Theses/Dissertations from 2021
Deep Learning Deleterious Small Molecule Biochemistry from the Lab to the Clinic, Matthew Matlock
Investigation of IFNγ-induced Control of Intracellular Pathogens, Michael Mcallaster
Ascension and Adhesion of Uropathogenic Escherichia coli during Pyelonephritis, Lisa Kristine McLellan
Modularity of Feedback for State-Dependent Guidance of Navigation in Mouse Visual Cortex, Andrew M. Meier
Developments in Proteomics, Trans-Splicing Technology And Endogenous Transcript Manipulation, Justin Alexander Melendez
The Role of Subclonal Gene Mutations During Progression from Myelodysplastic Syndrome to Secondary Acute Myeloid Leukemia, Andrew John Menssen
A Novel Function of Plasmacytoid Dendritic Cells in Regulating Type 2 Immune Responses, Hannah Leigh Miller
Prodrug Activation in Staphylococci and the Implications for Antimicrobial Development, Justin J. Miller
Exploring β-cell Function and Heterogeneity in Obese SM/J Mice, Mario Alejandro Miranda
Deconvolving Genomic Regulatory Heterogeneity with Self-Reporting Transposons, Arnav Moudgil
The roles of plasmepsins IX and X in malaria parasite biology, Armiyaw Sebastian Nasamu
The evolving mammalian 3D epigenome, Mayank Choudhary Nishikant Choudhary
Metabolic Control and Immune Barriers of Hematopoietic Stem Cells, Hannah Pizzato
Regulation of Host-Microbe Interactions in Autoimmunity and Antiviral Immunity by Cytosolic Nucleic Acid Sensing and Interferon Signaling, Derek Jerome Platt
On the challenges and rewards of analyzing molecular dynamics at the terabyte and millisecond scale, Justin Roy Porter
RNA Polymerase Binding Protein A (RbpA) Regulation of Mycobacteria Transcription and Sensitivity to Fidaxomicin, Jerome Prusa
Genetic Variations in the Regulation and Biosynthesis of Polycyclic Tetramate Macrolactams, Yunci Qi
The Role of Mature Secretory Cells in Gastrointestinal Regeneration, Megan Deanna Radyk
Functional Optical Imaging of the Developing Mouse Cortex in Health and Disease, Rachel Marlene Rahn
Comprehensive Characterization of the Genetic and Neoantigen Landscapes of Follicular Lymphoma Patients Supports the Feasibility of Personalized Cancer Vaccine Treatments, Cody Alexander Ramirez
Targeting the PHGDH-mTOR Metabolic Axis in Osteosarcoma, Richa Rathore
Exploring the intrinsic and extrinsic factors that regulate breast cancer cell dormancy, Qihao Ren
The Origins & Functional Effects of Postzygotic Mutations Throughout the Human Lifespan, Nicole Briana Rockweiler
Discovery of Sex Differences in Response to p53 Loss and Gain-of-Function in Glioblastoma, Nathan Cuyle Rockwell
Role of Secretory Leukocyte Protease Inhibitor in Urinary Tract Infection, Anne Rosen
Influence of Focal Activity on Macroscale Brain Dynamics in Health and Disease, Zachary Pollack Rosenthal
Investigating the Role of Bladder Epithelial Stem Cells in Bladder Mucosal Remodeling and Defense Against Infection, Seongmi Kim Russell
Regulation of Gut Commensal-Specific T Cell Differentiation by Dendritic Cell Subsets, Emilie Russler-Germain
Measuring and Manipulating Tension-Dependent Behavior of Mechanosensitive Ion Channels, Angela M. Schlegel
Structural Variants Are a Major Source of Gene Expression Differences in Humans and Often Affect Multiple Nearby Genes, Alexandra Jane Scott
Precision Diffusion Imaging to Analyze Individual-Specific Plasticity, Nicole Andrea Seider
Relating Spontaneous Activity and Cognitive States via NeuroDynamic Modeling, Matthew Singh
Understanding and Exploiting Protein Allostery and Dynamics Using Molecular Simulations, Sukrit Singh
Regulation of Metabolic Stress by the Snhg3 Locus, Arthur Curtis Sletten
Characterizing a Novel Metabolic Pathogenic Mechanism in Familial Hemiplegic Migraine, Sarah Elizabeth Smith
Glial inflammatory responses regulate neurocognitive recovery following viral encephalitis, Allison Luen Soung
Role of Interferon Receptors in STING-Associated Autoinflammatory Disease in Mice, William Alexander Stinson
Structural Analysis and Vaccine Efficacy of Hla mutants, Kelly Tomaszewski
Uncovering a MYC-driven Tumor-suppressive Program in Proliferating Lymphocytes, Elena Tonc
Investigating the differentiation and functional maturation of stem cell-derived β cells, Leonardo Velazco-Cruz
Mechanisms of Natural Killer Cell Anti-Tumor Function and Homeostasis, Julia Alexandra Wagner
Peripheral Nerve Macrophages and Their Implications in Neuroimmunity, Peter Leon Wang
Regional Reprogramming and the Small Intestine: Analysis and Modeling of Adaptive Regeneration of the Epithelium, Sarah Elizabeth Waye
Weedy rice as a model system for the study of microevolutionary interactions in agricultural contexts, Marshall Jon Wedger
Genetic risk factors for neurodevelopmental disorders: insights from hiPSC-cerebral organoids, Michelle L. Wegscheid
Of Mice and Toddlers: A Cross-Species Investigation of the Social Motivation Theory of Autism, Claire Weichselbaum
Causal Function and Bias Correlation of the Orbitofrontal Cortex in Economic Choices, Shi Weikang
Computational Analysis of Non-CpG DNA Methylation in the Mammalian Nervous System, Dennis Yawen Wu
Apolipoprotein E Immunotherapy for the Preclinical Treatment of Alzheimer Disease and Cerebral Amyloid Angiopathy, Monica Xiong
The Role of Neuronal ATP-sensitive Potassium Channels in Learning and Memory, Shaul Vladimir Yahil
Contribution of TGF-b Signaling to the Pathogenesis of Myeloproliferative Neoplasms, Juo-Chin Yao
Disentangling Glial Diversity in Peripheral Nerves at Single Nuclei Resolution, Aldrin Kay Yuen Yim
The Role of eNAMPT-mediated Systemic NAD+ Biosynthesis in Aging and Lifespan, Mitsukuni Yoshida
Theses/Dissertations from 2020
Genetic Interactions and Maternal Genes Modulate Congenital Heart Disease Risk, Ehiole Ogboma Akhirome
Lymphatic Filariasis: Host and Parasite Factors and the Pathogenesis of Systemic Adverse Events Following Treatment, Britt Juul Andersen
Structural insights into host-pathogen interactions of alphaviruses, Katherine Basore
Mechanisms of STING-Associated Vasculopathy and Immunodeficiency, Brock Gordon Bennion
In Vivo Mechanisms of Natural Killer Cell Tolerance, Michael Bern
Electrophysiology of the Inner Retina in Health and Disease: EAAT5 in the Rod Bipolar Cell and Oscillatory Potentials in Diabetes, Gregory William Bligard
Transcription Factor-Mediated Epigenetic Regulation in the Healthy Brain and Neurological Disease, Alexander J. Cammack
The Good, The Brown, and The Healthy: Understanding Non-Thermogenic Brown Adipose Function in Obese Mice, Caryn Nicole Carson
Regulation of Yolk Microtubule Dynamics by Dachsous Cadherins, Gina Danielle Castelvecchi
Mitochondrial Morphology, Oxidative Stress Resistance, and Pathogenesis in Cryptococcus neoformans, Andrew Lee Chang
Characterizing the relationship between gut microbiota development and healthy growth, Hao-Wei Chang
Nonsense Mediated RNA Decay Promotes Survival of Cells with Defective Splicing, Abigael Jeruto Cheruiyot
The Role of ESCRT-III-like Subunit IST1 in Membrane Trafficking Pathways, Amy Kate Clippinger
The role of CDX4 during patterning of definitive hemogenic mesoderm, John Philip Creamer
Dendritic Cell Development and Function, Vivek Durai
Structural Mechanism of Poxvirus Sabotage of T-cell Costimulation, Jabari Issa Elliott
Advances in the Understanding of Auxin Signaling Through Indirect Mechanisms, Ryan Joseph Emenecker
The Enzymatic Function of the TIR domain: From Axon Degeneration to Innate Immunity, Kow Essuman
The Decision Maker: Understanding the role of IFRD1 in urothelial plasticity and regeneration, Bisiayo Erionmwon Fashemi
Post-Lysosomal Cholesterol Trafficking: Novel Tools and Insights, Mckenna Rae Feltes
Multi-omics Integration for Gene Fusion Discovery and Somatic Mutation Haplotyping in Cancer, Steven Mason Foltz
Cognitive Recovery in the Post-Infectious CNS, Charise Joy Garber
The Role of the Circadian Clock Protein Rev-erba in Neuroinflammation & Synaptic Health, Percy Griffin
FGF18 in Postnatal Lung Development, Andrew Hagan
A mechanistic and genomic analysis of molluscum contagiosum virus immune evasion, Ian Benjamin Harvey
Joint Estimation of Perceptual, Cognitive, and Neural Processes, Katherine Heisey
Effects of agonistic anti-CD137 antibody on chikungunya virus infection and B cell responses, Jun Hong
Identification and Characterization of a Novel Non-homologous End Joining Factor MRI, Putzer Joseph Hung
The Role of Apolipoprotein E in Alzheimer Disease: From Therapy to Mechanism, Tien-Phat Vuong Huynh
Pathophysiology and proteogenomics of post-infectious and post-hemorrhagic hydrocephalus in infants, Albert M. Isaacs
Epigenetic Dynamics in Normal and Disease Models, Hyo Sik Jang
Investigating the Role of Genetic Variants and Environmental Factors in the Trajectory of Substance Use Disorders, Linda Johnson
Conformational Basis and Small Molecule Antagonists of E. coli Adhesion to the Urinary Tract, Vasilios Kalas
Structural and Functional Insights into Alphavirus-Host Interactions, Arthur S. Kim
Molecular Insights into Microbial Adhesion, Roger Davies Klein
Understanding the Molecular Pathogenesis of Retinal Neurodegeneration, Jonathan B. Lin
Notch-Mediated Regulation of Atrial Arrhythmogenesis, Catherine Lipovsky
Pathophysiology and Treatment of Murine Globoid Cell Leukodystrophy, Yedda Li
Delineating the Role of MiR-124 for the Activation of Neuronal Program, Ya-Lin Lu
Metabolic Requirements of NK Cell Responses to Viral Infection, Annelise Yoo Mah-Som
Developmental Principles of Sensorimotor Coding in the Mammalian Cerebellum, Kelly Hill Markwalter
Modeling HER2 Mutations in Colorectal Cancer using a HER2 Transgenic Mouse Model and Gastrointestinal Organoids, Elisa Murray