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Theses/Dissertations from 2015

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Molecular and Computational Methods for Cellular State Control, Drew Groves Michael

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Endogenous Protection in Subarachnoid Hemorrhage, Eric Milner

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Transcriptional Regulation of the Endoplasmic Reticulum in Dedicated Secretory Cells, Benjamin David Moore

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Spinal k-Opioid Receptor Activation Attenuates Itch by Inhibiting Gastrin-releasing Peptide Receptor Function, Admire Munanairi

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Behavioral and fMRI-based Characterization of Cognitive Processes Supporting Learning and Retrieval of Memory for Words in Young Adults, Binyam Nardos

Molecular Basis of the Biogenesis and Function of the Enterococcus faecalis Endocarditis- and Biofilm-Assiciated Pilus, Hailyn Nielsen

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Characterizing Regulatory T Cell Differentiation to Bacterial Antigens in the Gut, Katherine Nutsch

HIV Neurodegeneration in the HAART Era, Mario Ortega

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The Effects of HPA Axis Genetic Variation and Early Life Stress on Cortisol Levels in Preschool Age Children and on Amygdala and Hippocampus Volumes, Reactivity, and Connectivity at School Age, David Pagliaccio

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Molecular Characterization of a Novel, Highly Protective Combination Monoclonal Antibody Therapy against Chikungunya Virus, Pankaj Pal

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Adaptive Mechanisms of Niche Remodeling in Streptococcus pyogenes, Elyse Paluscio

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Neural Mechanisms of Working Memory Cortical Networks, Charalampos Papadimitriou

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Distribution and Dissemination of Antibiotic Resistance Genes between Microbiota in Antibiotic-Naïve and Resource-Poor Settings, Erica Courtney Pehrsson

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Functional Consequences of CD4+ T Cell Receptor Ligation in the Immune Response to Listeria monocytogenes, Stephen Phillip Persaud

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β-Lactamase Gene Exchange within the Enterobacteriaceae, Mitchell William Pesesky

Differential Encoding of Spatial Information among Retinal ON Cone Bipolar Cells, Robert Joseph Purgert

Characterizing Rare Genetic and Epigenetic Variation in Complex Phenotypes, Enrique Ivan Ramos

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DNA Damage Responses Regulate Macrophage Function During Innate Immune Responses, Abigail Rodriguez Morales

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Viral and Innate Immune Factors Controlling Disease Susceptibility During Chikungunya Virus Infection, Anjali Rohatgi

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Senescent Fibroblasts Drive Tumorigenesis Through the Establishment of an Immunosuppressive Microenvironment, Megan Kiel Ruhland

Habitat Size Mediates the Effects of Environmental Factors on Species Richness, Matthew Scott Schuler

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Understanding Escherichia coli Urinary Tract Infection: A Niche Perspective, Drew Joel Schwartz

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Escherichia coli Iron Acquisition Paradigms and Host Responses in the Human Urinary Milieu, Robin Reid Shields-Cutler

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Functional Characterization of Putative Rab Geranylgeranyltransferase Subunits in Arabidopsis thaliana, Wan Shi

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Dissecting Intracellular Signaling and Affective Behavior Using Optically Active GPCRs, Edward Ryszard Siuda

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Identifying the Functions of ILC3 in Intestinal Immunity, Christina Song

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Mitochondrial Dynamism and Mitochondrial Quality Control in the Heart, Moshi Song

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Impaired Gut Microbial Community Development in Undernourished Children, Sathish Subramanian

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Flap Endonuclease 1 Promotes Telomere Replication and Stability by Distinct Mechanisms on the Leading and Lagging Strands, Daniel Cole Teasley

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Excessive Complement Activation Due to Genetic Haploinsufficiency of Regulators in Multiple Human Diseases, Michael Triebwasser

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Transmission Dynamics of Antibiotic Resistance Genes Between Human-associated and Environmental Microbial Communities, Pablo Tsukayama

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Mechanisms Underlying Memory Deficits Following West Nile Virus Neuroinvasive Disease, Michael John Vasek

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A Gnotobiotic Mouse Model for Studying the Effect of Human Gut Community Ecology on a Pathobiont, Bacteroides fragilis, Vitas Wagner

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BTB-ZF Regulators of Long-Term Antibody Responses, Yinan Wang

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Mechanisms of High Zinc Tolerance, Sensing, and Homeostasis in C. elegans, Kurt Warnhoff

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Single-chain RANKL Provides Insights into RANK Receptor Oligomerization and a Novel Approach to Osteoclast Inhibition, Julia Therese Warren

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Molecular Mechanisms of Axon Growth and Regeneration, Dana Watt

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The U1A/U2B"/SNF Family of RNA Binding Proteins: Evolution of RNA Binding Specificity and Contributions of Heterotropic Linkage to snRNP Protein Partitioning, Sandra Gisela Williams

Retinoids and Mitochondrial Effects on Enteric Nervous System Development, Structure, and Function, Elizabeth Copeland Wright-Jin

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Factors Contributing to Yeast Prion Generation and Propagation, Siyao Xing

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The Mechanism and Regulation of Mammalian Photoreceptor Dark Adaptation, Yunlu Xue

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Genetic and Cellular Studies of The Podocyte in Focal Segmental Glomerulosclerosis, Haiyang Yu

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Human Immunodeficiency Virus Type 1 Envelope Protein Interaction with Host Cell Coreceptor C-X-C Chemokine Receptor Type 4, Jie Zhang

Theses/Dissertations from 2014

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Novel Role of CHK2 in the Intrinsic and Extrinsic Apoptosis Pathway, Anurag Agarwal

The Role of GRA7, a Component in the ROP18 Protein Complex, in Toxoplasma gondii, Aditi Alaganan

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Contribution of the Microenvironment in Bone Resident Cancer: the Role of Thrombospondin-1 in Bone and Risk Loci Contributing to Multiple Myeloma, Sarah R. Amend

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Genetic and Epigenetic Determinants of Transcription in the Divergent Eukaryote Leishmania major, Britta Anderson

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Failsafe Mechanisms Coordinate Cell Division and the Initiation of DNA Replication in Bacteria, Heidi Ann Arjes

Genetic Architecture of Left Ventricular Hypertrophy, Ruteja A. Barve

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Modulating Amyloid Beta Clearance by Altering Cellular and Whole Brain Apolipoprotein E Metabolism, Jacob Martin Basak

Defining the Peripheral and Thymic Niche of Regulatory T Cells, Jhoanne Lynne Bautista

PUMA and BIM Are Required for Oncogene Inactivation-Induced Apoptosis and Anoikis, Gregory Bean

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Dynamic Responses at the Barrier Epithelium, Katherine Beebe

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Axonal Damage in Repetitive Concussive Traumatic Brain Injury: Characterization and Contributing Factors, Rachel Bennett

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Oxygen Polarography in the Awake Macaque: Bridging BOLD fMRI and Electrophysiology, William Joseph Bentley

The Role of Oxysterol-Membrane Effects on Cholesterol Activity and Homeostasis, Agata Agnieszka Bielska

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Strategies for Computational Protein Design with Application to the Development of a Biomolecular Tool-kit for Single Molecule Protein Sequencing, Benjamin Borgo

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Transcriptional Analysis of Reciprocal Tumor-Microenvironment Interactions in Glioblastoma, Michael Brooks

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Genomic Analysis of Human Spinal Deformity and Characterization of a Zebrafish Disease Model, Jillian Gwen Buchan

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An Exported Malaria Protein Regulates Glucose Uptake During Intraerythrocytic Infection, Tamira K. Butler

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Characterization of the Role of R7-RGS Proteins in Mammalian Retina and Vision, Matthew D. Cain

Structural Elucidation of [RNQ+] prions Transmissible Infectivity, Donell Carey

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Murine Cytomegalovirus Encodes Proteins that Regulate Viral Late Transcription, Travis Chapa

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Mechanisms Regulating the Self-Renewal and Differentiation of Nephron Progenitors, Shuang Chen

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Regulation of Fluid-phase Uptake in Podocytes by Albumin-associated Lipids, Jun-Jae Chung

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The Role of FGF Signaling in the Regulation of Adult Murine Cardiomyocyte Contractility and Pathologic Hypertrophy, Sarah Nicole Cilvik

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Antisense Reduction of the Protein Tau Attenuates Neuronal Hyperexcitability and Permits Clearance of Intraneuronal Tau Accumulations in vivo, Sarah Lorraine DeVos

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Hedonics, Reward Prediction, and Reinforcement Learning in Schizophrenia: Relationships to Anhedonia and Avolition, Erin Dowd

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Modulation of NMDA Receptor Activity During Physiological and Pathophysiological Events, Christine Marie Emnett

Manipulation of Inflammatory Processes by a Poxvirus-Encoded Decoy Receptor, Megan Leigh Epperson

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The Regulation of Glucose Metabolism during Osteoblast Differentiation, Emel Esen

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Serotonergic Signaling Pathways that Suppress Amyloid Beta in Mouse Models of AD, Jonathan Robert Fisher

Identification and Characterization of Novel Caenorhabditis Nematode Viruses, Carl Joseph Franz

Merlin Regulation of Mouse Spinal Cord Neural Precursor Cell Function, Cynthia Garcia

Influenza Induces Chronic Inflammatory Disease, Michael Edward Hinojosa

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LIA4 and HP1-like Proteins Facilitate DNA Elimination During Tetrahymena Macronuclear Development, Scott Horrell

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Negative Regulation of the Hippo Pathway by the Ajuba LIM Proteins, Radhika Jagannathan

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The Genetic Basis of Susceptibility to Therapy-related Leukemia in Mice, Megan Janke

snoRNA U17 as a Novel Regulator of Cholesterol Homeostasis, Sarah Jinn

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Identification of Functional Variants in Alzheimer's Disease-Associated Genes, Sheng Chih Jin

Rare, De Novo, and Common Variants in CARD14 in Psoriasis, Catherine Teresa Jordan

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DAPK3 Suppresses Mammary Acini Morphogenesis and is Required for Mouse Development, Brandon Kocher

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Studies on the Mislocalized Exonuclease TREX1 that Causes a Systemic Vasculopathy, Parul Harish Kothari

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MicroRNAs in ALS: Defining Cell-Type Specific Expression, Developing Methods to Modulate MicroRNAs in vivo, and Identifying Novel Therapeutic Targets, Erica Danielle Koval

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The Role of Hspa9 in Mouse Hematopoiesis and IL-7 Receptor Signaling, Kilannin Krysiak

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cis-Regulation in the Mammalian Rod Photoreceptor, Jamie C. Kwasnieski

Imaging of Cancer Immunoediting, Siu Kit Lam

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Cold Shock Domain Proteins in Normal and Leukemic Hematopoiesis, Cheng Li

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Processing Submillisecond Timing Differences in a Model Electrosensory System, Ariel Maia Lyons-Warren

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Primary Structure and Solution Conditions Determine Conformational Ensemble Properties of Intrinsically Disordered Proteins, Albert Hsuan-Han Mao

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The Nrl Photoreceptor Cell Fate Switch: Endogenous Regulation and Therapeutic Applications, Cynthia Montana

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Host-Microbial Interactions that Modulate Luminal IgA, Clara Moon

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Dual Roles of Interferon Stimulated Gene-15 During Respiratory Virus Infection, David James Morales

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Broad Ligand Specificity in the Small Multidrug Resistance Transporter EmrE, Emma Antonina Morrison

Computational Tools to Expand the Coverage of Metabolite Profiling via LC-MS/MS, Igor Nikolskiy

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How CD4+ T Cells Recognize Allostimulatory Peptide-MHC, Peggy Pei-wen Ni

The Role of ERK1/2 Signaling in the Peripheral Nociceptive Circuit, Daniel Edward O'Brien

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Regulation and inhibition of pro-tumorigenic microenvironments, Elise Oster Alspach

Mechanisms of Autophagy Protein Mediated Goblet Cell Secretion in the Intestinal Epithelium, Khushbu K. Patel

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Neural Correlates of Reach Planning and Execution, Thomas Pearce