear export factor 3 regulates the localization of small nucleolar RNAs, Melissa Wanling Li

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The Role of Bhlhe40 in Autoimmune Neuroinflammation and Mycobacterial Infection, Chih-Chung Lin

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Metabolic Modulation of Bacterial Resistance to Alpha-Defensins, Christine Tzy-Yuh Luo

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Discovery and Characterization of Rv0004 as a Novel and Essential Part of the Mycobacterial DNA Replication Machinery, Katherine Mann

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The Role of VIP SCN Neurons in Circadian Physiology and Behavior, Cristina Mazuski

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Designing Epigenome Editing Tools to Understand the Functional Role of DNA Methylation Changes in Cancer, James Mcdonald

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Beta-Diversity Patterns and Community Assembly across Latitudes, Emma Moran

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The Development and Characterization of New Models of Recurrent Urinary Tract Infection, Valerie Phoebe O'brien

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Novel Insights into Yersiniabactin Biosynthesis in Uropathogenic Escherichia coli, Shannon Ileen Ohlemacher

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The Role of Histidine Rich Protein II in Cerebral Malaria, Priya Pal

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DNA Replication Challenges: Telomeres and R loops, Shankar Parajuli

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Mechanisms and Regulation of Resection in DNA Damage Response, Sharad C. Paudyal

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Bacterial Targets of Gut Mucosal Immunoglobulin A Responses in Healthy and Undernourished Children, and in Gnotobiotic Mice Colonized with Human Gut Microbiota, Joseph Planer

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Identification and Characterization of an Interferon Stimulated Gene That Restricts Alphavirus Infection and Pathogenesis, Subhajit Poddar

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Metabolic regulation of CD8 T cell functions in the tumor microenvironment, Jing Qiu

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Antiviral Nucleoside Inhibitors of Leishmania RNA Virus 1: Discovery and Mechanism, John Isaac Robinson

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Identification of Novel Variants Associated with Alzheimer’s Disease Using Quantitative Traits, Yuetiva Karenina Robles

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A Generalized Biophysical Model of Transcription Factor Binding Specificity and Its Application on High-Throughput SELEX Data, Shuxiang Ruan

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Determining the Molecular Mechanisms of Huntington’s Disease through Multi-Scale Modeling, Kiersten Ruff

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Biophysical studies of the intracellular domains of the EGFR family of Receptor Tyrosine Kinases, Kwabena A N Sarpong

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Modeling Complex Patterns of Differential DNA Methylation That Associate with Expression Change, Christopher E. Schlosberg

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Understanding the paradox of genetic diversity in uropathogenic E. coli: the uncommon evolution of a common pathogen, Henry Louis Schreiber

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The Effects of the Gut Microbiota on the Host Chromatin Landscape, Nicholas Semenkovich

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Bridging the translational gap between rodent and human pain research, Tayler Diane Sheahan

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Investigation of the Contribution of Type 1 Pili in Enterotoxigenic Escherichia Coli (ETEC) Pathogen-Host Interactions, Alaullah Sheikh

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Investigating the Role of GH3 Acyl Acid Amido Synthetases in Plant Hormone Homeostasis, Ashley Marie Sherp

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Robust Algorithms for Detecting Hidden Structure in Biological Data, Roman Sloutsky

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Type 1 and F17-like Pili Promote the Establishment of the Uropathogenic E. coli Intestinal Reservoir, Caitlin Nicole Spaulding

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Longitudinal Cerebrospinal Fluid Biomarkers of Alzheimer Disease: Movement Toward the Diagnosis, Prognosis and Staging of Disease, Courtney Sutphen

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Modeling Huntington's Disease With Neurons Directly Converted from Patient Fibroblasts, Matheus B. Victor

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Influenza A virus Genomic Reassortment and Packaging, Graham Devin Williams

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Epigenetic Activation of the Mouse T Cell Receptor Beta Recombination Center, Jiangyang Zhao

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Defining the Ontogeny and Functions of Macrophages in Pancreatic Ductal Adenocarcinoma, Yu Zhu

Theses/Dissertations from 2016

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Mechanisms of Myelination, It's All About the Matrix, Sarah Degenova Ackerman

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Circuit Mechanisms of Spontaneous and Light Evoked Activity in the Retina, Alejandro Akrouh

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Health Implications of Excess Fructose Consumption and Increased Risk for Offspring Diseases, Zeenat Afshan Asghar

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Engineering Escherichia coli towards the production of branched-chain advanced biofuels, Gayle Joann Bentley

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Action of SNAIL1 Protein is Critical for Fibrosis, Hirak Biswas

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Disrupted Gut Microbiota Development and Childhood Undernutrition, Laura Vanarendonk Blanton

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The Molecular and Cellular Basis for Cold Sensation, Daniel Brenner

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Developmentally Imprinted Gamma-Delta T Cells Provice IL-17A in Acute Defense Against Clostridium difficile Infection, Y.S. Chen

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Regulation of durable adaptive immune response by the c-MYC-AP4 transcriptional cascade, Chun Chou

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The Role of DNMT3A in Acute Myeloid Leukemia Pathogenesis, Christopher Browning Cole

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Characterization of Salivary Gland Innate Lymphoid Cells, Victor Samuel Cortez

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Superoxide Dismutase 1: Novel Insights on Disease Models and Tissue Specificity in Amyotrophic Lateral Sclerosis, Matthew James Crisp

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Granulocyte-Colony Stimulating Factor Reprograms the Bone Marrow Microenvironment to Suppress B Lymphopoiesis, Ryan Brent Day

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Population Structure and Mating Dynamics in the Social Amoeba Dictyostelium discoideum, Tracy Edwards Douglas

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New Regulators of Auxin Response Reveal Insights into Cell Expansion, Tara Ann Enders

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Mitochondrial Transport and Function in Development and Disease, Michelle Faits

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The Resolution Phase of NK Cell Proliferation and IFN Production Following Viral Infection Are Highly Regulated Processes., Leslie Abigail Fogel

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Regulation of Transcription and Stress Response by CarD in Mycobacteria, Ashley Louise Garner

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Molecular Studies of SARM1, an Axonal Self-Destruction Switch, Josiah Gerdts

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Regulation and Inhibition of Uropathogenic E. coli Extracellular Appendages, Sarah Elizabeth Greene

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Ecological and Genetic Consequences of Climate Change Impacting Species Distributions, with Specific Cases in Whitebark Pine (Pinus albicaulis Engelm.), Jennifer A. Gruhn

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Discovery and characterization of a novel class of metabolic regulators in the malaria parasite Plasmodium falciparum, Ann Marie Guggisberg

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The Murine Accessory Olfactory Bulb as a Model Chemosensory System: Experimental and Computational Analysis of Chemosensory Representations, Gary Francis Hammen

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Molecular Mechanisms Mediating the Effects of Acute Dietary Vitamin A Deficiency on a Defined Model Human Gut Microbiota, Matthew Charles Hibberd

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The Maintenance of Age in Reprogrammed Human Neurons, Christine Jean Huh

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Targeting Isoprenoid Biosynthesis in Plasmodium falciparum, Leah Imlay

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Mechanisms of Extracellular Vesicle Biogenesis, Charles Eldon Jackson

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Differential Associations of Stress and Cortisol with Brain Structure and Cognition in Cognitively Normal Older Adults, Ana Kim

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Characterization of autophagy-dependent and independent roles of ATG5 in controlling Mycobacterium tuberculosis infection, Jacqueline M. Kimmey

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Structure-Function Analysis of Blue Copper Proteins, Jeremy D. King

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Metal Selectivity and Acquisition by the Yersiniabactin Metallophore System in Escherichia coli, Eun-Ik Koh

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Modulation of Human and Malarial Glucose Transporter Activity by Lipids and Small Molecules, Thomas E. Kraft

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Epigenomics of Cell Fate in Development and Disease, Rebecca Faith Lowdon

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Structure, Dynamics, and Regulation of Collective Cell Migration, Andrew J. Loza

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A study of local and regional gene regulatory features in the human genome, Brett Maricque

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Investigating auxin biosynthesis and its contribution to virulence by Pseudomonas syringae pv tomato DC3000, Sheri Mcclerklin

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Functions for Murine Norovirus Protein NS1/2 in Mice and Cells, Broc Taylor Mccune

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The p38MAPK-MK2-HSP27 axis regulates the mRNA stability of the pro-tumorigenic senescence-associated secretory phenotype, Hayley Reynolds Moore

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Genetic Mechanisms for the Maintenance of Behavioral Mating Barriers in Drosophila, Kathleen M. Mortland

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Use of Proteomics to Probe Dynamic Changes in Cyanobacteria, Amelia Yen Nguyen

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Novel regulation of the nonsense-mediated RNA decay pathway, Andrew Keith Nickless

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The Role of Epidermal Enhancer 923 in the Chromatin Architecture and Transcriptional Regulation of the Epidermal Differentiation Complex, Inez Oh

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Refining Associations between Targeted Genes and the Development of Substance Use Disorders, Emily Olfson

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Iron Regulation of Macrophage Responses to Uropathogenic E. coli, Nana Kwame Owusu-Boaitey

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Antimicrobial Resistance and Structure-Guided Drug Development, Jooyoung Park