Cortical Components of Retrieval

Abstract

Broadly speaking, the goals of this thesis are to better understand the functional architecture underlying human left lateral parietal cortex (LLPC) and its contribution to memory retrieval. In order to do so, several techniques that utilize the blood oxygen level dependent (BOLD) functional MRI signal will be employed. These include: 1) meta-analyses of many functional activation (fMRI) studies to define a large LLPC region showing memory retrieval effects; 2) using the resting BOLD correlation between regions (rs-fcMRI) to define putative boundaries between separable areas within LLPC, 3) using modularity optimization in the context of rs-fcMRI to define sets of regions brain-wide and their relationships with putative LLPC brain areas, and 4) novel fMRI designs to characterize more completely functional differentiations between the parietal areas

Committee Chair

Steven E Petersen

Committee Members

Deanna M. Barch, Ian G. Dobbins, Kathleen B. McDermott, Marcus E. Raichle, Bradley L. Schlagger, Mark E. Wheeler

Comments

Permanent URL: https://doi.org/10.7936/K7H70CRQ

Degree

Doctor of Philosophy (PhD)

Author's Department

Biology & Biomedical Sciences (Neurosciences)

Author's School

Graduate School of Arts and Sciences

Document Type

Dissertation

Date of Award

Winter 12-15-2009

Language

English (en)

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