Theses/Dissertations from 2021
Role of 4R tau in astrocyte-mediated neuronal toxicity and the progression of neurodegenerative disease, Lubov Alexandra Ezerskiy
Testing Janzen’s Physiological Barrier Hypothesis Through Experimental Evolution and Biogeographic Studies on Sister Species Pairs, Vincent John Fasanello
Regulatory Effects of the E. coli RecBCD Nuclease Domain on DNA Unwinding Kinetics, Nicole Fazio
SLO2.1 channels: a new molecular mechanism to regulate uterine excitability, Juan Jose Ferreira
Computational Approaches for Screening Drugs for Bioactivation, Reactive Metabolite Formation, and Toxicity, Noah Flynn
Identifying Subpopulation-level Methylation Patterns in Hematological Malignancies, Jerry Fong
The Regulation of Plasmodium falciparum Metabolism by Haloacid Dehalogenase Proteins, Philip Frasse
Sex Differences in the Role of Cornichon Homolog-3 on Spatial Memory and Synaptic Plasticity, Hannah Elizabeth Frye
Analysis of Structural Variation and mtDNA Copy Number in Finns, Liron Ganel
The Genetic Basis of Adaptation to Environmental Stress in Two Grass Genomic Model Systems, David Mitchell Goad
Regulation of genome architecture by chromatin remodeling in the brain, Jared Vega Goodman
The Role of CD53 in Hematopoietic Development, Stress, and Malignancy, Zev Joshua Greenberg
Single-Cell Resolution Mechanistic Analyses of Direct Lineage Reprogramming, Chuner Guo
Understanding the Molecular Mechanisms of Photoferrotrophy and Phototrophic Extracellular Electron Uptake, Dinesh Gupta
Thermodynamics and Conformational Heterogeneity of RecBCD Binding to DNA Ends, Linxuan Hao
Linking Neuronal Protein Phosphatase 2A to the DLK Stress Kinase Signaling Cascade, Margaret Hayne
Dendritic Processing and Efficient Coding in the Retina, Jen-Chun Hsiang
The Roles of Capsular Polysaccharides and Diet in the Immune Response to a Bacteroides thetaiotaomicron Antigen, Samantha Hsieh
Dissecting the Role and Regulation of Transcription Factor Zeb2 in Hematopoiesis, Xiao Huang
The immunoregulation of autoimmune diabetes, Hao Hu
Retinal Ganglion Cells Underlying Visual Perception and Predation in Mice, Keith Patrick Johnson
Method Development for Enhancing Sensitivity of Dynamic Nuclear Polarization Nuclear Magnetic Resonance Spectroscopy for Structural Studies of PKC-Drug Interactions, Patrick Terrence Judge
Etv2/Myct1 axis in the regulation of tumor angiogenesis and anti-tumor immunity, Ashraf Ul Kabir
Cancer Epigenome Reprogramming, Jennifer Ann Karlow
Copper-mediated Regulation of a Traditional Iron Uptake System in Uropathogenic Escherichia coli., George Lwanga Katumba
Quantitative Characterization of Microbial Ecologies in Dysbiosis and Infection, Eric Keen
The Role of Excited States in Determining β-lactamase Function and Bacterial Fitness, Catherine Rae Knoverek
Influence of Aging and Cerebrovascular Disease on Neuroimaging Measures of Alzheimer Disease, Lauren Nicole Koenig
Gut Reactions: Quantitative Predictions of the Responses of Human Gut Microbiota to Medical Interventions, Amy Elizabeth Langdon
Stem Cell Models to Study the Regulation of Human Cortical Development and Its Disruption in Neurodevelopmental Disorders, Emily Megan Alexandra Lewis
Identify Genetic and Epigenetic Abnormalities Associated with Therapeutic Vulnerability in Human Cancers, Wen-Wei Liang
Regulation of transcription factor binding specificity: from binding motifs to local DNA context, Jiayue Liu
Vestibulospinal circuit in the larval zebrafish, Zhikai Liu
Type I Interferon Regulation of Chikungunya Virus Pathogenesis, Marissa Christine Locke
Regulation, Architecture, and Function of the Type VI Secretion System of Acinetobacter baumannii, Juvenal Lopez
The Phylogeography of Rare Central Tennessee Glade Endemics Trifolium calcaricum and Viola egglestonii, Rachel Ann Lyman
Genetic Effects Mediated Through Epistatic Networks Onto Metabolic Traits, Juan Francisco Macias-Velasco
Transcriptional and Epigenetic Regulation of Cerebellar Development and Function, Shahriyar Majidi
Dissecting the neural circuits mediating pain-induced negative affect and drug-seeking behaviors, Tamara Markovic
Deep Learning Deleterious Small Molecule Biochemistry from the Lab to the Clinic, Matthew Matlock
Investigation of IFNγ-induced Control of Intracellular Pathogens, Michael Mcallaster
Ascension and Adhesion of Uropathogenic Escherichia coli during Pyelonephritis, Lisa Kristine McLellan
Modularity of Feedback for State-Dependent Guidance of Navigation in Mouse Visual Cortex, Andrew M. Meier
Developments in Proteomics, Trans-Splicing Technology And Endogenous Transcript Manipulation, Justin Alexander Melendez
The Role of Subclonal Gene Mutations During Progression from Myelodysplastic Syndrome to Secondary Acute Myeloid Leukemia, Andrew John Menssen
A Novel Function of Plasmacytoid Dendritic Cells in Regulating Type 2 Immune Responses, Hannah Leigh Miller
Prodrug Activation in Staphylococci and the Implications for Antimicrobial Development, Justin J. Miller
Exploring β-cell Function and Heterogeneity in Obese SM/J Mice, Mario Alejandro Miranda
Deconvolving Genomic Regulatory Heterogeneity with Self-Reporting Transposons, Arnav Moudgil
The roles of plasmepsins IX and X in malaria parasite biology, Armiyaw Sebastian Nasamu
The evolving mammalian 3D epigenome, Mayank Choudhary Nishikant Choudhary
Metabolic Control and Immune Barriers of Hematopoietic Stem Cells, Hannah Pizzato
Regulation of Host-Microbe Interactions in Autoimmunity and Antiviral Immunity by Cytosolic Nucleic Acid Sensing and Interferon Signaling, Derek Jerome Platt
On the challenges and rewards of analyzing molecular dynamics at the terabyte and millisecond scale, Justin Roy Porter
RNA Polymerase Binding Protein A (RbpA) Regulation of Mycobacteria Transcription and Sensitivity to Fidaxomicin, Jerome Prusa
Genetic Variations in the Regulation and Biosynthesis of Polycyclic Tetramate Macrolactams, Yunci Qi
The Role of Mature Secretory Cells in Gastrointestinal Regeneration, Megan Deanna Radyk
Functional Optical Imaging of the Developing Mouse Cortex in Health and Disease, Rachel Marlene Rahn
Comprehensive Characterization of the Genetic and Neoantigen Landscapes of Follicular Lymphoma Patients Supports the Feasibility of Personalized Cancer Vaccine Treatments, Cody Alexander Ramirez
Targeting the PHGDH-mTOR Metabolic Axis in Osteosarcoma, Richa Rathore
Exploring the intrinsic and extrinsic factors that regulate breast cancer cell dormancy, Qihao Ren
The Origins & Functional Effects of Postzygotic Mutations Throughout the Human Lifespan, Nicole Briana Rockweiler
Discovery of Sex Differences in Response to p53 Loss and Gain-of-Function in Glioblastoma, Nathan Cuyle Rockwell
Role of Secretory Leukocyte Protease Inhibitor in Urinary Tract Infection, Anne Rosen
Influence of Focal Activity on Macroscale Brain Dynamics in Health and Disease, Zachary Pollack Rosenthal
Investigating the Role of Bladder Epithelial Stem Cells in Bladder Mucosal Remodeling and Defense Against Infection, Seongmi Kim Russell
Regulation of Gut Commensal-Specific T Cell Differentiation by Dendritic Cell Subsets, Emilie Russler-Germain
Measuring and Manipulating Tension-Dependent Behavior of Mechanosensitive Ion Channels, Angela M. Schlegel
Structural Variants Are a Major Source of Gene Expression Differences in Humans and Often Affect Multiple Nearby Genes, Alexandra Jane Scott
Precision Diffusion Imaging to Analyze Individual-Specific Plasticity, Nicole Andrea Seider
Relating Spontaneous Activity and Cognitive States via NeuroDynamic Modeling, Matthew Singh
Understanding and Exploiting Protein Allostery and Dynamics Using Molecular Simulations, Sukrit Singh
Regulation of Metabolic Stress by the Snhg3 Locus, Arthur Curtis Sletten
Characterizing a Novel Metabolic Pathogenic Mechanism in Familial Hemiplegic Migraine, Sarah Elizabeth Smith
Glial inflammatory responses regulate neurocognitive recovery following viral encephalitis, Allison Luen Soung
Role of Interferon Receptors in STING-Associated Autoinflammatory Disease in Mice, William Alexander Stinson
Structural Analysis and Vaccine Efficacy of Hla mutants, Kelly Tomaszewski
Uncovering a MYC-driven Tumor-suppressive Program in Proliferating Lymphocytes, Elena Tonc
Investigating the differentiation and functional maturation of stem cell-derived β cells, Leonardo Velazco-Cruz
Mechanisms of Natural Killer Cell Anti-Tumor Function and Homeostasis, Julia Alexandra Wagner
Peripheral Nerve Macrophages and Their Implications in Neuroimmunity, Peter Leon Wang
Regional Reprogramming and the Small Intestine: Analysis and Modeling of Adaptive Regeneration of the Epithelium, Sarah Elizabeth Waye
Weedy rice as a model system for the study of microevolutionary interactions in agricultural contexts, Marshall Jon Wedger
Genetic risk factors for neurodevelopmental disorders: insights from hiPSC-cerebral organoids, Michelle L. Wegscheid
Of Mice and Toddlers: A Cross-Species Investigation of the Social Motivation Theory of Autism, Claire Weichselbaum
Causal Function and Bias Correlation of the Orbitofrontal Cortex in Economic Choices, Shi Weikang
Computational Analysis of Non-CpG DNA Methylation in the Mammalian Nervous System, Dennis Yawen Wu
Apolipoprotein E Immunotherapy for the Preclinical Treatment of Alzheimer Disease and Cerebral Amyloid Angiopathy, Monica Xiong
The Role of Neuronal ATP-sensitive Potassium Channels in Learning and Memory, Shaul Vladimir Yahil
Contribution of TGF-b Signaling to the Pathogenesis of Myeloproliferative Neoplasms, Juo-Chin Yao
Disentangling Glial Diversity in Peripheral Nerves at Single Nuclei Resolution, Aldrin Kay Yuen Yim
The Role of eNAMPT-mediated Systemic NAD+ Biosynthesis in Aging and Lifespan, Mitsukuni Yoshida
Theses/Dissertations from 2020
Genetic Interactions and Maternal Genes Modulate Congenital Heart Disease Risk, Ehiole Ogboma Akhirome
Lymphatic Filariasis: Host and Parasite Factors and the Pathogenesis of Systemic Adverse Events Following Treatment, Britt Juul Andersen
Structural insights into host-pathogen interactions of alphaviruses, Katherine Basore
Mechanisms of STING-Associated Vasculopathy and Immunodeficiency, Brock Gordon Bennion