Theses/Dissertations from 2022
Using Proteomics to Discover New Connections in the Arabidopsis Circadian Clock, Maria Lynn Sorkin
Sex Differences in Cancer Metabolism Contribute to Sex-Specific Treatment Responses, Jasmin Inge Sponagel
Genome-wide and Targeted Screening Methods Reveal Host Antiviral Mechanisms to Limit Norovirus Infection, Meagan E. Sullender
A Universal Mechanism of G Protein Inhibition, Tyson Daniel Todd
Candida Species and Bacterial Strains in the Vaginal Microbiome, Brett Tortelli
Dysregulation of Gene Expression in Non-photosensitive Trichothiodystrophy, Brittany Townley
Mechanisms Regulating Photoreceptor Subtype Specification and Chromophore Utilization in Zebrafish, Leo Volkov
Characterizing the role of interferons in host-microbe interactions in disseminated murine norovirus infection and steady-state hematopoiesis, Forrest Walker
Mechanisms for High Light Tolerance in a Fast-Growing Cyanobacterium, Patricia Walker
Role of Circadian Rhythm and Clock Regulator REV-ERBa in Group 3 Innate Lymphoid Cells, Qianli Wang
Combining computer simulations and deep learning to understand and predict protein structural dynamics, Michael D. Ward
Characterizing Human Gut Bacterial TIR Domains In Vitro, in Gnotobiotic Mice and Malnourished Children, James Stephen Weagley
Generation, Characterization, and Treatment of Functional Zebrafish Models for Musculoskeletal Disorders, Julia Nicole Whittle
The Maintenance of CD4 and CD8 T Cell Response to Persistent Antigens, Yu Xia
Single-Cell Massively Parallel Reporter Assays, Siqi Zhao
Characterization of Large-Scale Functional Network Organization in the Human Hippocampus, Annie Zheng
VCP: A Gatekeeper for Intracellular Proteopathic Seeding, Jiang Zhu
Theses/Dissertations from 2021
Functional and therapeutic insights into Wolfram syndrome pathophysiology, Damien C. Abreu
Human PLCG2 Haploinsufficiency Results in a Novel Immunodeficiency, Joshua Brandon Alinger
A Study on the Hormonal Regulation and Novel Role of Na+ Leak Channel, Non-Selective (NALCN) in Human Myometrial Smooth Muscle Cells, Chinwendu Amazu
Transcriptional Control of Dendritic Cell Function and Development, David Alexander Anderson Iii
Genetics of Pediatric Musculoskeletal Disorders, Lilian Antunes
Dedicated Interneuronal Microcircuits Regulated by Behavioral State, Moises William Arriaga
Homeostatic T Cell Receptor Interactions with Self-Peptide Tune CD4+ T Cell Function, Juliet Marie Bartleson
The Role of Soil Microbes in Improving Tallgrass Prairie Restoration and Rare Plant Reintroduction, Rachel Ellen Becknell
Defining the epigenetic and transcriptional regulatory mechanisms by which hRSV NS1 alters host transcriptional response, Nina Rose Beri
Potentiation of TMEM16A Currents by CLCA1 in Cystic Fibrosis Airway, Kayla Berry
Understand and predict microbiome and resistome dynamics in response to perturbations across diverse populations and environments, Manish Boolchandani
The evolutionary history of Camelina Crantz (Brassicaceae) and domestication of the biofuel crop, C. sativa (L.) Crantz, Jordan Brock
Phenotyping and Preclinical Meta-Analysis of Behavioral Outcomes from Complete Freund’s Adjuvant-Induced Inflammatory Pain in the Rodent Hind-paw, Dominika J. Burek
Association of Structural Variation (SV) with Cardiometabolic Traits in Finns, Lei Chen
RhoA Mediated Juxtacrine Regulation of Glucagon Secretion, Yong Hee Chung
Understanding the Roles of DNA Methylation and MeCP2 in Neuronal Enhancer Control, Adam Clemens
Dissecting the Molecular Mechanism of Familial Cardiomyopathies, Sarah Ruth Clippinger Schulte
Functional Interrogation of JAK2 and ASXL1 Mutations in Myeloproliferative Neoplasms, Taylor Brost Collins
Deep Multi-omics Investigations Elucidate Novel Oncogenesis Paradigms, Therapeutic Targets, and Mechanisms of Treatment Resistance in Cancer, Daniel Cui Zhou
Modeling Small Molecule Metabolism in Human Liver Microsome to Better Predict Toxicity Risk, Na Le Dang
Surveillance and dynamics of bacteria and resistance genes in humans and hospitals, Alaric Wences D'Souza
Polygenic and Transcriptomic Studies in Neurodegeneration: Towards More Precise Medicine., Umber Dube
The Effects of Molecular Chaperone Modulation on Protein Folding, Prion Formation, and Prion Propagation in Saccharomyces cerevisiae, Leeran Blythe Dublin Ryan
C. elegans Response to Cadmium Toxicity, Brian James Earley
Investigating the Integration-Independent Role of HIV-1 IN in the Viral Life Cycle, Jennifer Elliott
Protein Synthesis Adaptation to the AU-Rich Transcriptome of Plasmodium falciparum, Jessey Lee Erath
Understanding Immune Responses with Single-Cell RNA Sequencing and CyTOF Across Different Diseases and Model Organisms, Ekaterina Esaulova
Role of 4R tau in astrocyte-mediated neuronal toxicity and the progression of neurodegenerative disease, Lubov Alexandra Ezerskiy
Testing Janzen’s Physiological Barrier Hypothesis Through Experimental Evolution and Biogeographic Studies on Sister Species Pairs, Vincent John Fasanello
Regulatory Effects of the E. coli RecBCD Nuclease Domain on DNA Unwinding Kinetics, Nicole Fazio
SLO2.1 channels: a new molecular mechanism to regulate uterine excitability, Juan Jose Ferreira
Computational Approaches for Screening Drugs for Bioactivation, Reactive Metabolite Formation, and Toxicity, Noah Flynn
Identifying Subpopulation-level Methylation Patterns in Hematological Malignancies, Jerry Fong
The Regulation of Plasmodium falciparum Metabolism by Haloacid Dehalogenase Proteins, Philip Frasse
Sex Differences in the Role of Cornichon Homolog-3 on Spatial Memory and Synaptic Plasticity, Hannah Elizabeth Frye
Analysis of Structural Variation and mtDNA Copy Number in Finns, Liron Ganel
The Genetic Basis of Adaptation to Environmental Stress in Two Grass Genomic Model Systems, David Mitchell Goad
Regulation of genome architecture by chromatin remodeling in the brain, Jared Vega Goodman
The Role of CD53 in Hematopoietic Development, Stress, and Malignancy, Zev Joshua Greenberg
Single-Cell Resolution Mechanistic Analyses of Direct Lineage Reprogramming, Chuner Guo
Understanding the Molecular Mechanisms of Photoferrotrophy and Phototrophic Extracellular Electron Uptake, Dinesh Gupta
Thermodynamics and Conformational Heterogeneity of RecBCD Binding to DNA Ends, Linxuan Hao
Linking Neuronal Protein Phosphatase 2A to the DLK Stress Kinase Signaling Cascade, Margaret Hayne
Dendritic Processing and Efficient Coding in the Retina, Jen-Chun Hsiang
The Roles of Capsular Polysaccharides and Diet in the Immune Response to a Bacteroides thetaiotaomicron Antigen, Samantha Hsieh
Dissecting the Role and Regulation of Transcription Factor Zeb2 in Hematopoiesis, Xiao Huang
The immunoregulation of autoimmune diabetes, Hao Hu
Retinal Ganglion Cells Underlying Visual Perception and Predation in Mice, Keith Patrick Johnson
Method Development for Enhancing Sensitivity of Dynamic Nuclear Polarization Nuclear Magnetic Resonance Spectroscopy for Structural Studies of PKC-Drug Interactions, Patrick Terrence Judge
Etv2/Myct1 axis in the regulation of tumor angiogenesis and anti-tumor immunity, Ashraf Ul Kabir
Cancer Epigenome Reprogramming, Jennifer Ann Karlow
Copper-mediated Regulation of a Traditional Iron Uptake System in Uropathogenic Escherichia coli., George Lwanga Katumba
Quantitative Characterization of Microbial Ecologies in Dysbiosis and Infection, Eric Keen
The Role of Excited States in Determining β-lactamase Function and Bacterial Fitness, Catherine Rae Knoverek
Influence of Aging and Cerebrovascular Disease on Neuroimaging Measures of Alzheimer Disease, Lauren Nicole Koenig
Gut Reactions: Quantitative Predictions of the Responses of Human Gut Microbiota to Medical Interventions, Amy Elizabeth Langdon
Stem Cell Models to Study the Regulation of Human Cortical Development and Its Disruption in Neurodevelopmental Disorders, Emily Megan Alexandra Lewis
Identify Genetic and Epigenetic Abnormalities Associated with Therapeutic Vulnerability in Human Cancers, Wen-Wei Liang
Regulation of transcription factor binding specificity: from binding motifs to local DNA context, Jiayue Liu
Vestibulospinal circuit in the larval zebrafish, Zhikai Liu
Type I Interferon Regulation of Chikungunya Virus Pathogenesis, Marissa Christine Locke
Regulation, Architecture, and Function of the Type VI Secretion System of Acinetobacter baumannii, Juvenal Lopez
The Phylogeography of Rare Central Tennessee Glade Endemics Trifolium calcaricum and Viola egglestonii, Rachel Ann Lyman
Genetic Effects Mediated Through Epistatic Networks Onto Metabolic Traits, Juan Francisco Macias-Velasco
Transcriptional and Epigenetic Regulation of Cerebellar Development and Function, Shahriyar Majidi
Dissecting the neural circuits mediating pain-induced negative affect and drug-seeking behaviors, Tamara Markovic
Deep Learning Deleterious Small Molecule Biochemistry from the Lab to the Clinic, Matthew Matlock
Investigation of IFNγ-induced Control of Intracellular Pathogens, Michael Mcallaster
Ascension and Adhesion of Uropathogenic Escherichia coli during Pyelonephritis, Lisa Kristine McLellan
Modularity of Feedback for State-Dependent Guidance of Navigation in Mouse Visual Cortex, Andrew M. Meier
Developments in Proteomics, Trans-Splicing Technology And Endogenous Transcript Manipulation, Justin Alexander Melendez
The Role of Subclonal Gene Mutations During Progression from Myelodysplastic Syndrome to Secondary Acute Myeloid Leukemia, Andrew John Menssen
A Novel Function of Plasmacytoid Dendritic Cells in Regulating Type 2 Immune Responses, Hannah Leigh Miller
Prodrug Activation in Staphylococci and the Implications for Antimicrobial Development, Justin J. Miller
Exploring β-cell Function and Heterogeneity in Obese SM/J Mice, Mario Alejandro Miranda
Deconvolving Genomic Regulatory Heterogeneity with Self-Reporting Transposons, Arnav Moudgil
The roles of plasmepsins IX and X in malaria parasite biology, Armiyaw Sebastian Nasamu
The evolving mammalian 3D epigenome, Mayank Choudhary Nishikant Choudhary
Metabolic Control and Immune Barriers of Hematopoietic Stem Cells, Hannah Pizzato
Regulation of Host-Microbe Interactions in Autoimmunity and Antiviral Immunity by Cytosolic Nucleic Acid Sensing and Interferon Signaling, Derek Jerome Platt