Theses/Dissertations from 2024
Mechanisms of uropathogenic E. coli reservoir formation in the gastrointestinal tract, Philippe Nimma Azimzadeh
Interleukin-1α and Leukemia Inhibitory Factor Promote Cancer-Induced Extramedullary Hematopoiesis, Derek Arthur George Barisas
Inducible CRISPR-Targeted ‘Knockdown’ of Human Gut Bacteroides in Mice Reveals Glycan Utilization Strategies, Zachary Beller
Development and Structure of Spinal Interneuron Connectivity in Larval Zebrafish, Saul Bello Rojas
Evaluating Pathological Tau Spread in Early Alzheimer Disease: Developing a Metric for Tau Positron Emission Tomography Quantifying Tau Spatial Spread, Stephanie Sierra Doering
Characterizing the Causal Role of SVEP1 in Human Disease, Jared S. Elenbaas
Dimerization of the Fluoride Channel Fluc in Membranes, Melanie Ernst
Tracking and Mitigating Imprint Erasure During Human Pluripotent State Transitions, Laura A. Fischer
Applications of Bioinformatics for Exploring the Genomic Landscape of Cancer and Characterizing Treatment Response for Precision Oncology, Sharon Freshour
The Cell Biology of Cryptococcal Capsule Production, Elizabeth Gaylord
Leveraging Microbes to Improve Cancer Outcomes, Olivia Nicole Gorushi
A Test of the Pioneer Factor Hypothesis for Silent Gene Activation, Jeffrey Hansen
Vascular Electrophysiology and Pathogenic Consequences of Cardiovascular KATP Channel Mutations, Alex Hanson
Treatment Modifications and Development for Mucopolysaccharidosis Type I, Sarah Hurt
Dissecting the role of chromatin remodeling in direct lineage reprogramming, Kunal Jindal
The Role of Group 2 Innate Lymphoid Cells in Restoring Lung Health and Chitinase Function After Epithelial Injury, Haerin Jung
Stromal Reprogramming by FAK Inhibition Overcomes Radiation Resistance to Allow for Immune Priming and Response to Checkpoint Blockade, Varintra Lander
Mechanisms of Rod Photoreceptor Metabolism and Function in Health and Disease, Tae Jun Lee
Germinal Center Persistence Diversifies B Cell Responses to Vaccination, Katherine Marie McIntire
Regulation of neuronal cell-type-specific transcription by non-CG methylation and MeCP2, James Russell Moore
Understanding Gene Regulation by Non-CG DNA Methylation and MeCP2 at Cellular Resolution in the Brain, Mati Nemera
Determining the Role of DDR2 in Acquired Chemo-Resistance in Ovarian Cancer, Alyssa Oplt
Dual Modes of Dopamine Underly Distinct Facets of Impulsive Actions, Tzvia Pinkhasov
Inferring Function from Form: Subcortical Projection Cell Types in Rat Orbitofrontal Cortex, Suelynn Ren
The Macrophage Autophagy-Lysosome System in Atherosclerosis Pathogenesis, Astrid Carolina Rodriguez Velez
Novel Strategies to Target Uropathogenic Escherichia coli in the Bladder and Gut, Jesus Miguel Santiago Borges
Investigating Tumor-Stroma Interactions During Ovarian Cancer Metastasis, Angela Marie Schab
Aging Drives CD8 T Cells to Functional Extremes: From Non-Specific Cytotoxicity to Tissue-Mediated Exhaustion, Irina Shchukina
Insulin-like Growth Factor Regulation of Nutrition-Dependent Growth, Regeneration, and Tumorigenesis, Jonathan Lamouth Spalding
Antimicrobial Mechanisms of Human Lipocalin-2, Lindsey Steinberg
Investigating the Involvement of GABAergic Interneurons and a Gene Therapy Strategy for Epilepsy in CLN2 Disease, Keigo Takahashi
The structural biology of gamma-4 CUP pili, Kevin Omeed Tamadonfar
Elucidating the Heterogeneity and Epigenetic Determinants of Memory-like Natural Killer Cell Differentiation, Jennifer Tran
Rapid Unleashing Macrophage Efferocytic Capacity by Transcriptional Pause Release, Turan Tufan
Microbial Community Composition and Assembly in Diverse Environmental Systems, Rhiannon Celeste Vargas
Novel bioinformatics tools for biomarker discovery in prostate cancer, Jace Webster
Identification and Characterization of UBE3A Gain of Function Variants as a Driver of Neurodevelopmental Disease, Kellan Phoebe Weston
Integrating DNA Methylation and 3D-genome Architecture to Identify Functional Regulatory Sequences in IDH-mutant AML, Elisabeth Wilson
Functions of cDC1 in Mediating CD4+ Help for CD8+ T cells, Renee Wu
Neuroepigenetic Mechanisms of Brain Development: From Technology to Biological Insights, Allen Yen
Lineage tracing of twins and families using massively parallel sequencing, Christopher Jongsoo Yoon
Mechanisms of Electrical Substrate Reprogramming after Cardiac Radiotherapy, David Meng Zhang
Investigating the Role of Circular RNAs in Metastatic Colorectal Cancer Progression, Sidi Zhao
Theses/Dissertations from 2023
Investigation of Metabolic and Molecular Pathways that Promote Gastric Parietal Cell Regeneration, Mahliyah Lenore Adkins-Threats
Combining Simulations and Single Molecule Spectroscopy To Understand SARS-CoV-2 Nucleocapsid Protein-RNA Interactions, Jhullian Jamille Alston
Modeling X-Linked Dystonia Parkinsonism (XDP) in Patient-Derived Medium Spiny Neurons, Shivani Aryal
Bioinformatic tools to alleviate the annotation bottleneck within precision oncology, Erica Kay Barnell
A Thesis on Phosphatidylserine as a Key Signaling Moiety During Adipocyte Differentiation, Brady Jeffrey Barron
Maternal-Fetal Circadian Communication during Pregnancy, Keenan Bates
Understanding the Spectrum of DNMT3A Mutations in Neurodevelopmental Disease, Diana Christian Beard
Mechanisms and Consequences of Microtubule-Based Symmetry Breaking in Plant Roots, Natasha Anriel Bilkey
Investigating the role of DciA during the cell cycle in Mycobacterium, Helen Catherine Blaine
Antibiotic Resistance at Sequence, Population, and Global Scales, Kevin Blake
Roles of Type I Interferon Signaling in Drug Resistant Mycobacterium tuberculosis Infection, Suhas Bobba
Wide-field optical imaging of neurological disorders and sleep in mice, Lindsey M. Brier
Multi-Scalar Contributions to Sex Differences in Brain Tumor Incidence and Outcome, Lauren Broestl
Inhibiting Notch Signaling in miNs Improves Neurite Extension & Investigating the Epigenome of Alzheimer’s Disease, Kyle Foster Burbach
Dissecting Tau Isoform Control and Modeling Tauopathies in Directly-Reprogrammed Neurons, Lucia Capano
Identifying the Molecular Fate Logic Underlying Direct Neuronal Conversion, Kitra Cates
UvrD1 Helicase of Mycobacterium tuberculosis that can be Activated by Multiple Unique Mechanisms, Ankita Chadda
Investigating the relationship between smoking, genomics, and brain imaging, Yoonhoo Chang
Investigation of the Deubiquitinating Enzyme USP7 in the Brain, Hao Chen
The role of the neurodevelopmental disorder gene Myt1l in mammalian brain development, Jiayang Chen
The role of the neurodevelopmental disorder gene Myt1l in mammalian brain development, Jiayang Chen
Assessment of Cross-protective Responses to Emerging Variant Viruses, Rita Elaine Chen
An Evolving View of Host-Microbiome Co-Development in Healthy and Undernourished Children, Robert Yuzen Chen
Restoring the Mechanoresponsiveness of Aged Bone to Mechanical Loading, Christopher John Chermside-Scabbo
Investigating how sterol transport affects survival of the pathogenic fungus Cryptococcus neoformans in host-like conditions, Hau Lam Choy
IL-15 and IFN-g regulation in murine NK cells, Maria Cimpean
On the Origin of AIDS: CARD8’s Role in Pathogenesis and Cure, Kolin Clark
ZFP36 Family-Mediated Post-Transcriptional and Bhlhe40-Mediated Transcriptional Regulation of T Cell Responses, Melissa Erin Cook
Leveraging protein dynamics to drug filovirus protein-nucleic acid interactions using simulations and experiments, Matthew Alberto Cruz
Leveraging protein dynamics to drug filovirus protein-nucleic acid interactions using simulations and experiments, Matthew Alberto Cruz
Single-molecule Spectroscopy of the SARS-CoV-2 Nucleocapsid Protein, Jasmine Cubuk
Cardiovascular SARS-CoV-2 Tropism and Immunopathology, Oleksandr Dmytrenko
A Quantum Physics-Based Force Field for Biomolecular Simulation, Roseane dos Reis Silva
The Evolution of Transposable Elements as Cis-Regulatory Elements in Mammals, Alan Y. Du
Genetic and Pharmacological Factors Control Aging in Caenorhabditis elegans., Brian McNally Egan
Investigating Cassava Susceptibility to Xanthomonas Induced Bacterial Blight Using Disease Phenotyping and Genome Engineering Strategies, Kiona Rajene Elliott
Distinct Roles for LTα3 and LTα1β2 Produced by B cells Contribute to their Multi-Faceted Impact on Ileitis, Emma Claire Erlich
Wild Plant–Pathogen Interactions Across Gradients of Urbanization and Latitude, Quinn N. Fox
Iterative Machine Learning of a Cis-Regulatory Grammar, Ryan Z. Friedman
Understanding the Chemical Context of Interactions in Intrinsically Disordered Proteins, Garrett Ginell
TRPM5's Role in Vascular Development, Megan Goeckel
Role of Copyback Viral Genomes in Activating Cellular Stress Responses During Pneumovirus and Paramyxovirus Infection, Lavinia Jose Gonzalez Aparicio
Circumventing Drug Resistance with Small Molecule Inhibitors of Mycobacterium tuberculosis, Gregory Alexander Harrison
A Dynamic Duo: Investigating the Interactions between Xanthomonas citri pv. malvacearum and Pseudomonas syringae, Taylor Harris
Function and Regulation of Virulence-Associated Siderophores in Uropathogenic Enterobacterales, James Robert Heffernan
Function and Regulation of Virulence-Associated Siderophores in Uropathogenic Enterobacterales, James Robert Heffernan
Biotic Interactions and the Maintenance of Biodiversity across a Tropical Elevational Gradient, David Henderson
Investigating the Role of BHLHE40 in Host Responses to Mycobacterium tuberculosis Infection and Myeloid Cell Development, Skyler Hendrix
The Role of Phenylacetic Acid (PAA) Catabolism in Acinetobacter Physiology, Anna Josephine Hooppaw
Individual and Social Influences on Cigarette Smoking During Pregnancy, Alexandra Noel Houston-Ludlam
DFCP1 Regulates Lipid Droplet Catabolism in an NTPase-Dependent Manner, Victoria Anne Ismail
Heterogeneity of Human Tissue-Resident Lymphocytes, Natalia Jaeger
Fluorescent-based Approaches for Quantifying Bacterial Transcription Initiation Kinetics, Drake Jensen