Document Type
Technical Report
Publication Date
2002-03-19
Technical Report Number
WUCSE-2002-2
Abstract
Due to increased production of human DNA sequence, it is now possible to explore and understand human genomic organization at the sequence level. In particular, we have studied one of the major organizational components of vertebrate genome organization previously described as isochores (Bernardi, 1993), which are compositionally homogeneous DNA segments based on G+C content. We have examined sequence data for the existence of compositionally differing regions and report that while compositionally homogeneous regions are present in the human genome, current isochore classification schemes are too brad for sequence-level data.
Recommended Citation
Rouchka, Eric C. and States, David J., "Compositional Analysis of Homogeneous Regions in Human Genomic DNA" Report Number: WUCSE-2002-2 (2002). All Computer Science and Engineering Research.
https://openscholarship.wustl.edu/cse_research/1137
Comments
Permanent URL: http://dx.doi.org/10.7936/K7GM85PV