Theses/Dissertations from 2022
The Role of SOXE Transcription Factors in Melanoma Initiation, Eva Tulchinsky Kramer
Contributions of Specific Retinal Circuits and Their Respective Projections to Visual Behaviors, Jenna Mackenzie Krizan
Massively Parallel Assessment of the Functional Effects of De Novo Autism Spectrum Disorder Patient-Derived Genetic Variants in 3’ Untranslated Regions, Tomas Lagunas Jr
Techniques for Spatial Analysis of C. elegans Anatomy and Reporter Expression, Nicolette Marie Laird
Inferring adaptation in social microbes from experimental evolution under relaxed selection, Tyler John Larsen
Tertiary Lymphoid Tissue in the Urinary Bladder of Aging Mice and Women, Marianne Morris Ligon
SIK3 & Wnk signals through Fray to regulate glial K+ buffering and seizure susceptibility in Drosophila models of hyperexcitability, Lorenzo Laronn Lones
Overcoming genetic heterogeneity in glioblastoma by targeting transcriptional dependencies, Tatenda Mahlokozera
Understanding the Influence of Individual-level Sources of Pathology Variation on Neuroimaging Measures of Alzheimer Disease, Austin Andrew McCullough
Cooperation and Conflict in the Social Amoeba Dictyostelium discoideum and its Paraburkholderia Endosymbionts, James Medina
Insights Into the Non-Osmoregulatory Function of a Pollen-Specific Mechanosensitive Ion Channel, Kari Miller
Emerging insights into a role for Topoisomerase IIB and Methyl-CpG binding protein 2 in regulating neuronal transcription, Sabin Nettles
Disuse-Driven Plasticity in the Human Brain, Dillan James Newbold
Extensive Behavioral Phenotyping of Williams Syndrome Locus Relevant Mouse Models to Assess Contributions of Oxytocin and Gtf2ird1, Kayla Rose Nygaard
Analysis of Regulatory Element Variation in Autism Spectrum Disorder, Evin Mitchel Padhi
The role of endoplasmic reticulum modifications in protein export in Plasmodium falciparum, Alexander Polino
Canonical and Noncanonical Mechanisms of Resistance to Arginine Starvation in Cancer, Leonard Christopher Rogers
Exploring the Roles of the Retinoblastoma Tumor Suppressor Complex in Chlamydomonas reinhardtii Cell Cycle Control, Sarah Rommelfanger
Defining the role of rare genetic variants that drive risk and pathogenesis of Alzheimer’s disease, Matthew James Rosene
Harnessing synthetic biology to create novel protein materials for applications on the nano and macro scales, Cameron Jay Sargent
Understanding the role of involucrin in skin inflammation, Alina Schmidt
Roles of Behavioral Novelty and Organismal Energetics in the Evolution of Extreme Encephalization, Erika Laurie Schumacher
The Bidirectional Relationship between the Circadian Clock and Alzheimer’s disease, Patrick Sheehan
Molecular Characterization of Integrase-RNA Interactions and Their Role in the Replication of HIV-1 and Other Retroviruses, Christian Shema Mugisha
Using Proteomics to Discover New Connections in the Arabidopsis Circadian Clock, Maria Lynn Sorkin
Sex Differences in Cancer Metabolism Contribute to Sex-Specific Treatment Responses, Jasmin Inge Sponagel
Genome-wide and Targeted Screening Methods Reveal Host Antiviral Mechanisms to Limit Norovirus Infection, Meagan E. Sullender
A Universal Mechanism of G Protein Inhibition, Tyson Daniel Todd
Candida Species and Bacterial Strains in the Vaginal Microbiome, Brett Tortelli
Dysregulation of Gene Expression in Non-photosensitive Trichothiodystrophy, Brittany Townley
Mechanisms Regulating Photoreceptor Subtype Specification and Chromophore Utilization in Zebrafish, Leo Volkov
Characterizing the role of interferons in host-microbe interactions in disseminated murine norovirus infection and steady-state hematopoiesis, Forrest Walker
Mechanisms for High Light Tolerance in a Fast-Growing Cyanobacterium, Patricia Walker
Role of Circadian Rhythm and Clock Regulator REV-ERBa in Group 3 Innate Lymphoid Cells, Qianli Wang
Combining computer simulations and deep learning to understand and predict protein structural dynamics, Michael D. Ward
Characterizing Human Gut Bacterial TIR Domains In Vitro, in Gnotobiotic Mice and Malnourished Children, James Stephen Weagley
Generation, Characterization, and Treatment of Functional Zebrafish Models for Musculoskeletal Disorders, Julia Nicole Whittle
The Maintenance of CD4 and CD8 T Cell Response to Persistent Antigens, Yu Xia
Single-Cell Massively Parallel Reporter Assays, Siqi Zhao
Characterization of Large-Scale Functional Network Organization in the Human Hippocampus, Annie Zheng
VCP: A Gatekeeper for Intracellular Proteopathic Seeding, Jiang Zhu
Theses/Dissertations from 2021
Functional and therapeutic insights into Wolfram syndrome pathophysiology, Damien C. Abreu
Human PLCG2 Haploinsufficiency Results in a Novel Immunodeficiency, Joshua Brandon Alinger
A Study on the Hormonal Regulation and Novel Role of Na+ Leak Channel, Non-Selective (NALCN) in Human Myometrial Smooth Muscle Cells, Chinwendu Amazu
Transcriptional Control of Dendritic Cell Function and Development, David Alexander Anderson Iii
Genetics of Pediatric Musculoskeletal Disorders, Lilian Antunes
Dedicated Interneuronal Microcircuits Regulated by Behavioral State, Moises William Arriaga
Homeostatic T Cell Receptor Interactions with Self-Peptide Tune CD4+ T Cell Function, Juliet Marie Bartleson
The Role of Soil Microbes in Improving Tallgrass Prairie Restoration and Rare Plant Reintroduction, Rachel Ellen Becknell
Defining the epigenetic and transcriptional regulatory mechanisms by which hRSV NS1 alters host transcriptional response, Nina Rose Beri
Potentiation of TMEM16A Currents by CLCA1 in Cystic Fibrosis Airway, Kayla Berry
Understand and predict microbiome and resistome dynamics in response to perturbations across diverse populations and environments, Manish Boolchandani
The evolutionary history of Camelina Crantz (Brassicaceae) and domestication of the biofuel crop, C. sativa (L.) Crantz, Jordan Brock
Phenotyping and Preclinical Meta-Analysis of Behavioral Outcomes from Complete Freund’s Adjuvant-Induced Inflammatory Pain in the Rodent Hind-paw, Dominika J. Burek
Association of Structural Variation (SV) with Cardiometabolic Traits in Finns, Lei Chen
RhoA Mediated Juxtacrine Regulation of Glucagon Secretion, Yong Hee Chung
Understanding the Roles of DNA Methylation and MeCP2 in Neuronal Enhancer Control, Adam Clemens
Dissecting the Molecular Mechanism of Familial Cardiomyopathies, Sarah Ruth Clippinger Schulte
Functional Interrogation of JAK2 and ASXL1 Mutations in Myeloproliferative Neoplasms, Taylor Brost Collins
Deep Multi-omics Investigations Elucidate Novel Oncogenesis Paradigms, Therapeutic Targets, and Mechanisms of Treatment Resistance in Cancer, Daniel Cui Zhou
Modeling Small Molecule Metabolism in Human Liver Microsome to Better Predict Toxicity Risk, Na Le Dang
Surveillance and dynamics of bacteria and resistance genes in humans and hospitals, Alaric Wences D'Souza
Polygenic and Transcriptomic Studies in Neurodegeneration: Towards More Precise Medicine., Umber Dube
The Effects of Molecular Chaperone Modulation on Protein Folding, Prion Formation, and Prion Propagation in Saccharomyces cerevisiae, Leeran Blythe Dublin Ryan
C. elegans Response to Cadmium Toxicity, Brian James Earley
Investigating the Integration-Independent Role of HIV-1 IN in the Viral Life Cycle, Jennifer Elliott
Protein Synthesis Adaptation to the AU-Rich Transcriptome of Plasmodium falciparum, Jessey Lee Erath
Understanding Immune Responses with Single-Cell RNA Sequencing and CyTOF Across Different Diseases and Model Organisms, Ekaterina Esaulova
Role of 4R tau in astrocyte-mediated neuronal toxicity and the progression of neurodegenerative disease, Lubov Alexandra Ezerskiy
Testing Janzen’s Physiological Barrier Hypothesis Through Experimental Evolution and Biogeographic Studies on Sister Species Pairs, Vincent John Fasanello
Regulatory Effects of the E. coli RecBCD Nuclease Domain on DNA Unwinding Kinetics, Nicole Fazio
SLO2.1 channels: a new molecular mechanism to regulate uterine excitability, Juan Jose Ferreira
Computational Approaches for Screening Drugs for Bioactivation, Reactive Metabolite Formation, and Toxicity, Noah Flynn
Identifying Subpopulation-level Methylation Patterns in Hematological Malignancies, Jerry Fong
The Regulation of Plasmodium falciparum Metabolism by Haloacid Dehalogenase Proteins, Philip Frasse
Sex Differences in the Role of Cornichon Homolog-3 on Spatial Memory and Synaptic Plasticity, Hannah Elizabeth Frye
Analysis of Structural Variation and mtDNA Copy Number in Finns, Liron Ganel
The Genetic Basis of Adaptation to Environmental Stress in Two Grass Genomic Model Systems, David Mitchell Goad
Regulation of genome architecture by chromatin remodeling in the brain, Jared Vega Goodman
The Role of CD53 in Hematopoietic Development, Stress, and Malignancy, Zev Joshua Greenberg
Single-Cell Resolution Mechanistic Analyses of Direct Lineage Reprogramming, Chuner Guo
Understanding the Molecular Mechanisms of Photoferrotrophy and Phototrophic Extracellular Electron Uptake, Dinesh Gupta
Thermodynamics and Conformational Heterogeneity of RecBCD Binding to DNA Ends, Linxuan Hao
Linking Neuronal Protein Phosphatase 2A to the DLK Stress Kinase Signaling Cascade, Margaret Hayne
Dendritic Processing and Efficient Coding in the Retina, Jen-Chun Hsiang
The Roles of Capsular Polysaccharides and Diet in the Immune Response to a Bacteroides thetaiotaomicron Antigen, Samantha Hsieh
Dissecting the Role and Regulation of Transcription Factor Zeb2 in Hematopoiesis, Xiao Huang
The immunoregulation of autoimmune diabetes, Hao Hu
Retinal Ganglion Cells Underlying Visual Perception and Predation in Mice, Keith Patrick Johnson
Method Development for Enhancing Sensitivity of Dynamic Nuclear Polarization Nuclear Magnetic Resonance Spectroscopy for Structural Studies of PKC-Drug Interactions, Patrick Terrence Judge
Etv2/Myct1 axis in the regulation of tumor angiogenesis and anti-tumor immunity, Ashraf Ul Kabir
Cancer Epigenome Reprogramming, Jennifer Ann Karlow
Copper-mediated Regulation of a Traditional Iron Uptake System in Uropathogenic Escherichia coli., George Lwanga Katumba
Quantitative Characterization of Microbial Ecologies in Dysbiosis and Infection, Eric Keen