Date of Award

Summer 8-15-2014

Author's School

School of Engineering & Applied Science

Author's Department

Electrical & Systems Engineering

Degree Name

Master of Science (MS)

Degree Type

Thesis

Abstract

In recent years, detection of biological interactions on single molecule level has aspired many researchers to investigate several optical, chemical, electrical and mechanical sensing tools. Among these tools, toroidal optical resonators lead the way in detection of the smallest particle/molecule with the real time measurements. In this work, bio-sensing capabilities of toroidal optical resonators are investigated. Bio-sensing is realized via measuring the analyte-antigen interaction while the antigen is immobilized through a novel functionalization method.

Not long ago, detection of single nanoparticles using optical resonators has been accomplished however the need for cost-effective and practical transducers demands simpler tools. A tapered optical fiber is a suitable and efficient candidate as a practical tool. In this work, single nanoparticle detection measurements are performed in aqueous solutions and detection limit of fiber taper is investigated.

Language

English (en)

Chair

Lan Yang

Committee Members

Srikanth Singamaneni

Comments

Permanent URL: https://doi.org/10.7936/K7RF5S0Z

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