This Spring 2018 Semester, I worked in the Musculoskeletal Soft Tissue Lab to help develop a protocol for testing the mechanical properties of a fiber in tendon called elastin. Most of this work was concentrated around replicating previous experiment’s protocols (2) for testing onto a new machine, designing new clamps for this machine to hold the tendon, and testing bovine tendon to see if the experimental protocol successfully replicated previous experiments. This work included using an Instron Machine, and creating a loading regimen that was the same for testing mouse tendon on a Biax Machine. I also began the process of changing the design of the clamps and machine in order to treat the tendons with an enzyme solution called elastase which is used to degrade the elastin in the tendon (3). Throughout the semester I was able to successfully replicate the protocol from previous experiments, as well as gather encouraging data on bovine tendon, which indicates the experiment will be replicable on the new machine. I’m also in the process of creating a final set of clamps which will later be machine and used for mechanical testing.
Mechanical Engineering and Material Sciences Independent Study
Date of Submission
Abraham, James and Lake, Spencer, "James Abraham Spring Independent Study Report" (2018). Mechanical Engineering and Materials Science Independent Study. 68.