Theses/Dissertations from 2025
Leveraging Biomolecules to Illuminate the Landscape of RNA in Cells and Tissues, Alexandria Quillin
The role of the poly-N repeat in the Plasmodium falciparum histone acetyltransferase protein, PfGCN5, Kely Johana Rubiano Cardona
Characterization of Long-Noncoding RNAs in Prostate and Pancreatic Cancer Through Single Cell Transcriptomics, Debanjan Saha
Exploring the Thermal Physiology Evolution Across Mountain Slopes, Jhan Carlos Salazar Salazar
Robust Embeddings of Genetics, Anatomy, and State Decoded from a Neuron’s Activity, Aidan Schneider
Optimizing Massively Parallel Reporter Assays for In Vivo Neurogenomics: Tools to Decode Enhancer Function in the Brain, Din Selmanovic
Mechanisms of ssDNA Gap Resection in BRCA1-proficient and -deficient Cells, Isabelle Seppa
ACLY Is Required for NK Cell Effector Function by Regulating the Epigenome, Stacey Sohn
Depalmitoylation regulates metabolism and mitochondrial function, Sarah Lilly Speck
Needle in the Z-stack: Mapping the 3D Transition to Malignancy, Erik Storrs
Parental Guidance Suggested: Genetic, Epigenetic, and Environmental Factors Shape Allele-Specific Gene Regulation in Metabolic Traits, Celine Louise St. Pierre
Plant-Microbe Interactions Across Scales: Diversity, Disease, and Stress in Herbaceous Plant Communities, Philippa Tanford
Oxycodone Self-Administration Modulates Ventral Pallidal Neuron Activity and Plasticity, Jessica Tooley
The Role of IL-33 in Itch, Anna M. Trier
Cortical Functional Organization in Early Childhood, Jiaxin Tu
Computational Dissection of Innate Immune Cell States: Tissue-Driven Heterogeneity Across Human Development, Alina Ulezko Antonova
Direct and Indirect Factors Render LPS Essential to Gram-negative Bacterial Physiology, Ryan Adam Valdez
Mitochondria Transfer-based Therapy for the Mitochondrial Disease Leigh Syndrome, Stella Varnum
Investigating the effects of maternal separation on the locus coeruleus and negative affective behaviors in adulthood, Chayla Rene Vazquez
Investigating the interplay of genetic factors and viral infections in type 1 diabetes pathogenesis, Daniel Andre Veronese-Paniagua
Efficient packaging of HIV-1 genomes via recognition of its adenosine-rich content by a heterologous RNA-binding domain, Hung Ryan Vuong
Acquisition Algorithms for Protein Mass Spectrometry and Their Application to Clinical Proteomics, Nathan Wamsley
Advancing Precision Treatment of Multiple Myeloma with Single-Cell and Spatial Immune Profiling, Julia Wang
Dominant tree species as a driver of forest herb community assembly: The peculiar case of pawpaw (Asimina triloba), Anna Wassel
Proteogenomic Analysis to Inform Causal Gene Prioritization for Human Disease, Daniel Western
Leveraging arginine catabolism to treat metabolic complications, Yiming Zhang
Investigating the Genetics and Genomics of Vein of Galen Malformations, Shujuan Zhao
Theses/Dissertations from 2024
Cellular and Molecular Basis of CD4+ T Cell Help at the Effector Phase During Immunotherapy of MHC-II Negative Tumors, Samuel Oche Ameh
Aging Antiviral Immunity In The Central Nervous System: Mechanisms And Implications, Artem D. Arutyunov
Mechanisms of uropathogenic E. coli reservoir formation in the gastrointestinal tract, Philippe Nimma Azimzadeh
Mechanisms of uropathogenic E. coli reservoir formation in the gastrointestinal tract, Philippe Nimma Azimzadeh
Avian Adaptation to Thermal Gradients, Justin Wheeler Baldwin
Interleukin-1α and Leukemia Inhibitory Factor Promote Cancer-Induced Extramedullary Hematopoiesis, Derek Arthur George Barisas
Inducible CRISPR-Targeted ‘Knockdown’ of Human Gut Bacteroides in Mice Reveals Glycan Utilization Strategies, Zachary Beller
Development and Structure of Spinal Interneuron Connectivity in Larval Zebrafish, Saul Bello Rojas
A Filter-Based Model of Visual Recognition, Olivia Rose Bockler
Employing Single-Nucleus RNA-Seq to Uncover Genetic Factors of Alzheimer Disease, Logan Brase
Mechanism of Impaired CD8+ T Cell Activation During Ross River Virus Infection, Christopher Bullock
Predicting Cell Fate Using Single-Cell State and Lineage Information, Emily Grace Butka
Gnotobiotic Mouse Models For Characterizing the Role of the Microbiota On Undernutrition and Early Postnatal Brain Development, Alexandra Elizabeth Byrne
Developing tools to study the effect of the mechanical environment on plant cell growth and morphogenesis, Ryan Calcutt
Accumbal Plasticity and Associated Behavioral Adaptations in the Spared Nerve Injury Model of Chronic Neuropathic Pain, Yu-Hsuan Chang
Epigenetic Dynamics in Zebrafish Development and Regeneration, Yujie Chen
The Role of MiR-34a in Pathological Neovascularization as Seen in Age-Related Macular Degeneration, Jason Colasanti
Sustainable Plastics from Plastic metabolisms: Leveraging Purple Non-sulfur Bacteria for Polyhydroxyalkanoate Synthesis, Eric Michael Conners
Discovery and Functional Characterization of Proteins Encoded by Annotated Long Noncoding Ribonucleic Acids, Emily Coonrod
CTCF regulates the neuronal gene expression program, Alissa Cullen
Multi-omic analysis of phototrophic extracellular electron uptake in novel Rhodovulum spp. isolated from a marine estuary, Emily J. Davenport
Evaluating Pathological Tau Spread in Early Alzheimer Disease: Developing a Metric for Tau Positron Emission Tomography Quantifying Tau Spatial Spread, Stephanie Sierra Doering
Characterizing the Causal Role of SVEP1 in Human Disease, Jared S. Elenbaas
Dimerization of the Fluoride Channel Fluc in Membranes, Melanie Ernst
Tracking and Mitigating Imprint Erasure During Human Pluripotent State Transitions, Laura A. Fischer
Applications of Bioinformatics for Exploring the Genomic Landscape of Cancer and Characterizing Treatment Response for Precision Oncology, Sharon Freshour
The Cell Biology of Cryptococcal Capsule Production, Elizabeth Gaylord
Clock Hijackers: how Integration of Glioblastoma into Circadian Circuits Regulates Tumor Progression and Sensitivity to Current Therapies, Maria Felicita Gonzalez
Leveraging Microbes to Improve Cancer Outcomes, Olivia Nicole Gorushi
Developing Computational and Experimental Tools for Investigating Intrinsically Disordered Proteins and Biomolecular Condensates, Daniel Griffith
The clinical significance and genetic origin of p14ARF, Anna Louise Grobelny Guthrie
A Test of the Pioneer Factor Hypothesis for Silent Gene Activation, Jeffrey Hansen
Vascular Electrophysiology and Pathogenic Consequences of Cardiovascular KATP Channel Mutations, Alex Hanson
A Dynamic Duo: Investigating the Interactions between Xanthomonas citri pv. malvacearum and Pseudomonas syringae, Taylor Harris
Treatment Modifications and Development for Mucopolysaccharidosis Type I, Sarah Hurt
Treatment Modifications and Development for Mucopolysaccharidosis Type I, Sarah Hurt
Dissecting the role of chromatin remodeling in direct lineage reprogramming, Kunal Jindal
Gene Expression Regulation by AU-Rich Elements and AU-Rich Element Binding Proteins, Courtney Fay Jungers
The Role of Group 2 Innate Lymphoid Cells in Restoring Lung Health and Chitinase Function After Epithelial Injury, Haerin Jung
The Role of Group 2 Innate Lymphoid Cells in Restoring Lung Health and Chitinase Function After Epithelial Injury, Haerin Jung
Effects of Hypoxia on Monocyte Differentiation and Macrophage Specification during Ischemic Heart Injury, Farid Faridovich Kadyrov
Epigenetic Mechanisms and Senescence in Aging and Cancer, Alla Karpova
Molecular Mechanisms Behind Methionine-Derived Glucosinolate Diversity in Brassica Plants, Vivian Kitainda
PMP2+ SCs maintain the survival and functioning of large-caliber motor axons, Mikolaj Kozlowski
Stromal Reprogramming by FAK Inhibition Overcomes Radiation Resistance to Allow for Immune Priming and Response to Checkpoint Blockade, Varintra Lander
Deciphering Immune Suppression Mechanisms of Primary and Metastatic Breast Cancer, Seunghyun Lee
Mechanisms of Rod Photoreceptor Metabolism and Function in Health and Disease, Tae Jun Lee
Elucidating the role of astrocytes in norepinephrine neuromodulation, Katheryn Bry Lefton
N-methyl-D-aspartate (NMDA) Receptors Control Calcium Signaling in Striatal Neurons to Guide Value-based Learning, Alex Legaria Macal
Germline Genetic Determinates of Cancer and Pre-Malignant Conditions, Jie Liu
Understanding Sequence Determinants of Functional Protein Dynamics Using Biophysical Simulations and Experiments, Upasana Lakshmi Mallimadugula
Studying the Dynamics of Neuromodulators in the Brain by Fluorescence Lifetime Imaging, Pingchuan Ma
Island Hopping in the Tropics: Conservation Genetics, Speciation, and Biogeography in the Iconic Flowering Plant Group Hibiscus sect. Lilibiscus, Brock Mashburn
Cytoplasmic and Mitochondrial Calcium Influences Retinal Ganglion Cell Survival to Axon Injury, Sean McCracken
An Intronic Regulatory Element Limits Tcf7 Expression in Natural Killer Cells, Matthew Vincent McCullen
Germinal Center Persistence Diversifies B Cell Responses to Vaccination, Katherine Marie McIntire
Regulation of neuronal cell-type-specific transcription by non-CG methylation and MeCP2, James Russell Moore
Aging, Fast and Slow: Gene Expression Signatures of Physiological Age Vs. Future Lifespan in Caenorhabditis elegans, Matthew Mosley
Insights from open conformations of EcMscK, hTRPV4, and hHCN1 into the structural basis of ligand-regulated ion channel gating, Jonathan Mount
Understanding Gene Regulation by Non-CG DNA Methylation and MeCP2 at Cellular Resolution in the Brain, Mati Nemera
Determining the Role of DDR2 in Acquired Chemo-Resistance in Ovarian Cancer, Alyssa Oplt
Exploring the Homeostatic Functions and Driving Forces of Lymphatic Outflow Pathways from the Central Nervous System, Zachary Matthew Papadopoulos
Investigation of PHOTOPERIODIC CONTROL OF HYPOCOTYL 1’s Role in Promoting Phytochrome B-Photobody Phase Separation, Sarah Anne Pardi
The Challenges of Diet Generalism in a Microbial Predator, Dictyostelium discoideum, Shreenidhi Perukkaranai Madabhushi
Dual Modes of Dopamine Underly Distinct Facets of Impulsive Actions, Tzvia Pinkhasov