White matter brain tissue is largely inaccessible and is therefore difficult to mechanically characterize although this would be useful in understanding injuries and injury prevention. Thus, soft gels and 3D bioprinted materials allow for the estimation of the mechanical properties of brain tissue through non-invasive means. Through previous studies, it is determined that brain tissue is inherently anisotropic. To properly model it, the use of anisotropic cubic, diamond, and vintile type lattice 10 x 10 x 10 cm cube structures were used in compression testing to determine the elastic modulus of each lattice type in each of its orientations. Each lattice was scaled by 2 times in its X-direction and remined the same in its Y and Z directions. It was found that anisotropy in the material produces greater overall stiffness in the lattice structure, although more testing is needed to verify the results of this original study.
Mechanical Engineering and Material Sciences Independent Study
Date of Submission
Mascot, Annabella, "Mechanical Characterization of 3D Printed Hydrogel Lattices" (2022). Mechanical Engineering and Materials Science Independent Study. 179.