Abstract
Bone metastasis in breast cancer patients is a prominent problem, with 70% of metastatic breast cancer patients having bone metastasis.[1] The resulting complications are painful and decrease patient survival rate.[1,3] This study is based on the previous lab work of Ross et al., who found that bone metastatic breast cancer cells over-express the integrin αvβ3. Through a series of in vitro experiments, this study sought to investigate the degree to which the single lipid membrane αvβ3-targeted nanoparticles could function as a less toxic and more effective treatment to bone metastatic breast cancer.
Document Type
Final Report
Class Name
Mechanical Engineering and Material Sciences Independent Study
Date of Submission
12-27-2022
Recommended Citation
Bridges, Mikayla, "Treating Triple Negative Breast Cancer with Targeted Nano-Therapy" (2022). Mechanical Engineering and Materials Science Independent Study. 204.
https://openscholarship.wustl.edu/mems500/204