Theses/Dissertations from 2024
Cellular and Molecular Basis of CD4+ T Cell Help at the Effector Phase During Immunotherapy of MHC-II Negative Tumors, Samuel Oche Ameh
Aging Antiviral Immunity In The Central Nervous System: Mechanisms And Implications, Artem D. Arutyunov
Mechanisms of uropathogenic E. coli reservoir formation in the gastrointestinal tract, Philippe Nimma Azimzadeh
Interleukin-1α and Leukemia Inhibitory Factor Promote Cancer-Induced Extramedullary Hematopoiesis, Derek Arthur George Barisas
Inducible CRISPR-Targeted ‘Knockdown’ of Human Gut Bacteroides in Mice Reveals Glycan Utilization Strategies, Zachary Beller
Development and Structure of Spinal Interneuron Connectivity in Larval Zebrafish, Saul Bello Rojas
Employing Single-Nucleus RNA-Seq to Uncover Genetic Factors of Alzheimer Disease, Logan Brase
Predicting Cell Fate Using Single-Cell State and Lineage Information, Emily Grace Butka
Gnotobiotic Mouse Models For Characterizing the Role of the Microbiota On Undernutrition and Early Postnatal Brain Development, Alexandra Elizabeth Byrne
Developing tools to study the effect of the mechanical environment on plant cell growth and morphogenesis, Ryan Calcutt
Epigenetic Dynamics in Zebrafish Development and Regeneration, Yujie Chen
Discovery and Functional Characterization of Proteins Encoded by Annotated Long Noncoding Ribonucleic Acids, Emily Coonrod
Evaluating Pathological Tau Spread in Early Alzheimer Disease: Developing a Metric for Tau Positron Emission Tomography Quantifying Tau Spatial Spread, Stephanie Sierra Doering
Characterizing the Causal Role of SVEP1 in Human Disease, Jared S. Elenbaas
Dimerization of the Fluoride Channel Fluc in Membranes, Melanie Ernst
Tracking and Mitigating Imprint Erasure During Human Pluripotent State Transitions, Laura A. Fischer
Applications of Bioinformatics for Exploring the Genomic Landscape of Cancer and Characterizing Treatment Response for Precision Oncology, Sharon Freshour
The Cell Biology of Cryptococcal Capsule Production, Elizabeth Gaylord
Leveraging Microbes to Improve Cancer Outcomes, Olivia Nicole Gorushi
Developing Computational and Experimental Tools for Investigating Intrinsically Disordered Proteins and Biomolecular Condensates, Daniel Griffith
The clinical significance and genetic origin of p14ARF, Anna Louise Grobelny Guthrie
A Test of the Pioneer Factor Hypothesis for Silent Gene Activation, Jeffrey Hansen
Vascular Electrophysiology and Pathogenic Consequences of Cardiovascular KATP Channel Mutations, Alex Hanson
A Dynamic Duo: Investigating the Interactions between Xanthomonas citri pv. malvacearum and Pseudomonas syringae, Taylor Harris
Treatment Modifications and Development for Mucopolysaccharidosis Type I, Sarah Hurt
Dissecting the role of chromatin remodeling in direct lineage reprogramming, Kunal Jindal
The Role of Group 2 Innate Lymphoid Cells in Restoring Lung Health and Chitinase Function After Epithelial Injury, Haerin Jung
Effects of Hypoxia on Monocyte Differentiation and Macrophage Specification during Ischemic Heart Injury, Farid Faridovich Kadyrov
Molecular Mechanisms Behind Methionine-Derived Glucosinolate Diversity in Brassica Plants, Vivian Kitainda
Stromal Reprogramming by FAK Inhibition Overcomes Radiation Resistance to Allow for Immune Priming and Response to Checkpoint Blockade, Varintra Lander
Mechanisms of Rod Photoreceptor Metabolism and Function in Health and Disease, Tae Jun Lee
Germline Genetic Determinates of Cancer and Pre-Malignant Conditions, Jie Liu
Island Hopping in the Tropics: Conservation Genetics, Speciation, and Biogeography in the Iconic Flowering Plant Group Hibiscus sect. Lilibiscus, Brock Mashburn
An Intronic Regulatory Element Limits Tcf7 Expression in Natural Killer Cells, Matthew Vincent McCullen
Germinal Center Persistence Diversifies B Cell Responses to Vaccination, Katherine Marie McIntire
Regulation of neuronal cell-type-specific transcription by non-CG methylation and MeCP2, James Russell Moore
Insights from open conformations of EcMscK, hTRPV4, and hHCN1 into the structural basis of ligand-regulated ion channel gating, Jonathan Mount
Understanding Gene Regulation by Non-CG DNA Methylation and MeCP2 at Cellular Resolution in the Brain, Mati Nemera
Determining the Role of DDR2 in Acquired Chemo-Resistance in Ovarian Cancer, Alyssa Oplt
Investigation of PHOTOPERIODIC CONTROL OF HYPOCOTYL 1’s Role in Promoting Phytochrome B-Photobody Phase Separation, Sarah Anne Pardi
Dual Modes of Dopamine Underly Distinct Facets of Impulsive Actions, Tzvia Pinkhasov
Understanding the Relationship between Genetic and Epigenetic Variation at a Species and Individual Level, Kara Quaid
Inferring Function from Form: Subcortical Projection Cell Types in Rat Orbitofrontal Cortex, Suelynn Ren
The Macrophage Autophagy-Lysosome System in Atherosclerosis Pathogenesis, Astrid Carolina Rodriguez Velez
Novel Strategies to Target Uropathogenic Escherichia coli in the Bladder and Gut, Jesus Miguel Santiago Borges
Investigating Tumor-Stroma Interactions During Ovarian Cancer Metastasis, Angela Marie Schab
Aging Drives CD8 T Cells to Functional Extremes: From Non-Specific Cytotoxicity to Tissue-Mediated Exhaustion, Irina Shchukina
Insulin-like Growth Factor Regulation of Nutrition-Dependent Growth, Regeneration, and Tumorigenesis, Jonathan Lamouth Spalding
Systemic Activation of the Axon Degeneration Executioner SARM1 Triggers Acute Hyperglycemia, Lillian Spatz
Antimicrobial Mechanisms of Human Lipocalin-2, Lindsey Steinberg
Investigating the Involvement of GABAergic Interneurons and a Gene Therapy Strategy for Epilepsy in CLN2 Disease, Keigo Takahashi
The structural biology of gamma-4 CUP pili, Kevin Omeed Tamadonfar
Elucidating the Heterogeneity and Epigenetic Determinants of Memory-like Natural Killer Cell Differentiation, Jennifer Tran
Rapid Unleashing Macrophage Efferocytic Capacity by Transcriptional Pause Release, Turan Tufan
Microbial Community Composition and Assembly in Diverse Environmental Systems, Rhiannon Celeste Vargas
Novel bioinformatics tools for biomarker discovery in prostate cancer, Jace Webster
Identification and Characterization of UBE3A Gain of Function Variants as a Driver of Neurodevelopmental Disease, Kellan Phoebe Weston
Integrating DNA Methylation and 3D-genome Architecture to Identify Functional Regulatory Sequences in IDH-mutant AML, Elisabeth Wilson
Functions of cDC1 in Mediating CD4+ Help for CD8+ T cells, Renee Wu
Sleep Restores an Optimal Computational Regime in Cortical Networks, Yifan Xu
Neuroepigenetic Mechanisms of Brain Development: From Technology to Biological Insights, Allen Yen
Lineage tracing of twins and families using massively parallel sequencing, Christopher Jongsoo Yoon
Mechanisms of Electrical Substrate Reprogramming after Cardiac Radiotherapy, David Meng Zhang
Investigating the Role of Circular RNAs in Metastatic Colorectal Cancer Progression, Sidi Zhao
Transcriptional precision in photoreceptor development and diseases - Lessons from the retinal transcription factor CRX, Yiqiao Zheng
Theses/Dissertations from 2023
Investigation of Metabolic and Molecular Pathways that Promote Gastric Parietal Cell Regeneration, Mahliyah Lenore Adkins-Threats
Combining Simulations and Single Molecule Spectroscopy To Understand SARS-CoV-2 Nucleocapsid Protein-RNA Interactions, Jhullian Jamille Alston
Modeling X-Linked Dystonia Parkinsonism (XDP) in Patient-Derived Medium Spiny Neurons, Shivani Aryal
Bioinformatic tools to alleviate the annotation bottleneck within precision oncology, Erica Kay Barnell
A Thesis on Phosphatidylserine as a Key Signaling Moiety During Adipocyte Differentiation, Brady Jeffrey Barron
Maternal-Fetal Circadian Communication during Pregnancy, Keenan Bates
Understanding the Spectrum of DNMT3A Mutations in Neurodevelopmental Disease, Diana Christian Beard
Mechanisms and Consequences of Microtubule-Based Symmetry Breaking in Plant Roots, Natasha Anriel Bilkey
Investigating the role of DciA during the cell cycle in Mycobacterium, Helen Catherine Blaine
Antibiotic Resistance at Sequence, Population, and Global Scales, Kevin Blake
Roles of Type I Interferon Signaling in Drug Resistant Mycobacterium tuberculosis Infection, Suhas Bobba
Wide-field optical imaging of neurological disorders and sleep in mice, Lindsey M. Brier
Multi-Scalar Contributions to Sex Differences in Brain Tumor Incidence and Outcome, Lauren Broestl
Inhibiting Notch Signaling in miNs Improves Neurite Extension & Investigating the Epigenome of Alzheimer’s Disease, Kyle Foster Burbach
Dissecting Tau Isoform Control and Modeling Tauopathies in Directly-Reprogrammed Neurons, Lucia Capano
Identifying the Molecular Fate Logic Underlying Direct Neuronal Conversion, Kitra Cates
UvrD1 Helicase of Mycobacterium tuberculosis that can be Activated by Multiple Unique Mechanisms, Ankita Chadda
Investigating the relationship between smoking, genomics, and brain imaging, Yoonhoo Chang
Investigation of the Deubiquitinating Enzyme USP7 in the Brain, Hao Chen
The role of the neurodevelopmental disorder gene Myt1l in mammalian brain development, Jiayang Chen
The role of the neurodevelopmental disorder gene Myt1l in mammalian brain development, Jiayang Chen
Assessment of Cross-protective Responses to Emerging Variant Viruses, Rita Elaine Chen
An Evolving View of Host-Microbiome Co-Development in Healthy and Undernourished Children, Robert Yuzen Chen
Restoring the Mechanoresponsiveness of Aged Bone to Mechanical Loading, Christopher John Chermside-Scabbo
Investigating how sterol transport affects survival of the pathogenic fungus Cryptococcus neoformans in host-like conditions, Hau Lam Choy
IL-15 and IFN-g regulation in murine NK cells, Maria Cimpean
On the Origin of AIDS: CARD8’s Role in Pathogenesis and Cure, Kolin Clark
ZFP36 Family-Mediated Post-Transcriptional and Bhlhe40-Mediated Transcriptional Regulation of T Cell Responses, Melissa Erin Cook