Theses/Dissertations from 2025
Investigating Molecular Mechanisms of Meiosis and Mitosis in Cryptosporidium parvum, Abigail Kimball
Action-as-Language: Using AI to Model Behavioral Patterns and Context from EHR Workflows, Seunghwan Kim
Examining Light-Circadian Interactions in Regulation of Amyloid Plaque Pathology, Melvin William King
Novel Therapeutics for Myeloid Malignancies, Tim Kong
Dissecting the Contribution of STMN2 to ALS Pathogenesis, Kelsey Krus
New Paradigms in E. coli Hemolysin Function and Pathogenesis, Hunter Winston Kuhn
Mechanistic insights into human neuronal reprogramming and vulnerability in Huntington’s disease, Ji-Sun Kwon
Effects of Pharmacologic and Genetic Manipulation of GABA-A Receptors on Network Activity, Peter Michael Lambert
The Gene Regulatory Landscape of Proximal Tubule Sub-populations in Kidney Disease, Nicolas Ledru
Examination of protective mucosal immune responses to viral sexually transmitted infections, Aisha Lee
The 3D Genome: Investigating CO2 Driven Chromatin Dynamics and Epigenetic Reprogramming in Arabidopsis thaliana, Scott Lewis
Humoral Immune Responses following Immunization with SARS-CoV-2 Variant Vaccines, Chieh-Yu Liang
Pan-Cancer Universal Targets for Immunotherapy Resulted from Transposable Elements Activation, Yonghao Liang
Mechanisms of Voltage Gating in the Cyclic Nucleotide Binding Domain Channel Family, Jenna L. Lin
PILRα Sustains Microglial Capacity to Process Myelin in a Mouse Model of Demyelination, Kent Lin
Understanding the Effects of Genetic Variation on Maize and Pennycress Root System Architectures and Their Interaction with Nitrogen, Alexander Euway Liu
Chaperone-Usher Pathway Pili Adhesin Conformations and Inhibitors in Urinary Tract Infections, Edward Lopatto
Mechanisms of Antibody-Mediated Protection in Severe Acute Respiratory Syndrome Coronavirus 2 Infection, Samantha Mackin
Understanding Pancreatic Islet Stress Responses and Developing Strategies to Improve Transplantation Grafts, Marlie Maria Maestas
Pituitary Adenylate Cyclase Activating Polypeptide and Its Receptor as Novel Therapeutic Targets for Opioid Induced Hyperalgesia, Elizaveta Mangutov
Pituitary Adenylate Cyclase Activating Polypeptide and Its Receptor as Novel Therapeutic Targets for Opioid Induced Hyperalgesia, Elizaveta Mangutov
Elucidating Pathways in Lung Monocytes, Macrophages, and Dendritic Cells that Impact Mtb Pathogenesis, Michael Eric McNehlan
Expanding the druggable proteome by integrating deep learning with molecular simulations to predict cryptic pockets, Artur Meller
Mechanisms of MLL-rearranged Infant Leukemogenesis, Jonny Mendoza-Castrejon
Engineering Dendritic Cells with a Chimeric Antigen Receptor for Enhanced Antitumor Function, Shelby Namen
Investigating the Roles of SOX10 and ETV4 in Melanocyte and Melanoma Development, Catherine Marie Newsom-Stewart
Single-cell and spatial immunogenomics to dissect immune mechanisms in inflammatory bowel diseases and the central nervous system, Khai Mac Nguyen
Predicting, culturing, and characterizing beneficial and detrimental strains associated with plant phenotypes., Anastasiia Onyshchenko
Mechanism of unconventional IL-33 release in airway disease, Omar Osorio
Elucidating the Role of PBAF Chromatin Remodeling Subunit Arid2 in B Cell Development, Rachel Paolini
Understanding Outer Membrane Vesicle Biogenesis in Bacteroides thetaiotaomicron, Evan J. Pardue
Understanding Loss of Beta-cell Identity and Progression of Diabetes in Polygenic Mouse Models of T2DM, Sumitkumar Patel
Leveraging Biomolecules to Illuminate the Landscape of RNA in Cells and Tissues, Alexandria Quillin
The role of the poly-N repeat in the Plasmodium falciparum histone acetyltransferase protein, PfGCN5, Kely Johana Rubiano Cardona
Characterization of Long-Noncoding RNAs in Prostate and Pancreatic Cancer Through Single Cell Transcriptomics, Debanjan Saha
Exploring the Thermal Physiology Evolution Across Mountain Slopes, Jhan Carlos Salazar Salazar
Robust Embeddings of Genetics, Anatomy, and State Decoded from a Neuron’s Activity, Aidan Schneider
Optimizing Massively Parallel Reporter Assays for In Vivo Neurogenomics: Tools to Decode Enhancer Function in the Brain, Din Selmanovic
Mechanisms of ssDNA Gap Resection in BRCA1-proficient and -deficient Cells, Isabelle Seppa
ACLY Is Required for NK Cell Effector Function by Regulating the Epigenome, Stacey Sohn
Depalmitoylation regulates metabolism and mitochondrial function, Sarah Lilly Speck
Needle in the Z-stack: Mapping the 3D Transition to Malignancy, Erik Storrs
Parental Guidance Suggested: Genetic, Epigenetic, and Environmental Factors Shape Allele-Specific Gene Regulation in Metabolic Traits, Celine Louise St. Pierre
Plant-Microbe Interactions Across Scales: Diversity, Disease, and Stress in Herbaceous Plant Communities, Philippa Tanford
Oxycodone Self-Administration Modulates Ventral Pallidal Neuron Activity and Plasticity, Jessica Tooley
The Role of IL-33 in Itch, Anna M. Trier
Cortical Functional Organization in Early Childhood, Jiaxin Tu
Computational Dissection of Innate Immune Cell States: Tissue-Driven Heterogeneity Across Human Development, Alina Ulezko Antonova
Direct and Indirect Factors Render LPS Essential to Gram-negative Bacterial Physiology, Ryan Adam Valdez
Mitochondria Transfer-based Therapy for the Mitochondrial Disease Leigh Syndrome, Stella Varnum
Investigating the effects of maternal separation on the locus coeruleus and negative affective behaviors in adulthood, Chayla Rene Vazquez
Investigating the interplay of genetic factors and viral infections in type 1 diabetes pathogenesis, Daniel Andre Veronese-Paniagua
Efficient packaging of HIV-1 genomes via recognition of its adenosine-rich content by a heterologous RNA-binding domain, Hung Ryan Vuong
Acquisition Algorithms for Protein Mass Spectrometry and Their Application to Clinical Proteomics, Nathan Wamsley
Advancing Precision Treatment of Multiple Myeloma with Single-Cell and Spatial Immune Profiling, Julia Wang
Dominant tree species as a driver of forest herb community assembly: The peculiar case of pawpaw (Asimina triloba), Anna Wassel
Proteogenomic Analysis to Inform Causal Gene Prioritization for Human Disease, Daniel Western
Leveraging arginine catabolism to treat metabolic complications, Yiming Zhang
Investigating the Genetics and Genomics of Vein of Galen Malformations, Shujuan Zhao
Theses/Dissertations from 2024
Cellular and Molecular Basis of CD4+ T Cell Help at the Effector Phase During Immunotherapy of MHC-II Negative Tumors, Samuel Oche Ameh
Aging Antiviral Immunity In The Central Nervous System: Mechanisms And Implications, Artem D. Arutyunov
Mechanisms of uropathogenic E. coli reservoir formation in the gastrointestinal tract, Philippe Nimma Azimzadeh
Mechanisms of uropathogenic E. coli reservoir formation in the gastrointestinal tract, Philippe Nimma Azimzadeh
Avian Adaptation to Thermal Gradients, Justin Wheeler Baldwin
Interleukin-1α and Leukemia Inhibitory Factor Promote Cancer-Induced Extramedullary Hematopoiesis, Derek Arthur George Barisas
Inducible CRISPR-Targeted ‘Knockdown’ of Human Gut Bacteroides in Mice Reveals Glycan Utilization Strategies, Zachary Beller
Development and Structure of Spinal Interneuron Connectivity in Larval Zebrafish, Saul Bello Rojas
A Filter-Based Model of Visual Recognition, Olivia Rose Bockler
Employing Single-Nucleus RNA-Seq to Uncover Genetic Factors of Alzheimer Disease, Logan Brase
Mechanism of Impaired CD8+ T Cell Activation During Ross River Virus Infection, Christopher Bullock
Predicting Cell Fate Using Single-Cell State and Lineage Information, Emily Grace Butka
Gnotobiotic Mouse Models For Characterizing the Role of the Microbiota On Undernutrition and Early Postnatal Brain Development, Alexandra Elizabeth Byrne
Developing tools to study the effect of the mechanical environment on plant cell growth and morphogenesis, Ryan Calcutt
Accumbal Plasticity and Associated Behavioral Adaptations in the Spared Nerve Injury Model of Chronic Neuropathic Pain, Yu-Hsuan Chang
Epigenetic Dynamics in Zebrafish Development and Regeneration, Yujie Chen
The Role of MiR-34a in Pathological Neovascularization as Seen in Age-Related Macular Degeneration, Jason Colasanti
Sustainable Plastics from Plastic metabolisms: Leveraging Purple Non-sulfur Bacteria for Polyhydroxyalkanoate Synthesis, Eric Michael Conners
Discovery and Functional Characterization of Proteins Encoded by Annotated Long Noncoding Ribonucleic Acids, Emily Coonrod
CTCF regulates the neuronal gene expression program, Alissa Cullen
Multi-omic analysis of phototrophic extracellular electron uptake in novel Rhodovulum spp. isolated from a marine estuary, Emily J. Davenport
Evaluating Pathological Tau Spread in Early Alzheimer Disease: Developing a Metric for Tau Positron Emission Tomography Quantifying Tau Spatial Spread, Stephanie Sierra Doering
Characterizing the Causal Role of SVEP1 in Human Disease, Jared S. Elenbaas
Dimerization of the Fluoride Channel Fluc in Membranes, Melanie Ernst
Tracking and Mitigating Imprint Erasure During Human Pluripotent State Transitions, Laura A. Fischer
Applications of Bioinformatics for Exploring the Genomic Landscape of Cancer and Characterizing Treatment Response for Precision Oncology, Sharon Freshour
The Cell Biology of Cryptococcal Capsule Production, Elizabeth Gaylord
Clock Hijackers: how Integration of Glioblastoma into Circadian Circuits Regulates Tumor Progression and Sensitivity to Current Therapies, Maria Felicita Gonzalez
Leveraging Microbes to Improve Cancer Outcomes, Olivia Nicole Gorushi
Developing Computational and Experimental Tools for Investigating Intrinsically Disordered Proteins and Biomolecular Condensates, Daniel Griffith
The clinical significance and genetic origin of p14ARF, Anna Louise Grobelny Guthrie
A Test of the Pioneer Factor Hypothesis for Silent Gene Activation, Jeffrey Hansen
Vascular Electrophysiology and Pathogenic Consequences of Cardiovascular KATP Channel Mutations, Alex Hanson