Abstract

Enzymes are naturally occuring sustainable catalysts that offer competitive catalysis to synthetic routes. There exist growing demands for environmentally-friendly and sustainable catalysis, which have led to a surge of research in biocatalysis. 1-3 However, the major bottleneck for the industrial applications of enzymes is the long term operational stability and difficultly in recovery and reusability of enzymes. 4-6 The goal of this study was to develop biocatalytic surface with organo-silica enzyme imprints that can recover, stabilize and reuse enzymes. The complete encapsulation was expected to enhance thermal and chemical stability, and the plasmonic nanostructures were expected to provide the ability to enhance the biocatalytic activity when light was used as an external trigger. The target enzyme was horseradish peroxidase (HRP).

Document Type

Final Report

Author's School

School of Engineering and Applied Science

Author's Department

Mechanical Engineering and Materials Science

Class Name

Mechanical Engineering and Material Sciences Independent Study

Date of Submission

12-20-2016

Available for download on Wednesday, December 20, 2017

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