Author's School

Arts & Sciences

Author's Department

Biology

Document Type

Article

Publication Date

10-23-2015

Originally Published In

Science. 2015 Oct; 50(6259):438-441. doi: 10.1126/science.aac6014.

Abstract

Pollen grains undergo dramatic changes in cellular water potential as they deliver the male germ line to female gametes, and it has been proposed that mechanosensitive ion channels may sense the resulting mechanical stress. Here, we identify and characterize MscS-like 8 (MSL8), a pollen-specific, membrane tension–gated ion channel required for pollen to survive the hypoosmotic shock of rehydration and for full male fertility. MSL8 negatively regulates pollen germination but is required for cellular integrity during germination and tube growth. MSL8 thus senses and responds to changes in membrane tension associated with pollen hydration and germination. These data further suggest that homologs of bacterial MscS have been repurposed in eukaryotes to function as mechanosensors in multiple developmental and environmental contexts.

Comments

Final author manuscript version of article published in Science. 2015 Oct; 50(6259):438-441. doi: 10.1126/science.aac6014.

DOI

10.1126/science.aac6014

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