Theses/Dissertations from 2023
Shining a Light through a Multiomic Lens on Germline Variants: Patterns and Functional Implications Across Cancer Types, Fernanda Martins Rodrigues
Function of Deubiquitinase MYSM1 in Attenuation of DNA Damage Responses, Brendan Mathias
Understanding Thermotolerance in Photosynthetic Cells: From Green Algae to Land Plants, Erin Marie Mattoon
tRNA Methyltransferases Mediate Acinetobacter baumannii Pathobiology, Jenna McGuffey
Circadian Protein BMAL1 Regulates Astrocyte Activation and Protein Degradation in Health and Disease, Celia Augusta Mckee
Evaluating the Utility of S100A8/A9 as a Non-Invasive Biomarker, Leah Mellett
Mass Spectrometry-Based Discovery of Tumor Antigens for Cancer Immunotherapy, Wei Meng
The role of Gardnerella in bacterial vaginosis and facilitating colonization by Neisseria gonorrhoeae, Sydney Rose Morrill
Development of Myelin in Wolfram Syndrome, Olga Reine Neyman
The Painful Problem: Improving Preclinical Pain Assessment to Probe Locus Coeruleus Noradrenergic Adaptations During Chronic Pain, Makenzie Norris
Roles of the Transcription Factors Bcl6, IRF2, and Notch2 in Myeloid Development, Kevin William O'connor
Dynamics of Epithelial Differentiation Following Intestinal Villus Injury, Takahiro Erick Ohara
Following the Paper Trail: An Ethnoecology of Hand Papermaking Traditions, James Ojascastro
Effect of Age at Injury on Neuroinflammatory Response, Microstructural Outcomes, and Function Following Traumatic Brain Injury, Sydney J. Oswalt Reitz
The Regulation of Innate Lymphoid Cells, Vincent Peng
An Investigation of Second-Site Non-Complementation among Motile Cilia Genes in Chlamydomonas reinhardtii, Gervette M. Penny
An Investigation of Second-Site Non-Complementation among Motile Cilia Genes in Chlamydomonas reinhardtii, Gervette M. Penny
Examining the Role of Microglia in Diabetic Retinopathy: Phenotypes, Mechanisms, and Therapies, Charles W. Pfeifer
Characterizing the Significance of polyA tracks in Gene Regulation and Disease, Geralle Norlene Powell-Rodgers
Sources and consequences of cell-to-cell variability in gene expression, Avinash Ramu
Unraveling the Molecular Basis of Zinc Cluster Transcription Factor Specificity: A Comprehensive Study of Half-Site Promoter Binding Interactions and their Role in Gene Expression Regulation, Pamela Samantha Recio
Investigating Novel Neoantigen Sources for Personalized Cancer Vaccines, Megan Richters
Identifying Molecular Targets of ADAR1 Dependency in Breast Cancer, Sua Ryu
Influence of Environmental Gradients on Genomic Variation in Pediatric Commensals and Pathogens, Sanjam Sawhney
Cancer Immunogenomics Approaches to Characterizing and Treating Malignant Brain Tumors, Maximilian Oswald Schaettler
Context Dependence, Cheating, and Long-term Conflict in Social Interactions, Trey Scott
Development of computational and experimental approaches for RNA virus serology, Brittany Kaye Smith
Automated Processing of Metabolomics Data for Population-scale Studies, Ethan Stancliffe
Apolipoprotein E Adopts an Antiparallel Dimer in Discoidal Lipoproteins, Michael Ray Strickland
A Human STAT3 GOF Variant Alters T Cell Function to Drive Skin Inflammation, Kelsey Adele Toth
Mapping Brain Development and Decoding Brain Activity with Diffuse Optical Tomography, Kalyan Tripathy
A Thesis on the Human Genetic Basis of Severe Pneumococcal Infection in Papua New Guinea, Emma Catherine Walker
Charting the Landscape of Ventral Stream Neural Code on Generative Image Manifolds, Binxu Wang
The Role of NS1 in Flavivirus Immunity and Pathogenesis, Alex W. Wessel
The influence of the gut microbiota on asthma in school-aged children and adults, Naomi Grace Wilson
Immunity to Emerging RNA Viruses, Emma Winkler
T-bet and Eomes Are Required for Mature NK Cell Homeostasis and Function, Pamela Wong
Improving Neoantigen Prioritization Methods for Personalized Cancer Vaccines, Huiming Xia
TFEB degradation is regulated by an IKK/β-TrCP2 phosphorylation-ubiquitination cascade, Yan Xiong
Physiological Heterogeneity and Pain-Associated Plasticity in Human Sensory Neurons, Jiwon Yi
Structural Basis of Gating in MSL Channels, Jingying Zhang
Mechanisms of transcription regulation by CarD in Mycobacterium, Dennis Xiaoqian Zhu
Theses/Dissertations from 2022
The Effects of NMDA Antagonism on Neuronal Activity and Neurovascular Coupling in Non-Human Primate Cortex, Benjamin Thomas Acland
System shock: Using -omics data to characterize biological remodeling in the microbiome, resistome, and transcriptome of bacteria, Winston Eugene Anthony
Antigen Presentation in Central Nervous System Antitumor Immunity, Jay Aaron Bowman-Kirigin
Characterizing complex affective processing across age and in relation to social anxiety symptoms, M. Catalina Camacho
The role of the neurodevelopmental disorder gene Myt1l in mammalian brain development, Jiayang Chen
Connections between Mechanosensitive Ion Channel MSL10 and ER-Plasma Membrane Contact Sites, Jennette Marie Codjoe
Bioinformatics and cancer genomics approaches to advance precision medicine and elucidate tumor mutational landscapes, Kelsy Cotto
Circadian Circuitry and Glioblastoma: Interactions with Behavior, Carcinogenesis, and Clinical Practice., Anna R. Damato
Control of Intestinal Turnover and Cell Death through Canonical Autophagy Pathways within Mouse and Human Epithelia, John Steven Ekman
A structural perspective on neutralizing antibodies to flaviviruses and coronaviruses, John Michael Errico
Fructose Promotes the Growth of Tumors through Metabolite Exchange with Non-malignant Tissues, Ronald Joseph Fowle-Grider
Regulation and Function of Integrin β3 in Bone-Metastatic Breast Cancer Cells in the Therapeutic Setting, Gregory Chandler Fox
Functional Analysis of Recurrent Non-Coding Variants in Human Melanoma, Paula Maria Godoy
Functional and anatomical characterization of descending periaqueductal gray (PAG) projections and their role in pain modulation, Jose Gabriel Grajales
The Enemy Within: An Investigation of the Intracellular Bacteria in Urinary Tract Infections, Jennie Elizabeth Hazen
The role of Fibroblast Growth Factor-9 in influenza A virus pathogenesis, Bradley Edward Hiller
Uncovering New Mechanisms for Indole-3-butyric Acid Metabolism and Transport in Arabidopsis thaliana, Arielle Lynne Homayouni
Understanding gene regulation with high-throughput genome-integrated reporter assays, Clarice Hong
Understanding Individual Cells in Zebrafish Caudal Fin Regeneration (从单细胞视角理解斑马鱼尾鳍再生历程), Yiran Hou
Analyzing the Interconnectedness of the Human Genome, Nicholas Jacobs
Assembly and Repair of Photosystem II, Virginia M. Johnson
Determinants of DNA Damage Responses During B Cell Development, Rachel Leigh Johnston
Host development and microbiota influences on norovirus infection, Elizabeth Alexandra Kennedy
DNMT3A Regulates Hematopoietic Stem Cells via DNA Methylation-Independent Functions, Won Kyun Koh
Unraveling Population Heterogeneity using Single-Cell Analysis, Wenjun Kong
The Impact of Nucleolar Stress on Thymocyte Development and T Cell Acute Lymphoblastic Leukemia Transformation, Joseph Ryan Krambs
The Role of SOXE Transcription Factors in Melanoma Initiation, Eva Tulchinsky Kramer
Contributions of Specific Retinal Circuits and Their Respective Projections to Visual Behaviors, Jenna Mackenzie Krizan
Massively Parallel Assessment of the Functional Effects of De Novo Autism Spectrum Disorder Patient-Derived Genetic Variants in 3’ Untranslated Regions, Tomas Lagunas Jr
Techniques for Spatial Analysis of C. elegans Anatomy and Reporter Expression, Nicolette Marie Laird
Inferring adaptation in social microbes from experimental evolution under relaxed selection, Tyler John Larsen
Tertiary Lymphoid Tissue in the Urinary Bladder of Aging Mice and Women, Marianne Morris Ligon
SIK3 & Wnk signals through Fray to regulate glial K+ buffering and seizure susceptibility in Drosophila models of hyperexcitability, Lorenzo Laronn Lones
Overcoming genetic heterogeneity in glioblastoma by targeting transcriptional dependencies, Tatenda Mahlokozera
Understanding the Influence of Individual-level Sources of Pathology Variation on Neuroimaging Measures of Alzheimer Disease, Austin Andrew McCullough
Cooperation and Conflict in the Social Amoeba Dictyostelium discoideum and its Paraburkholderia Endosymbionts, James Medina
Insights Into the Non-Osmoregulatory Function of a Pollen-Specific Mechanosensitive Ion Channel, Kari Miller
Emerging insights into a role for Topoisomerase IIB and Methyl-CpG binding protein 2 in regulating neuronal transcription, Sabin Nettles
Disuse-Driven Plasticity in the Human Brain, Dillan James Newbold
Extensive Behavioral Phenotyping of Williams Syndrome Locus Relevant Mouse Models to Assess Contributions of Oxytocin and Gtf2ird1, Kayla Rose Nygaard
Analysis of Regulatory Element Variation in Autism Spectrum Disorder, Evin Mitchel Padhi
The role of endoplasmic reticulum modifications in protein export in Plasmodium falciparum, Alexander Polino
Canonical and Noncanonical Mechanisms of Resistance to Arginine Starvation in Cancer, Leonard Christopher Rogers
Exploring the Roles of the Retinoblastoma Tumor Suppressor Complex in Chlamydomonas reinhardtii Cell Cycle Control, Sarah Rommelfanger
Defining the role of rare genetic variants that drive risk and pathogenesis of Alzheimer’s disease, Matthew James Rosene
Harnessing synthetic biology to create novel protein materials for applications on the nano and macro scales, Cameron Jay Sargent
Understanding the role of involucrin in skin inflammation, Alina Schmidt
Roles of Behavioral Novelty and Organismal Energetics in the Evolution of Extreme Encephalization, Erika Laurie Schumacher
The Bidirectional Relationship between the Circadian Clock and Alzheimer’s disease, Patrick Sheehan
Molecular Characterization of Integrase-RNA Interactions and Their Role in the Replication of HIV-1 and Other Retroviruses, Christian Shema Mugisha