Document Type

Technical Report

Department

Computer Science and Engineering

Publication Date

2010

Filename

WUCSE-2010-11.pdf

DOI:

10.7936/K7J101DB

Technical Report Number

WUCSE-2010-11

Abstract

We present a framework for the construction of vascular systems based on optimality principles of theoretical physiology. Given the position and flow distribution of end points of a vascular system, we construct the topology and positions of internal nodes to complete the vascular system in a realistic manner. Optimization is driven by intravascular volume minimization with constraints derived from physiological principles. Direct optimization of a vascular system, including topological changes, is used instead of simulating vessel growth. A good initial topology is found by extracting key information from a previously optimized model with less detail. This technique is used iteratively in a multi-level approach to create a globally optimized vascular system. Most of this work was completed at Fraunhofer MeVis during the summer of 2004.

Comments

Permanent URL: http://dx.doi.org/10.7936/K7J101DB

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