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Theses/Dissertations from 2025

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Cortical Functional Organization in Early Childhood, Jiaxin Tu

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Computational Dissection of Innate Immune Cell States: Tissue-Driven Heterogeneity Across Human Development, Alina Ulezko Antonova

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Direct and Indirect Factors Render LPS Essential to Gram-negative Bacterial Physiology, Ryan Adam Valdez

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Mitochondria Transfer-based Therapy for the Mitochondrial Disease Leigh Syndrome, Stella Varnum

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Investigating the effects of maternal separation on the locus coeruleus and negative affective behaviors in adulthood, Chayla Rene Vazquez

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Investigating the interplay of genetic factors and viral infections in type 1 diabetes pathogenesis, Daniel Andre Veronese-Paniagua

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Efficient packaging of HIV-1 genomes via recognition of its adenosine-rich content by a heterologous RNA-binding domain, Hung Ryan Vuong

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Acquisition Algorithms for Protein Mass Spectrometry and Their Application to Clinical Proteomics, Nathan Wamsley

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Advancing Precision Treatment of Multiple Myeloma with Single-Cell and Spatial Immune Profiling, Julia Wang

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Dominant tree species as a driver of forest herb community assembly: The peculiar case of pawpaw (Asimina triloba), Anna Wassel

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Proteogenomic Analysis to Inform Causal Gene Prioritization for Human Disease, Daniel Western

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Senescent Cancer-Associated Fibroblasts Mediate Immunosuppression and Promote Breast Cancer Progression, Jiayu Ye

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Leveraging arginine catabolism to treat metabolic complications, Yiming Zhang

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Investigating the Genetics and Genomics of Vein of Galen Malformations, Shujuan Zhao

Theses/Dissertations from 2024

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Exploring the role of tissue-resident T cells in neurotropic viral infections and opioid-induced immune disorders during exposure and withdrawal, Shenjian Ai

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Cellular and Molecular Basis of CD4+ T Cell Help at the Effector Phase During Immunotherapy of MHC-II Negative Tumors, Samuel Oche Ameh

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Aging Antiviral Immunity In The Central Nervous System: Mechanisms And Implications, Artem D. Arutyunov

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Mechanisms of uropathogenic E. coli reservoir formation in the gastrointestinal tract, Philippe Nimma Azimzadeh

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Mechanisms of uropathogenic E. coli reservoir formation in the gastrointestinal tract, Philippe Nimma Azimzadeh

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Avian Adaptation to Thermal Gradients, Justin Wheeler Baldwin

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Interleukin-1α and Leukemia Inhibitory Factor Promote Cancer-Induced Extramedullary Hematopoiesis, Derek Arthur George Barisas

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Inducible CRISPR-Targeted ‘Knockdown’ of Human Gut Bacteroides in Mice Reveals Glycan Utilization Strategies, Zachary Beller

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Development and Structure of Spinal Interneuron Connectivity in Larval Zebrafish, Saul Bello Rojas

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A Filter-Based Model of Visual Recognition, Olivia Rose Bockler

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Employing Single-Nucleus RNA-Seq to Uncover Genetic Factors of Alzheimer Disease, Logan Brase

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Mechanism of Impaired CD8+ T Cell Activation During Ross River Virus Infection, Christopher Bullock

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Predicting Cell Fate Using Single-Cell State and Lineage Information, Emily Grace Butka

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Gnotobiotic Mouse Models For Characterizing the Role of the Microbiota On Undernutrition and Early Postnatal Brain Development, Alexandra Elizabeth Byrne

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Developing tools to study the effect of the mechanical environment on plant cell growth and morphogenesis, Ryan Calcutt

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Accumbal Plasticity and Associated Behavioral Adaptations in the Spared Nerve Injury Model of Chronic Neuropathic Pain, Yu-Hsuan Chang

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Epigenetic Dynamics in Zebrafish Development and Regeneration, Yujie Chen

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Elucidating the first protective mutation from inherited Alzheimer’s Disease - Apolipoprotein E3 Christchurch (APOE3ch) and insights into APOE ligand-receptor interactions, Yun Chen

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The Role of MiR-34a in Pathological Neovascularization as Seen in Age-Related Macular Degeneration, Jason Colasanti

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Sustainable Plastics from Plastic metabolisms: Leveraging Purple Non-sulfur Bacteria for Polyhydroxyalkanoate Synthesis, Eric Michael Conners

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Discovery and Functional Characterization of Proteins Encoded by Annotated Long Noncoding Ribonucleic Acids, Emily Coonrod

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CTCF regulates the neuronal gene expression program, Alissa Cullen

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Multi-omic analysis of phototrophic extracellular electron uptake in novel Rhodovulum spp. isolated from a marine estuary, Emily J. Davenport

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Evaluating Pathological Tau Spread in Early Alzheimer Disease: Developing a Metric for Tau Positron Emission Tomography Quantifying Tau Spatial Spread, Stephanie Sierra Doering

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Characterizing the Causal Role of SVEP1 in Human Disease, Jared S. Elenbaas

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Dimerization of the Fluoride Channel Fluc in Membranes, Melanie Ernst

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Tracking and Mitigating Imprint Erasure During Human Pluripotent State Transitions, Laura A. Fischer

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Applications of Bioinformatics for Exploring the Genomic Landscape of Cancer and Characterizing Treatment Response for Precision Oncology, Sharon Freshour

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The Cell Biology of Cryptococcal Capsule Production, Elizabeth Gaylord

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Clock Hijackers: how Integration of Glioblastoma into Circadian Circuits Regulates Tumor Progression and Sensitivity to Current Therapies, Maria Felicita Gonzalez

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Leveraging Microbes to Improve Cancer Outcomes, Olivia Nicole Gorushi

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Developing Computational and Experimental Tools for Investigating Intrinsically Disordered Proteins and Biomolecular Condensates, Daniel Griffith

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The clinical significance and genetic origin of p14ARF, Anna Louise Grobelny Guthrie

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A Test of the Pioneer Factor Hypothesis for Silent Gene Activation, Jeffrey Hansen

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Vascular Electrophysiology and Pathogenic Consequences of Cardiovascular KATP Channel Mutations, Alex Hanson

A Dynamic Duo: Investigating the Interactions between Xanthomonas citri pv. malvacearum and Pseudomonas syringae, Taylor Harris

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Treatment Modifications and Development for Mucopolysaccharidosis Type I, Sarah Hurt

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Treatment Modifications and Development for Mucopolysaccharidosis Type I, Sarah Hurt

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Dissecting the role of chromatin remodeling in direct lineage reprogramming, Kunal Jindal

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Gene Expression Regulation by AU-Rich Elements and AU-Rich Element Binding Proteins, Courtney Fay Jungers

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The Role of Group 2 Innate Lymphoid Cells in Restoring Lung Health and Chitinase Function After Epithelial Injury, Haerin Jung

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The Role of Group 2 Innate Lymphoid Cells in Restoring Lung Health and Chitinase Function After Epithelial Injury, Haerin Jung

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Discovering and Characterizing Conserved Anthelmintic Targets in the Early Parasitic Stages of Gastrointestinal Nematodes, Hyeim Jung

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Effects of Hypoxia on Monocyte Differentiation and Macrophage Specification during Ischemic Heart Injury, Farid Faridovich Kadyrov

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Epigenetic Mechanisms and Senescence in Aging and Cancer, Alla Karpova

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Molecular Mechanisms Behind Methionine-Derived Glucosinolate Diversity in Brassica Plants, Vivian Kitainda

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PMP2+ SCs maintain the survival and functioning of large-caliber motor axons, Mikolaj Kozlowski

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Understanding mechanisms of local adaptation in white clover (Trifolium repens L.): insights from a phenotypic cline and population genomics, Wen-Hsi Kuo

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Stromal Reprogramming by FAK Inhibition Overcomes Radiation Resistance to Allow for Immune Priming and Response to Checkpoint Blockade, Varintra Lander

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Insulin-Independent Regulation of Type 1 Diabetes via Large Brown Adipocyte-Secreted Proteins and the Novel Glucagon Regulator, Nidogen2, Jeongmin Lee

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Deciphering Immune Suppression Mechanisms of Primary and Metastatic Breast Cancer, Seunghyun Lee

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Mechanisms of Rod Photoreceptor Metabolism and Function in Health and Disease, Tae Jun Lee

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Elucidating the role of astrocytes in norepinephrine neuromodulation, Katheryn Bry Lefton

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N-methyl-D-aspartate (NMDA) Receptors Control Calcium Signaling in Striatal Neurons to Guide Value-based Learning, Alex Legaria Macal

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Germline Genetic Determinates of Cancer and Pre-Malignant Conditions, Jie Liu

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Understanding Sequence Determinants of Functional Protein Dynamics Using Biophysical Simulations and Experiments, Upasana Lakshmi Mallimadugula

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Studying the Dynamics of Neuromodulators in the Brain by Fluorescence Lifetime Imaging, Pingchuan Ma

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Island Hopping in the Tropics: Conservation Genetics, Speciation, and Biogeography in the Iconic Flowering Plant Group Hibiscus sect. Lilibiscus, Brock Mashburn

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Cytoplasmic and Mitochondrial Calcium Influences Retinal Ganglion Cell Survival to Axon Injury, Sean McCracken

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An Intronic Regulatory Element Limits Tcf7 Expression in Natural Killer Cells, Matthew Vincent McCullen

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Germinal Center Persistence Diversifies B Cell Responses to Vaccination, Katherine Marie McIntire

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Regulation of neuronal cell-type-specific transcription by non-CG methylation and MeCP2, James Russell Moore

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Aging, Fast and Slow: Gene Expression Signatures of Physiological Age Vs. Future Lifespan in Caenorhabditis elegans, Matthew Mosley

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Insights from open conformations of EcMscK, hTRPV4, and hHCN1 into the structural basis of ligand-regulated ion channel gating, Jonathan Mount

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Understanding Gene Regulation by Non-CG DNA Methylation and MeCP2 at Cellular Resolution in the Brain, Mati Nemera

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Determining the Role of DDR2 in Acquired Chemo-Resistance in Ovarian Cancer, Alyssa Oplt

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Exploring the Homeostatic Functions and Driving Forces of Lymphatic Outflow Pathways from the Central Nervous System, Zachary Matthew Papadopoulos

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Investigation of PHOTOPERIODIC CONTROL OF HYPOCOTYL 1’s Role in Promoting Phytochrome B-Photobody Phase Separation, Sarah Anne Pardi

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The Challenges of Diet Generalism in a Microbial Predator, Dictyostelium discoideum, Shreenidhi Perukkaranai Madabhushi

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Dual Modes of Dopamine Underly Distinct Facets of Impulsive Actions, Tzvia Pinkhasov

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Understanding the Relationship between Genetic and Epigenetic Variation at a Species and Individual Level, Kara Quaid

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Inferring Function from Form: Subcortical Projection Cell Types in Rat Orbitofrontal Cortex, Suelynn Ren

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The Macrophage Autophagy-Lysosome System in Atherosclerosis Pathogenesis, Astrid Carolina Rodriguez Velez

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Novel Strategies to Target Uropathogenic Escherichia coli in the Bladder and Gut, Jesus Miguel Santiago Borges

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Novel Strategies to Target Uropathogenic Escherichia coli in the Bladder and Gut, Jesus Miguel Santiago Borges

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Investigating Tumor-Stroma Interactions During Ovarian Cancer Metastasis, Angela Marie Schab

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Aging Drives CD8 T Cells to Functional Extremes: From Non-Specific Cytotoxicity to Tissue-Mediated Exhaustion, Irina Shchukina

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Aging Drives CD8 T Cells to Functional Extremes: From Non-Specific Cytotoxicity to Tissue-Mediated Exhaustion, Irina Shchukina

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Insulin-like Growth Factor Regulation of Nutrition-Dependent Growth, Regeneration, and Tumorigenesis, Jonathan Lamouth Spalding

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Systemic Activation of the Axon Degeneration Executioner SARM1 Triggers Acute Hyperglycemia, Lillian Spatz

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Antimicrobial Mechanisms of Human Lipocalin-2, Lindsey Steinberg

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Investigating the Involvement of GABAergic Interneurons and a Gene Therapy Strategy for Epilepsy in CLN2 Disease, Keigo Takahashi

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The structural biology of gamma-4 CUP pili, Kevin Omeed Tamadonfar

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Elucidating the Heterogeneity and Epigenetic Determinants of Memory-like Natural Killer Cell Differentiation, Jennifer Tran

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Elucidating the Heterogeneity and Epigenetic Determinants of Memory-like Natural Killer Cell Differentiation, Jennifer Tran

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Rapid Unleashing Macrophage Efferocytic Capacity by Transcriptional Pause Release, Turan Tufan