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Theses/Dissertations from 2020

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In Vivo Mechanisms of Natural Killer Cell Tolerance, Michael Bern

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Electrophysiology of the Inner Retina in Health and Disease: EAAT5 in the Rod Bipolar Cell and Oscillatory Potentials in Diabetes, Gregory William Bligard

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Transcription Factor-Mediated Epigenetic Regulation in the Healthy Brain and Neurological Disease, Alexander J. Cammack

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The Good, The Brown, and The Healthy: Understanding Non-Thermogenic Brown Adipose Function in Obese Mice, Caryn Nicole Carson

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Regulation of Yolk Microtubule Dynamics by Dachsous Cadherins, Gina Danielle Castelvecchi

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Mitochondrial Morphology, Oxidative Stress Resistance, and Pathogenesis in Cryptococcus neoformans, Andrew Lee Chang

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Characterizing the relationship between gut microbiota development and healthy growth, Hao-Wei Chang

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Nonsense Mediated RNA Decay Promotes Survival of Cells with Defective Splicing, Abigael Jeruto Cheruiyot

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The Role of ESCRT-III-like Subunit IST1 in Membrane Trafficking Pathways, Amy Kate Clippinger

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The role of CDX4 during patterning of definitive hemogenic mesoderm, John Philip Creamer

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Dendritic Cell Development and Function, Vivek Durai

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Structural Mechanism of Poxvirus Sabotage of T-cell Costimulation, Jabari Issa Elliott

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Advances in the Understanding of Auxin Signaling Through Indirect Mechanisms, Ryan Joseph Emenecker

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The Enzymatic Function of the TIR domain: From Axon Degeneration to Innate Immunity, Kow Essuman

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The Decision Maker: Understanding the role of IFRD1 in urothelial plasticity and regeneration, Bisiayo Erionmwon Fashemi

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Post-Lysosomal Cholesterol Trafficking: Novel Tools and Insights, Mckenna Rae Feltes

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Multi-omics Integration for Gene Fusion Discovery and Somatic Mutation Haplotyping in Cancer, Steven Mason Foltz

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Cognitive Recovery in the Post-Infectious CNS, Charise Joy Garber

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The Role of the Circadian Clock Protein Rev-erba in Neuroinflammation & Synaptic Health, Percy Griffin

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FGF18 in Postnatal Lung Development, Andrew Hagan

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A mechanistic and genomic analysis of molluscum contagiosum virus immune evasion, Ian Benjamin Harvey

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Joint Estimation of Perceptual, Cognitive, and Neural Processes, Katherine Heisey

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Developing Tools for Identifying Tissue-Specific Epigenetic Marks and Predicting DNA hydroxy/methylation, Yu He

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Effects of agonistic anti-CD137 antibody on chikungunya virus infection and B cell responses, Jun Hong

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Identification and Characterization of a Novel Non-homologous End Joining Factor MRI, Putzer Joseph Hung

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The Role of Apolipoprotein E in Alzheimer Disease: From Therapy to Mechanism, Tien-Phat Vuong Huynh

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Pathophysiology and proteogenomics of post-infectious and post-hemorrhagic hydrocephalus in infants, Albert M. Isaacs

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Epigenetic Dynamics in Normal and Disease Models, Hyo Sik Jang

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Investigating the Role of Genetic Variants and Environmental Factors in the Trajectory of Substance Use Disorders, Linda Johnson

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Conformational Basis and Small Molecule Antagonists of E. coli Adhesion to the Urinary Tract, Vasilios Kalas

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Structural and Functional Insights into Alphavirus-Host Interactions, Arthur S. Kim

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Molecular Insights into Microbial Adhesion, Roger Davies Klein

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A Neuromodulatory Circuit Controls Glial Potassium Buffering to Regulate Neuronal Excitability in Drosophila melanogaster, Hailun Li

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Understanding the Molecular Pathogenesis of Retinal Neurodegeneration, Jonathan B. Lin

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Notch-Mediated Regulation of Atrial Arrhythmogenesis, Catherine Lipovsky

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Pathophysiology and Treatment of Murine Globoid Cell Leukodystrophy, Yedda Li

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Delineating the Role of MiR-124 for the Activation of Neuronal Program, Ya-Lin Lu

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Metabolic Requirements of NK Cell Responses to Viral Infection, Annelise Yoo Mah-Som

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Developmental Principles of Sensorimotor Coding in the Mammalian Cerebellum, Kelly Hill Markwalter

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Plasticity ensures robust cell wall metabolism in Escherichia coli, Elizabeth A. Mueller

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Modeling HER2 Mutations in Colorectal Cancer using a HER2 Transgenic Mouse Model and Gastrointestinal Organoids, Elisa Murray

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Neuroimmunologic Regulation of Chronic Itch, Landon Kyle Oetjen

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Effects of Toxoplasma gondii Infection on NK Cells and ILC1s, Eugene Park

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Life of Tau: Oligomerization, CNS Extracellular Clearance and Role as Plasma Biomarker, Tirth Patel

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Genomic analysis of diverse bacterial pathogens, Robert Potter

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Elucidating the Effect of Myopathy-Causing Mutations and Second-Site Suppressors on Client Processing by J-Domain Proteins, Melanie Y. Pullen

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Signaling Mechanisms in Adaptive Immunity, Saravanan Raju

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Transcriptional and Epigenetic Regulation of Cerebellar Development and Function, Naveen C. Reddy

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Genetic and Functional Characterization of Novel Host Factors Regulating Virus Infection in Caenorhabditis elegans, Luis Enrique Sandoval

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Understanding emerging biomarkers and lifestyle factors in aging and Alzheimer disease, Stephanie Schultz

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Regulation and Function of TREM2-dependent Pathways in Neurodegeneration, Wilbur Madison Song

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Bumpy Road Ahead: Overcoming DNA Replication Obstacles One Barrier at a Time, Melanie Anne Sparks

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Mechanisms of Cross-Presentation by cDC1s, Derek James Theisen

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Epigenetic and Signaling Pathways Regulating the Maintenance of CD8 T Cell Identity and Function, Daniel Verbaro

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Engineering Natural Competence into the Fast-growing Cyanobacterium Synechococcus elongatus UTEX 2973, Kristen Elizabeth Wendt

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Development of an in vitro Culture System for Cryptosporidium parvum, Georgia Wilke

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FGF20 in Olfactory System and Cochlea Development, Lu Morgan Yang

Theses/Dissertations from 2019

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Molecular Regulation of Vertebrate Pigmentation and Stem Cell Quiescence in Larval Zebrafish, James Randolph Allen

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A Combinatorial Approach of Ionomics, Quantitative Trait Locus Mapping, and Transcriptome Analysis to Characterize Element Homeostasis in Maize, Alexandra Asaro

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Development of Enteric Neurons and Muscularis Macrophages, Marina Avetisyan

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Understanding the Transcriptional Mechanisms Underlying Dendritic Cell Development, Prachi Bagadia

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The Role of Mitofusins in the Osteoclast Lineage, Anna Ballard

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The Role of Tumor Stromal Discoidin Domain Receptor 2 (DDR2) in Breast Cancer Metastasis., Samantha Van Hove Bayer

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Brain Blood Flow and Metabolism: Variable Relationships in Altered Metabolic States, Tyler M. Blazey

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A Noncanonical Function of the Telomerase RNA Component in Human Embryonic Stem Cells, Kirsten Ann Brenner

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Activation and Regulation of the ALKBH3-ASCC Alkylation Repair Pathway, Josh Brickner

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Defining Gastric Epithelial Cell Population Dynamics At Homeostasis And Following Injury, Joseph Ronald Burclaff

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Identifying Novel Regulators of Double Strand Break Repair and Replication Fork Protection, Andrea Karl Byrum

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Multi-omic Understanding of the Evolution of Xenobiotic Tolerance in Bacterial Isolates and Communities, Tayte Paul Campbell

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Beta-diversity, Environmental Change, and the Stability of Regional Ecosystems, Christopher P. Catano

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The Impact of Structural Variation on Human Gene Expression, Colby Chiang

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From Schwann Cells to Melanoma: Neural Crest Derived Cells in Development and Disease, Rebecca Lynng Cunningham

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The Role of Alternative NF-kB Signaling in Osteogenesis, Jennifer Davis

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Transcriptional Regulation of Adipose Tissue Development by PexRAP and Med19, John Dean

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Effects of Microbiota-Directed Fiber-Enriched Food Prototypes in Gnotobiotic Mice and Humans, Omar Delannoy-Bruno

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The Biomedical Application of Chimeric Antigen Receptor T cell Therapy, Jessica Devenport

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Dissemination of the apicomplexan parasite, Toxoplasma gondii, Lisa L. Drewry

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The Autophagy-Lysosome System in Cardiometabolic Disease, Trent Evans

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Characterizing the Humoral Response to Flavivirus Infection, Estefania Fernandez

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High-Density Diffuse Optical Tomography During Passive Movie Viewing: A Platform for Naturalistic Functional Brain Mapping, Andrew Kelsey Fishell

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High-Density Diffuse Optical Tomography During Passive Movie Viewing: A Platform for Naturalistic Functional Brain Mapping, Andrew Kelsey Fishell

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Genomic Signatures of Conflict and Cooperation in Plants and Social Amoebae, Katherine Sylvia Geist

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Discoidin Domain Receptor 2 as a Therapeutic Target in Breast and Ovarian Cancer, Whitney Grither

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Understanding the Physiology of Extracellular Electron Uptake in Purple Nonsulfur Bacteria, Michael Singh Guzman

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Regulation of the Yeast Cell Cycle Checkpoint Kinase Tel1 at Double-Strand DNA Breaks and at Telomeres, Sarem Hailemariam

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T cell Immunity in Pancreatic Cancer is Undermined by Dendritic Cell Dysfunction, Samarth Hegde

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The Role of Rifampicin Resistance Mutations in Host Immune Modulation by Mycobacterium tuberculosis, Nicole Christine Howard

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Mapping and Functional Analysis of cis-Regulatory Elements in Mouse Photoreceptors, Andrew Hughes

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The Transcription Factor Bhlhe40 Regulates Tissue-Resident Macrophages and Type 2 Immunity, Nicholas N. Jarjour

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Coordinated Control of Carbon Metabolism in Plasmodium falciparum, Andrew James Jezewski

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From Single Cells to Human Disease: High-resolution Phenotyping of Male Infertility Models Using Single-cell RNA Sequencing, Min Jung

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Investigation of immunostimulatory commensal bacteria in health and immune mediated disorders, Sunaina Khandelwal

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Aging of the Reproductive System and of Germline Stem Cells in Caenorhabditis, Zuzana Kocsisova

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Determining the Genetic Contributions of the Williams Syndrome Critical Region to Behavior Using Mouse Models and Human Genetics, Nathan David Kopp

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Determining the Genetic Contributions of the Williams Syndrome Critical Region to Behavior Using Mouse Models and Human Genetics, Nathan David Kopp

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Molecular Mechanisms Responsible for Functional Cortical Plasticity During Development and after Focal Ischemic Brain Injury, Andrew Wiggen Kraft

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Mesothelium-derived factors shape tissue resident macrophage, Chin-Wen Lai

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The Degenerating Star Clock: Circadian Clock Regulation of Astrogliosis and Implications for Alzheimer’s Disease, Brian Vincent Lananna

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A Molecular Logic of Sensory Coding Revealed by Optical Tagging of Physiologically-Defined Neuronal Types, Donghoon Lee

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A Molecular Logic of Sensory Coding Revealed by Optical Tagging of Physiologically-Defined Neuronal Types, Donghoon Lee