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Theses/Dissertations from 2021

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Role of Secretory Leukocyte Protease Inhibitor in Urinary Tract Infection, Anne Rosen

Theses/Dissertations from 2020

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Genetic Interactions and Maternal Genes Modulate Congenital Heart Disease Risk, Ehiole Ogboma Akhirome

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Lymphatic Filariasis: Host and Parasite Factors and the Pathogenesis of Systemic Adverse Events Following Treatment, Britt Juul Andersen

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In Vivo Mechanisms of Natural Killer Cell Tolerance, Michael Bern

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Electrophysiology of the Inner Retina in Health and Disease: EAAT5 in the Rod Bipolar Cell and Oscillatory Potentials in Diabetes, Gregory William Bligard

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Transcription Factor-Mediated Epigenetic Regulation in the Healthy Brain and Neurological Disease, Alexander J. Cammack

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Mitochondrial Morphology, Oxidative Stress Resistance, and Pathogenesis in Cryptococcus neoformans, Andrew Lee Chang

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Nonsense Mediated RNA Decay Promotes Survival of Cells with Defective Splicing, Abigael Jeruto Cheruiyot

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Dendritic Cell Development and Function, Vivek Durai

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Structural Mechanism of Poxvirus Sabotage of T-cell Costimulation, Jabari Issa Elliott

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The Enzymatic Function of the TIR domain: From Axon Degeneration to Innate Immunity, Kow Essuman

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Post-Lysosomal Cholesterol Trafficking: Novel Tools and Insights, Mckenna Rae Feltes

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Multi-omics Integration for Gene Fusion Discovery and Somatic Mutation Haplotyping in Cancer, Steven Mason Foltz

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Cognitive Recovery in the Post-Infectious CNS, Charise Joy Garber

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FGF18 in Postnatal Lung Development, Andrew Hagan

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Joint Estimation of Perceptual, Cognitive, and Neural Processes, Katherine Heisey

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Developing Tools for Identifying Tissue-Specific Epigenetic Marks and Predicting DNA hydroxy/methylation, Yu He

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Effects of agonistic anti-CD137 antibody on chikungunya virus infection and B cell responses, Jun Hong

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Identification and Characterization of a Novel Non-homologous End Joining Factor MRI, Putzer Joseph Hung

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The Role of Apolipoprotein E in Alzheimer Disease: From Therapy to Mechanism, Tien-Phat Vuong Huynh

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Epigenetic Dynamics in Normal and Disease Models, Hyo Sik Jang

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Investigating the Role of Genetic Variants and Environmental Factors in the Trajectory of Substance Use Disorders, Linda Johnson

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Conformational Basis and Small Molecule Antagonists of E. coli Adhesion to the Urinary Tract, Vasilios Kalas

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Molecular Insights into Microbial Adhesion, Roger Davies Klein

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A Neuromodulatory Circuit Controls Glial Potassium Buffering to Regulate Neuronal Excitability in Drosophila melanogaster, Hailun Li

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Understanding the Molecular Pathogenesis of Retinal Neurodegeneration, Jonathan B. Lin

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Notch-Mediated Regulation of Atrial Arrhythmogenesis, Catherine Lipovsky

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Pathophysiology and Treatment of Murine Globoid Cell Leukodystrophy, Yedda Li

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Metabolic Requirements of NK Cell Responses to Viral Infection, Annelise Yoo Mah-Som

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Developmental Principles of Sensorimotor Coding in the Mammalian Cerebellum, Kelly Hill Markwalter

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Neuroimmunologic Regulation of Chronic Itch, Landon Kyle Oetjen

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Effects of Toxoplasma gondii Infection on NK Cells and ILC1s, Eugene Park

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Life of Tau: Oligomerization, CNS Extracellular Clearance and Role as Plasma Biomarker, Tirth Patel

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Elucidating the Effect of Myopathy-Causing Mutations and Second-Site Suppressors on Client Processing by J-Domain Proteins, Melanie Y. Pullen

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Signaling Mechanisms in Adaptive Immunity, Saravanan Raju

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Transcriptional and Epigenetic Regulation of Cerebellar Development and Function, Naveen C. Reddy

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Understanding emerging biomarkers and lifestyle factors in aging and Alzheimer disease, Stephanie Schultz

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Regulation and Function of TREM2-dependent Pathways in Neurodegeneration, Wilbur Madison Song

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Epigenetic and Signaling Pathways Regulating the Maintenance of CD8 T Cell Identity and Function, Daniel Verbaro

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Development of an in vitro Culture System for Cryptosporidium parvum, Georgia Wilke

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FGF20 in Olfactory System and Cochlea Development, Lu Morgan Yang

Theses/Dissertations from 2019

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Molecular Regulation of Vertebrate Pigmentation and Stem Cell Quiescence in Larval Zebrafish, James Randolph Allen

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A Combinatorial Approach of Ionomics, Quantitative Trait Locus Mapping, and Transcriptome Analysis to Characterize Element Homeostasis in Maize, Alexandra Asaro

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Development of Enteric Neurons and Muscularis Macrophages, Marina Avetisyan

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Understanding the Transcriptional Mechanisms Underlying Dendritic Cell Development, Prachi Bagadia

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The Role of Mitofusins in the Osteoclast Lineage, Anna Ballard

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The Role of Tumor Stromal Discoidin Domain Receptor 2 (DDR2) in Breast Cancer Metastasis., Samantha Van Hove Bayer

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Brain Blood Flow and Metabolism: Variable Relationships in Altered Metabolic States, Tyler M. Blazey

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A Noncanonical Function of the Telomerase RNA Component in Human Embryonic Stem Cells, Kirsten Ann Brenner

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Activation and Regulation of the ALKBH3-ASCC Alkylation Repair Pathway, Josh Brickner

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Defining Gastric Epithelial Cell Population Dynamics At Homeostasis And Following Injury, Joseph Ronald Burclaff

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Identifying Novel Regulators of Double Strand Break Repair and Replication Fork Protection, Andrea Karl Byrum

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Multi-omic Understanding of the Evolution of Xenobiotic Tolerance in Bacterial Isolates and Communities, Tayte Paul Campbell

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Beta-diversity, Environmental Change, and the Stability of Regional Ecosystems, Christopher P. Catano

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The Impact of Structural Variation on Human Gene Expression, Colby Chiang

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From Schwann Cells to Melanoma: Neural Crest Derived Cells in Development and Disease, Rebecca Lynng Cunningham

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The Role of Alternative NF-kB Signaling in Osteogenesis, Jennifer Davis

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Transcriptional Regulation of Adipose Tissue Development by PexRAP and Med19, John Dean

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Effects of Microbiota-Directed Fiber-Enriched Food Prototypes in Gnotobiotic Mice and Humans, Omar Delannoy-Bruno

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The Biomedical Application of Chimeric Antigen Receptor T cell Therapy, Jessica Devenport

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Dissemination of the apicomplexan parasite, Toxoplasma gondii, Lisa L. Drewry

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The Autophagy-Lysosome System in Cardiometabolic Disease, Trent Evans

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Characterizing the Humoral Response to Flavivirus Infection, Estefania Fernandez

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High-Density Diffuse Optical Tomography During Passive Movie Viewing: A Platform for Naturalistic Functional Brain Mapping, Andrew Kelsey Fishell

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High-Density Diffuse Optical Tomography During Passive Movie Viewing: A Platform for Naturalistic Functional Brain Mapping, Andrew Kelsey Fishell

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Genomic Signatures of Conflict and Cooperation in Plants and Social Amoebae, Katherine Sylvia Geist

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Discoidin Domain Receptor 2 as a Therapeutic Target in Breast and Ovarian Cancer, Whitney Grither

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Understanding the Physiology of Extracellular Electron Uptake in Purple Nonsulfur Bacteria, Michael Singh Guzman

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Regulation of the Yeast Cell Cycle Checkpoint Kinase Tel1 at Double-Strand DNA Breaks and at Telomeres, Sarem Hailemariam

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T cell Immunity in Pancreatic Cancer is Undermined by Dendritic Cell Dysfunction, Samarth Hegde

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The Role of Rifampicin Resistance Mutations in Host Immune Modulation by Mycobacterium tuberculosis, Nicole Christine Howard

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Mapping and Functional Analysis of cis-Regulatory Elements in Mouse Photoreceptors, Andrew Hughes

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The Transcription Factor Bhlhe40 Regulates Tissue-Resident Macrophages and Type 2 Immunity, Nicholas N. Jarjour

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Coordinated Control of Carbon Metabolism in Plasmodium falciparum, Andrew James Jezewski

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From Single Cells to Human Disease: High-resolution Phenotyping of Male Infertility Models Using Single-cell RNA Sequencing, Min Jung

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Investigation of immunostimulatory commensal bacteria in health and immune mediated disorders, Sunaina Khandelwal

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Aging of the Reproductive System and of Germline Stem Cells in Caenorhabditis, Zuzana Kocsisova

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Determining the Genetic Contributions of the Williams Syndrome Critical Region to Behavior Using Mouse Models and Human Genetics, Nathan David Kopp

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Determining the Genetic Contributions of the Williams Syndrome Critical Region to Behavior Using Mouse Models and Human Genetics, Nathan David Kopp

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Molecular Mechanisms Responsible for Functional Cortical Plasticity During Development and after Focal Ischemic Brain Injury, Andrew Wiggen Kraft

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Mesothelium-derived factors shape tissue resident macrophage, Chin-Wen Lai

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The Degenerating Star Clock: Circadian Clock Regulation of Astrogliosis and Implications for Alzheimer’s Disease, Brian Vincent Lananna

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A Molecular Logic of Sensory Coding Revealed by Optical Tagging of Physiologically-Defined Neuronal Types, Donghoon Lee

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A Molecular Logic of Sensory Coding Revealed by Optical Tagging of Physiologically-Defined Neuronal Types, Donghoon Lee

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Finding and Analyzing de novo Mutations in the Exomes of Parent-Offspring Trios of Spontaneous Chiari Malformation Type 1 Patients, Brian Leon Ricardo

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The Role of IFRD1 in the Recruitment and Function of Reserve Stem Cells in Regeneration and Cancer, Mark Anthony Lewis

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Glycan Precursor Transport in Cryptococcus neoformans, Lucy X. Li

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Integrative Analysis to Investigate Complex Interaction in Alzheimer’s Disease, Zeran Li

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Development of Novel Tumor-Targeted Compounds for Boron Neutron Capture Therapy, Micah John Luderer

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The Role of Natural Killer Cells in Atopic Dermatitis, Madison R. Mack

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Transcriptional and Epigenetic Regulation of Axon Regeneration, Marcus Mahar

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Elucidating Enhancer Function in Epidermal Development and Filaggrin Loss-of-Function Variants in African American Atopic Dermatitis, Mary Elizabeth Mathyer

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Deciphering the Origins of Cell-Type Differentiation Using the Simple Multicellular Green Alga Volvox carteri, Gavriel Yonah Matt

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Visual and Chemosensory Pathways Associated With Male Courtship Decisions in Drosophila melanogaster, Ross Mckinney

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Visual and Chemosensory Pathways Associated With Male Courtship Decisions in Drosophila melanogaster, Ross Mckinney

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Substrate reduction therapy for Krabbe disease and a new murine model for cell-autonomous expression of lysosomal hydrolases, Christina Ruth Mikulka

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Spatio-temporal Principles of Infra-slow Brain Activity, Anish Mitra

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Computational Approaches for Multispecies and Metaproteomic Analyses, Arshag Mooradian

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Typical and atypical development of the brain’s functional network architecture, Ashley Nicole Nielsen

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Mechanism of Activation of UvrD Helicase by a Processivity Factor MutL, Yerdos Ordabayev