Document Type

Technical Report

Publication Date

1990-10-01

Filename

WUCS-90-37.pdf

DOI:

10.7936/K78C9TMX

Technical Report Number

WUCS-90-37

Abstract

This report documents the intent and use of a suite of programs for simulating the production of DNA restriction fragment data, as might come from the biological laboratory doing work in DNA mapping. This suite includes programs for (a) creating a random strand of DNA, (b) creating random clones given a strand of DNA, (c) taking a clone and applying a restriction enzyme to create restriction fragments, and (d) creating a nucleotide map of how the clones relate to one another within the original DNA strand. Besides this fundamental software, there are a number of a programs for introducing different forms of random error (nre, nce) intro the restriction fragments produced, and aggregating and "filtering" the clones in different ways to select those with appropriate properties.

Comments

Permanent URL: http://dx.doi.org/10.7936/K78C9TMX

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