Theses/Dissertations from 2017
Knowledge Driven Approaches and Machine Learning Improve the Identification of Clinically Relevant Somatic Mutations in Cancer Genomics, Benjamin John Ainscough
Mechanism of Gene Regulation by Coding PolyA Tracks, Laura Lea Arthur
Mitochondrial damage accumulation in oocytes – a potential link between maternal obesity and increased cardiometabolic disease risk in offspring., Anna Louise Boudoures
The Role of RNA Interference in the Control of Leishmania RNA virus 1 Infection, Erin Acino Brettmann
Mitochondrial Dynamics Controls T Cell Fate Through Metabolic Programming, Michael Buck
Quantitative profiling of cooperative transcription factors pairing on hundreds of sequences in parallel, Yiming Chang
Regulation of Early Zebrafish Embryogenesis by Calcium Signaling and Dachsous1b Cadherin, Jiakun Chen
Exploring Host-Virus Interactions in Caenorhabditis Nematodes, Kevin Chen
Regulation of gene expression by RNA binding proteins and microRNAs, Kyle Cottrell
Characterization of ZIP genes responsible for zinc homeostasis in C. elegans, Nicholas Dietrich
Hepatic Ketogenesis as a Novel Regulator of Liver Metabolism and Injury, Baris Can Ercal
Characterization and Function of Islet Antigen Presenting Cells during NOD Diabetes, Stephen Thomas Ferris
Regulation of the Pro-Tumorigenic Senescence-Associated Secretory Phenotype, Kevin Flanagan
Roles of Peroxisomes and Peroxisome-Derived Products in Controlling Plant Growth and Stress Responses, Elizabeth May Frick
Recent Positive Selection of the Epidermal Differentiation Complex in Mammals, Primates, and Humans, Zane Alexander Goodwin
Flaviviruses: Innate Immune Restriction and Host Adaptation, Matthew Joseph Gorman
Genetic and genomic dissections of myelinating glial cell development, Breanne Leigh Harty
The RpL13a snoRNA U33 Forms Novel snoRNPs During Lipotoxicity, Miquia Sherree Henderson
The Regulation of Extracellular Amyloid-β Levels by Ionotropic Glutamatergic Transmission in an Alzheimer’s Disease Mouse Model, Jane Cecelia Hettinger
Sequence Determinants of the Individual and Collective Behaviour of Intrinsically Disordered Proteins, Alexander S. Holehouse
Analysis of Argonaute-Small RNA-Transcription Factor Circuits Controlling Leaf Development, John Steen Hoyer
Epigenetic Regulation of Lymphocyte Development and Transformation, Yue Huang
Specificity Determination by paralogous winged helix-turn-helix transcription factors, Adam Joyce
Mechanisms of G Protein Regulation by RGS Proteins and Small Molecule Inhibitors, Stanley Michinobu Kanai
Factors that Contribute to de novo Protein Misfolding and Prion Formation in Saccharomyces cerevisiae, Kathryn Morgan Keefer
The Effect of Dietary Fat on Obesity, Gene Expression, and DNA Methylation in Two Generations of Mice, Madeline Rose Keleher
Motion processing in the mouse retina, Tahnbee Kim
Structural, Biophysical, and Functional Studies of TREM2 In Neurodegenerative Disease, Daniel L. Kober
Targeting the Response to Arginine Starvation in ASS1-Deficient Sarcomas, Jeff Kremer
Expansion of Microbial Virology by Impetus of the Reduction of Viral Dark Matter, Siddharth Ravindran Krishnamurthy
Glucose Metabolism in Plasma Cell Populations in the Bone Marrow and Spleen, Wing Yu Lam
Functional Brain Organization in Space and Time, Timothy Laumann
Epigenome Dynamics in Vertebrate Development and Regeneration, Hyung Joo Lee
Nuclear export factor 3 regulates the localization of small nucleolar RNAs, Melissa Wanling Li
The Role of Bhlhe40 in Autoimmune Neuroinflammation and Mycobacterial Infection, Chih-Chung Lin
Metabolic Modulation of Bacterial Resistance to Alpha-Defensins, Christine Tzy-Yuh Luo
Discovery and Characterization of Rv0004 as a Novel and Essential Part of the Mycobacterial DNA Replication Machinery, Katherine Mann
The Role of VIP SCN Neurons in Circadian Physiology and Behavior, Cristina Mazuski
Designing Epigenome Editing Tools to Understand the Functional Role of DNA Methylation Changes in Cancer, James Mcdonald
Beta-Diversity Patterns and Community Assembly across Latitudes, Emma Moran
The Development and Characterization of New Models of Recurrent Urinary Tract Infection, Valerie Phoebe O'brien
Novel Insights into Yersiniabactin Biosynthesis in Uropathogenic Escherichia coli, Shannon Ileen Ohlemacher
The Role of Histidine Rich Protein II in Cerebral Malaria, Priya Pal
DNA Replication Challenges: Telomeres and R loops, Shankar Parajuli
Mechanisms and Regulation of Resection in DNA Damage Response, Sharad C. Paudyal
Identification and Characterization of an Interferon Stimulated Gene That Restricts Alphavirus Infection and Pathogenesis, Subhajit Poddar
Metabolic regulation of CD8 T cell functions in the tumor microenvironment, Jing Qiu
Antiviral Nucleoside Inhibitors of Leishmania RNA Virus 1: Discovery and Mechanism, John Isaac Robinson
Identification of Novel Variants Associated with Alzheimer’s Disease Using Quantitative Traits, Yuetiva Karenina Robles
A Generalized Biophysical Model of Transcription Factor Binding Specificity and Its Application on High-Throughput SELEX Data, Shuxiang Ruan
Determining the Molecular Mechanisms of Huntington’s Disease through Multi-Scale Modeling, Kiersten Ruff
Biophysical studies of the intracellular domains of the EGFR family of Receptor Tyrosine Kinases, Kwabena A N Sarpong
Modeling Complex Patterns of Differential DNA Methylation That Associate with Expression Change, Christopher E. Schlosberg
Understanding the paradox of genetic diversity in uropathogenic E. coli: the uncommon evolution of a common pathogen, Henry Louis Schreiber
The Effects of the Gut Microbiota on the Host Chromatin Landscape, Nicholas Semenkovich
Bridging the translational gap between rodent and human pain research, Tayler Diane Sheahan
Investigation of the Contribution of Type 1 Pili in Enterotoxigenic Escherichia Coli (ETEC) Pathogen-Host Interactions, Alaullah Sheikh
Investigating the Role of GH3 Acyl Acid Amido Synthetases in Plant Hormone Homeostasis, Ashley Marie Sherp
Robust Algorithms for Detecting Hidden Structure in Biological Data, Roman Sloutsky
Type 1 and F17-like Pili Promote the Establishment of the Uropathogenic E. coli Intestinal Reservoir, Caitlin Nicole Spaulding
Longitudinal Cerebrospinal Fluid Biomarkers of Alzheimer Disease: Movement Toward the Diagnosis, Prognosis and Staging of Disease, Courtney Sutphen
Modeling Huntington's Disease With Neurons Directly Converted from Patient Fibroblasts, Matheus B. Victor
Influenza A virus Genomic Reassortment and Packaging, Graham Devin Williams
Epigenetic Activation of the Mouse T Cell Receptor Beta Recombination Center, Jiangyang Zhao
Defining the Ontogeny and Functions of Macrophages in Pancreatic Ductal Adenocarcinoma, Yu Zhu
Theses/Dissertations from 2016
Mechanisms of Myelination, It's All About the Matrix, Sarah Degenova Ackerman
Circuit Mechanisms of Spontaneous and Light Evoked Activity in the Retina, Alejandro Akrouh
Health Implications of Excess Fructose Consumption and Increased Risk for Offspring Diseases, Zeenat Afshan Asghar
Engineering Escherichia coli towards the production of branched-chain advanced biofuels, Gayle Joann Bentley
Action of SNAIL1 Protein is Critical for Fibrosis, Hirak Biswas
Disrupted Gut Microbiota Development and Childhood Undernutrition, Laura Vanarendonk Blanton
The Molecular and Cellular Basis for Cold Sensation, Daniel Brenner
Regulation of durable adaptive immune response by the c-MYC-AP4 transcriptional cascade, Chun Chou
The Role of DNMT3A in Acute Myeloid Leukemia Pathogenesis, Christopher Browning Cole
Characterization of Salivary Gland Innate Lymphoid Cells, Victor Samuel Cortez
Superoxide Dismutase 1: Novel Insights on Disease Models and Tissue Specificity in Amyotrophic Lateral Sclerosis, Matthew James Crisp
Granulocyte-Colony Stimulating Factor Reprograms the Bone Marrow Microenvironment to Suppress B Lymphopoiesis, Ryan Brent Day
Population Structure and Mating Dynamics in the Social Amoeba Dictyostelium discoideum, Tracy Edwards Douglas
New Regulators of Auxin Response Reveal Insights into Cell Expansion, Tara Ann Enders
Mitochondrial Transport and Function in Development and Disease, Michelle Faits
The Resolution Phase of NK Cell Proliferation and IFN Production Following Viral Infection Are Highly Regulated Processes., Leslie Abigail Fogel
Regulation of Transcription and Stress Response by CarD in Mycobacteria, Ashley Louise Garner
Molecular Studies of SARM1, an Axonal Self-Destruction Switch, Josiah Gerdts
Regulation and Inhibition of Uropathogenic E. coli Extracellular Appendages, Sarah Elizabeth Greene
Ecological and Genetic Consequences of Climate Change Impacting Species Distributions, with Specific Cases in Whitebark Pine (Pinus albicaulis Engelm.), Jennifer A. Gruhn
Discovery and characterization of a novel class of metabolic regulators in the malaria parasite Plasmodium falciparum, Ann Marie Guggisberg
The Murine Accessory Olfactory Bulb as a Model Chemosensory System: Experimental and Computational Analysis of Chemosensory Representations, Gary Francis Hammen
Molecular Mechanisms Mediating the Effects of Acute Dietary Vitamin A Deficiency on a Defined Model Human Gut Microbiota, Matthew Charles Hibberd
The Maintenance of Age in Reprogrammed Human Neurons, Christine Jean Huh
Targeting Isoprenoid Biosynthesis in Plasmodium falciparum, Leah Imlay
Mechanisms of Extracellular Vesicle Biogenesis, Charles Eldon Jackson
Characterization of autophagy-dependent and independent roles of ATG5 in controlling Mycobacterium tuberculosis infection, Jacqueline M. Kimmey
Structure-Function Analysis of Blue Copper Proteins, Jeremy D. King
Metal Selectivity and Acquisition by the Yersiniabactin Metallophore System in Escherichia coli, Eun-Ik Koh
Modulation of Human and Malarial Glucose Transporter Activity by Lipids and Small Molecules, Thomas E. Kraft
Epigenomics of Cell Fate in Development and Disease, Rebecca Faith Lowdon