Date of Award

Winter 12-15-2010

Author's School

Graduate School of Arts and Sciences

Author's Department


Degree Name

Doctor of Philosophy (PhD)

Degree Type



Method development combined with the significant advances of mass spectrometry (MS) promotes versatility of MS applications to biological research of both small molecules and macromolecules. In this thesis, three aspects of the application of MS-based approaches are discussed; they include (1) properties and their implications on toxicity of biologically important quinones, (2) sample preparation for nanoliter analysis, and (3) affinities of antibody-peptide interactions.


English (en)

Chair and Committee

Michael L. Gross

Committee Members

John-Stephen A. Taylor, Robert Blankenship, Liviu Mirica, Timothy Holy, Jeffrey P. Henderson


Permanent URL:

Available for download on Monday, December 15, 2110

Included in

Chemistry Commons